The low-energy spectrum of three particles interacting via nearly resonant two-body interactions in the Efimov regime is set by the so-called three-body parameter. We show that the three-body parameter is essentially determined by the zero-energy two-body correlation. As a result, we identify two classes of two-body interactions for which the three-body parameter has a universal value in units of their effective range. One class involves the universality of the three-body parameter recently found in ultracold atom systems. The other is relevant to short-range interactions that can be found in nuclear physics and solid-state physics.The Efimov effect is a universal low-energy quantum phenomenon, which was originally predicted in nuclear physics [1] and has rekindled considerable interest since its experimental confirmation with ultracold atoms . It is also expected to occur in solid-state physics [23,24]. This universality stems from the effective three-body attraction that occurs between particles interacting with nearly resonant short-range interactions. As a result of this attraction, three particles may bind even when the interaction is not strong enough to bind two particles. Furthermore, an infinite series of such three-body bound states exists near the unitary point where the interaction is resonant, i.e. where a two-body bound state appears and the s-wave scattering a length diverges. The typical three-body energy spectrum for such systems is represented in Fig. 1 in units of inverse length. Near zero energy and large scattering lengths, the three-body spectrum is invariant under a discrete scaling transformation by a universal factor e π/s0 ≈ 22.7 for identical bosons, where s 0 ≈ 1.00624 characterises the strength of the three-body attraction.A notable consequence of the Efimov effect is the existence of another physical scale beyond the two-body scattering length to fix the low-energy properties of the system. This scale is known as the three-body parameter. In zero-range models, it manifests itself as the necessity to introduce a momentum cutoff or a three-body boundary condition. It can be characterised, for instance, by the scattering length a − at which a trimer appears or by its binding wave number κ at unitarity, as indicated in Fig. 1. Because of the discrete scaling invariance, it is defined up to a power of e π/s0 . In this Letter, we will focus on the ground Efimov state, which slightly deviates from the discrete-scaling-invariant structure, but is more easily observed and computed, and still reveals the essence of the physics behind the three-body parameter.Three important questions can be raised concerning the three-body parameter. Is there a simple mechanism that determines the three-body parameter from the microscopic interactions? What is the microscopic length scale which determines the three-body parameter? Finally, if there is such a length scale, what are the conditions for the three-body parameter to be related to that length scale through a universal dimensionless constant,