Observations on the development of Trypanosoma rangeli in the hemocoel of Rhodnius prolixus

Tobie, Eleanor Johnson

doi:10.1016/0022-2011(70)90106-0

Cited by 40 publications

(14 citation statements)

References 6 publications

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“…Apparently, fusion of the host cell lysosomes with the vacuole takes place. Intravacuolar parasites in process of digestion but no dividing parasites are seen within the vacuole (Oliveira & Souza 2003) in contrast to what is observed outside the host cells in the hemolymph, where parasites can intensively multiply (Tobie 1970, Mello et al 1995, Garcia et al 2004a. In addition, during the course of infection, some plasmatocytes appeared disrupted, showing released parasites (Oliveira & Souza 2003).…”

Section: Trypanosoma Rangeli and Hemolymph Interactionsmentioning

confidence: 81%

Trypanosoma rangeli interactions within the vector Rhodnius prolixus: a mini review

Azambuja

Garcia

2005

Mem. Inst. Oswaldo Cruz

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Section: Trypanosoma Rangeli and Hemolymph Interactionsmentioning

confidence: 81%

Trypanosoma rangeli interactions within the vector Rhodnius prolixus: a mini review

Azambuja

Garcia

2005

Mem. Inst. Oswaldo Cruz

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“…These compounds not only block carbohydrates exposed on the parasite surface of but also inhibit the attachment of the T. rangeli in both midgut (Oliveira and de Souza 1997) and salivary glands (Basseri et al 2003). After T. rangeli invasion of the hemolymph from the midgut, the parasites are taken up by the R. prolixus hemocytes and divide therein before escaping and invading the salivary glands (Tobie 1970). It is not clear if the invasion of parasites in the hemocytes is mediated solely by phagocytosis or by active invasion by the parasite in a parasitophorous vacuole.…”

Section: Trypanosoma Rangeli and Vector Interactionsmentioning

confidence: 99%

Towards an understanding of the interactions of Trypanosoma cruzi and Trypanosoma rangeli within the reduviid insect host Rhodnius prolixus

Ratcliffe

Garcia

2005

An. Acad. Bras. Ciênc.

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This review outlines aspects on the developmental stages of Trypanosoma cruzi and Trypanosoma rangeli in the invertebrate host, Rhodnius prolixus. Special attention is given to the interactions of these parasites with gut and hemolymph molecules and the effects of the organization of midgut epithelial cells on the parasite development. The vector insect's permissiveness to T. cruzi, which develops in the vector gut, largely depends on the host nutritional state, the parasite strain and the molecular interactions with trypanolytic compounds, lectins and resident bacteria in the gut. T. rangeli invades the hemocoel and once in the hemolymph, can be recognized and activates the defense system of its insect vector, i.e., the prophenoloxidase system, phagocytosis, hemocyte microaggregation, superoxide and nitric oxide activity and the eicosanoid biosynthesis pathway. Taken together, these findings not only provide a better understanding of the interactions parasite -insect vector, but also offer new insights into basic physiological processes involved in the parasites transmission.

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“…After initial development in the gut, the flagellates penetrate through the gut wall, a route peculiar to this species, and develop in the haemolymph and salivary glands. The triatomine-bugs transmit T. rangeli by inoculation of saliva containing metacyclic forms during feeding or probing (Tobie, 1970 ;Añ ez, 1983 a, b;Hecker, Schwarzenbach & Rudin, 1990).…”

Section: Introductionmentioning

confidence: 99%

Phylogeny, taxonomy and grouping of Trypanosoma rangeli isolates from man, triatomines and sylvatic mammals from widespread geographical origin based on SSU and ITS ribosomal sequences

et al. 2004

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S U M M A R YPhylogenetic relationships among Trypanosoma rangeli isolates from man, wild mammals and triatomine bugs from widespread geographical origin were inferred by comparison of the small subunit of ribosomal gene sequences. The phylogenetic trees indicated that the subgenus Herpetosoma is polyphyletic and strongly supported division of this group into two monophyletic lineages, one made up of T. rangeli, T. rangeli-like and allied species and other consisting of T. lewisi and related taxa. Based on phylogenetic analysis, morphology, behaviour in vertebrate and invertebrate hosts and epidemiology we propose : a) the validation of Herpetosoma as a taxon comprised only for species of group lewisi and the maintenance of T. lewisi as the type-species of this subgenus ; b) the classification of T. rangeli, T. rangeli-like and allied species into a ' T. rangeli-clade ' more closely related to Schizotrypanum than to T. lewisi or T. brucei. The phylogenetic tree disclosed at least 4 groups within the clade T. rangeli, all confirmed by polymorphism of the internal transcribed spacer, thus conferring for the first time phylogenetic support to groups of T. rangeli and corroborating the high complexity of this taxon. Grouping was independent of their mammalian host-species and geographical origin, indicating that other factors are determining this segregation.

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Observations on the development of Trypanosoma rangeli in the hemocoel of Rhodnius prolixus

Cited by 40 publications

References 6 publications

Trypanosoma rangeli interactions within the vector Rhodnius prolixus: a mini review

Trypanosoma rangeli interactions within the vector Rhodnius prolixus: a mini review

Towards an understanding of the interactions of Trypanosoma cruzi and Trypanosoma rangeli within the reduviid insect host Rhodnius prolixus

Phylogeny, taxonomy and grouping of Trypanosoma rangeli isolates from man, triatomines and sylvatic mammals from widespread geographical origin based on SSU and ITS ribosomal sequences

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