Observation of Efficacy of Internet-Based Chronic Disease Management Model Combined with Modified Therapy of Bushenyiliu Decoction in Treating Patients with Type 2 Diabetes Mellitus and Prostate Cancer and Its Effect on Disease Control Rate

Abstract

Objective. To explore the efficacy of Internet-based chronic disease management model combined with the modified therapy of Bushenyiliu decoction in treating patients with type 2 diabetes mellitus (T2DM) and prostate cancer and its effect on disease control rate (DCR). Methods. 120 patients with T2DM and prostate cancer admitted to the Affiliated Hospital of Yangzhou University, Yangzhou First People’s Hospital, from February 2019 to February 2020, were retrospectively analyzed and equally divided into the experimental group and the control group according to their admission order. Conventional treatment combined with the modified therapy of Bushenyiliu decoction was performed on all patients for 3 months, and the Internet-based chronic disease management model was adopted for patients in the experimental group additionally, so as to compare their short-term effect, survival time, disease progression, blood glucose indicators, immune function indicators, and type 2 Diabetes Self-Care Scale (2-DSCS) scores. Results. Compared with the control group, the experimental group obtained significantly higher DCR and objective remission rate (ORR) ( P < 0.05 ), higher survival time and disease progression ( P < 0.001 ), better blood glucose indicators and immune function indicators ( P < 0.001 ), and higher 2-DSCS scores ( P < 0.001 ) after treatment. Conclusion. Combining the Internet-based chronic disease management model with the modified therapy of Bushenyiliu decoction can effectively enhance the self-care ability of patients with T2DM and prostate cancer, improve their blood glucose level, promote their body immunity, and comprehensively optimize the cancer control effect, which should be promoted in practice.

Developing a Core Outcome Set for Assessing Clinical Safety Outcomes of Prostate Cancer in Clinical Trials of Traditional Chinese Medicine: Protocol for a Mixed Methods Study

“…Prostate cancer is one of the most common malignant tumors affecting male individuals worldwide, posing a threat to patients' health and quality of life [1,33]. However, currently published clinical trials focusing on TCM treatment for prostate cancer have encountered problems related to inconsistent and nonstandard reporting of outcome indicators [11][12][13].…”

“…In recent years, with the in-depth understanding of traditional Chinese medicine (TCM) regarding the etiology, pathogenesis, and treatment of prostate cancer, clinical research on TCM for the treatment of prostate cancer at various stages has gradually increased [9,10]. Numerous clinical trials and systematic reviews have been conducted on TCM or integrative medicine for prostate cancer to improve the efficacy and safety outcomes [11][12][13][14]. However, due to the lack of guidance on a core outcome set (COS), there is obvious heterogeneity in the selection of outcome measures among different studies.…”

Diagnostic Value of Emission Computed Tomography Combined with Computed Tomography for Metastatic Malignant Tumor of Spine

“…At this stage, pathological examination is still the gold standard for testing the nature of spinal tumors, but it is traumatic, and biopsy puncture is not feasible in some patients (such as those with coagulation disorder or poor compliance) [ 5 ], so minimally invasive and convenient imaging tests are gaining attention in clinic. Computed tomography (CT), X-rays, and emission computed tomography (ECT) are all common imaging modalities for the diagnosis of spinal tumors, and among them, X-ray films can clarify the nature of the lesion based on its morphology, presence or absence of bone destruction, etc., but some lesions that appear abnormal on ECT often require months to be visualized on X-ray films [ 6 ], so X-rays are generally used in the initial examination. CT has better sensitivity for the detection of metastatic spine tumors compared to X-rays and is especially valuable for suspected metastatic lesions with X-ray negative and ECT positive, because it is capable of visualizing the involvement of bone trabecula, cortical bone, and surrounding soft tissues.…”