Observations of cat leprosy

Ej, Thompson; Pb, Little; Do, Cordes

doi:10.1080/00480169.1979.34660

Cited by 16 publications

(16 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Historically, the causative agent of feline leprosy was reported to be Mycobacterium lepraemurium , a nonzoonotic mycobacterium, known as the agent of leprosy in rodents . Numerous feline leprosy cases have been described around the world (Australia, New Zealand, Canada, UK, USA, The Netherlands, Italy and Greece), mostly in temperate coastal areas and port cities where rats are commonly encountered by cats. In the present study, the definition was extended to cases in which PCR assays identified amplicons characteristic of mycobacteria or cases in which the histology and clinical course were characteristic of feline leprosy, but without molecular identification of the acid‐fast bacilli (AFB) detected within lesions.…”

Section: Introductionmentioning

confidence: 99%

Feline cutaneous mycobacteriosis: a review of clinical, pathological and molecular characterization of one case of Mycobacterium microti skin infection and nine cases of feline leprosy syndrome from France and New Caledonia

Laprie¹,

Duboy²,

Malík

et al. 2013

Veterinary Dermatology

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Feline cutaneous mycobacteriosis: a review of clinical, pathological and molecular characterization of one case of Mycobacterium microti skin infection and nine cases of feline leprosy syndrome from France and New Caledonia

Laprie¹,

Duboy²,

Malík

et al. 2013

Veterinary Dermatology

View full text Add to dashboard Cite

show abstract

“…Gingiva, nasal plane and internal organs may also be involved. The condition occurs in temperate, coastal climates and has been reported in New Zealand, 6,7 Australia, 8–10 Western Canada, 11,12 the Netherlands, 13 UK 14,15 USA, 16 North Italy, 17 and Greece 18 . The causative agent is presumed to be M. lepraemurium ; however, recent studies using the polymerase chain reaction (PCR) have recently demonstrated the presence of other mycobacteria including novel species 9,10,19,20 …”

Section: Introductionmentioning

confidence: 99%

Isolated lepromatous conjunctivo‐corneal granuloma in a cat from Italy

Lamagna

Paciello

Ragozzino

et al. 2009

Veterinary Ophthalmology

View full text Add to dashboard Cite

show abstract

“…Cat leprosy has a widespread geographic distribution (23,28). It was first reported in New Zealand in 1962 (35), and in 1979 the number of recorded cases of cat leprosy was reported to be higher in New Zealand than in any other country (35). de Lisle and colleagues (5) suggested, however, that cases of cat leprosy among cats in the large area in the center of the North Island in New Zealand where bovine tuberculosis is endemic may have been misdiagnosed as cat leprosy.…”

mentioning

confidence: 99%

Determination of the etiology of presumptive feline leprosy by 16S rRNA gene analysis

et al. 1997

View full text Add to dashboard Cite

PCR-amplified 16S rRNA gene sequences were obtained directly from tissue specimens from eight cats with presumptive feline leprosy. Acid-fast bacilli were observed in sections from all eight specimens, but culture for mycobacteria was successful for one specimen only. Analysis of the V2 variable region of each 16S rRNA PCR product identified a sequence with 100% nucleotide identity to the sequences of Mycobacterium lepraemurium, Mycobacterium avium, and Mycobacterium paratuberculosis in four of the specimens from cats with feline leprosy. Separate M. paratuberculosis-and M. avium-specific PCR amplifications of the four specimens were negative, thus substantiating the identification of M. lepraemurium in these specimens from cats with feline leprosy. Further sequence analysis of the V3 variable region of one of the four specimens provided conclusive evidence of the presence of M. lepraemurium. This is the first report of the definitive identification of M. lepraemurium in cats with feline leprosy by molecular biology-based analyses. M. avium, which is rarely reported in cats, and Mycobacterium chitae, a reported nonpathogenic, rapidly growing mycobacterial species found in the environment, were identified in the specimen from which acid-fast bacilli were cultured. Two of the specimens from cats were infected with a potentially novel species of mycobacteria which had a 16S rRNA gene sequence sharing the closest nucleotide sequence identity with that of Mycobacterium malmoense. Molecular biologybased analyses provided for the accurate and rapid diagnosis of mycobacterial infections in cats and circumvented the problems of culture and misdiagnosis of feline leprosy associated with traditional methods.

show abstract

Observations of cat leprosy

Cited by 16 publications

References 4 publications

Feline cutaneous mycobacteriosis: a review of clinical, pathological and molecular characterization of one case of Mycobacterium microti skin infection and nine cases of feline leprosy syndrome from France and New Caledonia

Feline cutaneous mycobacteriosis: a review of clinical, pathological and molecular characterization of one case of Mycobacterium microti skin infection and nine cases of feline leprosy syndrome from France and New Caledonia

Isolated lepromatous conjunctivo‐corneal granuloma in a cat from Italy

Determination of the etiology of presumptive feline leprosy by 16S rRNA gene analysis

Contact Info

Product

Resources

About