Observations on twinning in marmosets

Wislocki, George B.

doi:10.1002/aja.1000640305

Cited by 122 publications

(63 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is unclear whether this is the case in New World monkeys. In marmosets, which produce variations of bidiscoid placentae (Wislocki, 1939), a uniform membrane transformation occurring throughout the uterine lumen has been described in luminal epithelia during the preimplantation period of conceptual cycles, but phase-matched late luteal nonconceptual cycles were not included in the study (Niklaus et al, 2001). The only New World monkey (Cebus apella) in which uterine Muc-1 expression has been examined produces a bidiscoid placenta.…”

Section: Discussionmentioning

confidence: 99%

Compartmental distinctions in uterine Muc-1 expression during early pregnancy in cynomolgous macaque (Macaca fascicularis) and baboon (Papio anubis)

Julian¹,

Enders²,

Fazleabas³

et al. 2005

Human Reproduction

View full text Add to dashboard Cite

BACKGROUND: Loss of the transmembrane mucin, Muc-1, is a molecular correlate of the acquisition of uterine receptivity to embryo adhesion in most species examined. In macaques, two distinct adhesion events occur at opposite sides of the uterus. Attachment to the secondary site is delayed relative to the primary site. The aim was to determine if Muc-1 is removed at secondary sites prior to trophoblast attachment. METHODS: We examined Muc-1 expression in the uteri of cynomolgus macaque and baboon during early implantation by immunocytochemistry. RESULTS: Luminal epithelia were devoid of Muc-1 at all stages examined at both primary and secondary adhesion sites. Loss of Muc-1 in luminal epithelia was found to be maternally determined, accompanied membrane transformation in both macaque and baboon, and at secondary implantation sites, preceded trophoblast attachment. In contrast, glandular epithelia in pregnant macaques exhibited a temporal and compartmentalized gradient of Muc-1 loss confined to the implantation sites. Glandular epithelia in the pregnant baboon uterus were uniformly negative for Muc-1. CONCLUSIONS: Restriction of the Muc-1 loss in glandular epithelia to conceptual cycles may reflect the fundamental distinctions among epithelia of the various uterine compartments and the differential modulation of Muc-1 that occurs within these compartments in conceptual and non-conceptual cycles.

show abstract

Section: Discussionmentioning

confidence: 99%

Compartmental distinctions in uterine Muc-1 expression during early pregnancy in cynomolgous macaque (Macaca fascicularis) and baboon (Papio anubis)

Julian¹,

Enders²,

Fazleabas³

et al. 2005

Human Reproduction

View full text Add to dashboard Cite

show abstract

“…The Callithricidae are the only group of higher primates which, as a rule, has multiple births, the majority o f which are dizygotic twins [Wislocki, 1939]. A question still debated is whether twinning in callithricids merely reflects the retention of a primitive mammalian feature [Schultz, 1949[Schultz, , 1969, or whether it developed secondarily after this group of primates had already passed through an earlier evolutionary stage of monovular condition which is still found in all other anthropoid primates [H amlett and W islocki, 1934], How ever, before this complex problem can be dealt with, some basic remarks on the biology of multiple births in primates are needed.…”

Section: Discussionmentioning

confidence: 99%

Maternal-Fetal Weight Relationships in Primates

Leutenegger¹

1973

Folia Primatol

168

View full text Add to dashboard Cite

Analysis of maternal-fetal weight relationships in primates based on the regression equation F (fetal weight) = b · M (maternal weight)^a indicates that prosimian and anthropoid primates are separated by an allometric shift which can be interpreted as a result of differences in placental structures. The regular occurrence of multiple births in both prosimians and anthropoids is limited to small-sized species only, and is considered to be the result of selective pressure against oversized dimensions of the fetus at term to guarantee successful delivery. Twinning in callithricids is demonstrated as having developed secondarily as a byproduct of evolutionary miniaturization, rather than as a retention of a primitive mammalian feature.

show abstract

“…In these species, fraternal twins exchange cell lines through chorionic fusion during early development (2,4,5). On the basis of karyotypic evidence from Callithrix jacchus (2,3), estimates are that 95% of pregnancies result in the birth of hematopoietic chimeric twins.…”

mentioning

confidence: 99%

Germ-line chimerism and paternal care in marmosets ( Callithrix kuhlii )

Ross

French

Ortı́

2007

Proc. Natl. Acad. Sci. U.S.A.

139

View full text Add to dashboard Cite

The formation of viable genetic chimeras in mammals through the transfer of cells between siblings in utero is rare. Using microsatellite DNA markers, we show here that chimerism in marmoset (Callithrix kuhlii) twins is not limited to blood-derived hematopoietic tissues as was previously described. All somatic tissue types sampled were found to be chimeric. Notably, chimerism was demonstrated to be present in germ-line tissues, an event never before documented as naturally occurring in a primate. In fact, we found that chimeric marmosets often transmit sibling alleles acquired in utero to their own offspring. Thus, an individual that contributes gametes to an offspring is not necessarily the genetic parent of that offspring. The presence of somatic and germ-line chimerism may have influenced the evolution of the extensive paternal and alloparental care system of this taxon. Although the exact mechanisms of sociobiological change associated with chimerism have not been fully explored, we show here that chimerism alters relatedness between twins and may alter the perceived relatedness between family members, thus influencing the allocation of parental care. Consistent with this prediction, we found a significant correlation between paternal care effort and the presence of epithelial chimerism, with males carrying chimeric infants more often than nonchimeric infants. Therefore, we propose that the presence of placental chorionic fusion and the exchange of cell lines between embryos may represent a unique adaptation affecting the evolution of cooperative care in this group of primates.callitrichid ͉ genetic chimerism ͉ genomic conflict ͉ social behavior

show abstract

Observations on twinning in marmosets

Cited by 122 publications

References 11 publications

Compartmental distinctions in uterine Muc-1 expression during early pregnancy in cynomolgous macaque (Macaca fascicularis) and baboon (Papio anubis)

Compartmental distinctions in uterine Muc-1 expression during early pregnancy in cynomolgous macaque (Macaca fascicularis) and baboon (Papio anubis)

Maternal-Fetal Weight Relationships in Primates

Germ-line chimerism and paternal care in marmosets ( Callithrix kuhlii )

Contact Info

Product

Resources

About