nterest in the searching of bibliographic databases by nonlibrarians and noninforrnation specialists has soared in recent years. Currently, library users and other information seekers are being encouraged to satisfy their own information needs directly through the use of a variety of information retrieval systems. These end-user systems are available through online and optical disk technologies and permit access to numerous information resources.It has long been recognized in the field of medicine that rapid and convenient access to current information is critically important. In the 1950s and 1960s, the National Library of Medicine (NLM) developed an automated information retrieval system called MEDLARS (MEDical Literature Analysis and Retrieval System) to facilitate information provision to health care professionals. Currently, MEDLARS contains more than 30 databases of medical and related literature. The largest and most popular of the MEDLARS databases is MEDLINE, which contains more than six million references to the biomedical fiterature from more than 4,000 journals in English and foreign languages. The print Index Medicus is a subset of MEDLINE.With the rise in interest of end-user searching and the need for health care professionals to obtain timely information, it is not surprising that a variety of end-user searching systems for providing access to MEDLARS databases has been developed. 1 One such system that provides access to MEDLINE is an online