Obliteration of temporal dorsal bulla in guinea pigs using different types of calcium phosphate

Park, Yong-Ho; Kim, Sun Gui; Lee, Jin Woo; Yoon, Young Hoon

doi:10.1016/j.ijporl.2011.06.015

Cited by 6 publications

(5 citation statements)

References 27 publications

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“…β-TCP has been a used widely graft material in dental, cranial, and spinal surgery [ 15 , 16 , 17 , 18 , 19 , 20 ]. In addition, cement type bone graft material, which is composed of β-TCP and polyphosphate, has been used to induce bone regeneration after cranial or spinal surgery [ 12 , 13 , 14 ]. It has also been used as a scaffold because of its high porosity that provides sufficient spaces for newly formed bone to grow after spinal surgery.…”

Section: Discussionmentioning

confidence: 99%

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Bone cement grafting increases implant primary stability in circumferential cortical bone defects

Shin

Kye

Chang

et al. 2015

J Periodontal Implant Sci

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PurposeImplant beds with an insufficient amount of cortical bone or a loss of cortical bone can result in the initial instability of a dental implant. Thus, the objective of this study was to evaluate the effect of bone cement grafting on implant initial stability in areas with insufficient cortical bone.MethodsTwo different circumferential defect depths (2.5 mm and 5 mm) and a control (no defect) were prepared in six bovine rib bones. Fourteen implants of the same type and size (4 mm×10 mm) were placed in each group. The thickness of the cortical bone was measured for each defect. After the implant stability quotient (ISQ) values were measured three times in four different directions, bone cement was grafted to increase the primary stability of the otherwise unstable implant. After grafting, the ISQ values were measured again.ResultsAs defect depth increased, the ISQ value decreased. In the controls, the ISQ value was 85.45±3.36 (mean±standard deviation). In circumferential 2.5-mm and 5-mm defect groups, the ISQ values were 69.42±7.06 and 57.43±6.87, respectively, before grafting. These three values were significantly different (P<0.001). After grafting the bone cement, the ISQ values significantly increased to 73.72±8.00 and 67.88±10.09 in the 2.5-mm and 5.0-mm defect groups, respectively (P<0.05 and P<0.001). The ISQ value increased to more than double that before grafting in the circumferential 5-mm defect group. The ISQ values did not significantly differ when measured in any of the four directions.ConclusionsThe use of bone cement remarkably increased the stability of the implant that otherwise had an insufficient level of stability at placement, which was caused by insufficient cortical bone volume.Graphical Abstract

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Section: Discussionmentioning

confidence: 99%

“…After approximately seven weeks, the commencement of absorption can be identified. Bone cement is commonly employed in orthopedic surgery and neurosurgery [ 12 , 13 , 14 ]. The ideal hardening time of bone cement is less than 5 minutes, and this reaction is not an exothermic reaction.…”

Section: Introductionmentioning

confidence: 99%

Bone cement grafting increases implant primary stability in circumferential cortical bone defects

Shin

Kye

Chang

et al. 2015

J Periodontal Implant Sci

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“…The bone cement was composed of β-tricalcium phosphate and polyphosphate (macropores: 100–500 µm. micropores: <10 µm, porosity: 60%–70%), in a blend mainly used for cranial and spinal surgery [171819]. The working time of this material is about 4 minutes and hardening is completed in 7 minutes.…”

Section: Methodsmentioning

confidence: 99%

Primary stability of implants with peri-implant bone defects of various widths: an in vitro investigation

Yim

Lim

Hong

et al. 2019

J Periodontal Implant Sci

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Purpose This study aimed to evaluate the effects of i) the extent of peri-implant bone defects and ii) the application of bone cement on implant stability with respect to the measurement direction. Methods In 10 bovine rib bones, 4 implant osteotomies with peri-implant bone defects of various widths were prepared: i) no defect (D0), ii) a 2-mm-wide defect (D2), iii) a 4-mm-wide defect (D4), and iv) a 8-mm-wide defect (D8). The height of all defects was 10 mm. Implant stability quotient (ISQ) values and Periotest values (PTVs) were measured after implant placement and bone cement application. Results With increasing defect width, decreased ISQs and increased PTVs were observed. Statistically significant differences were found between groups D0 and D8, D0 and D4, and D2 and D8. Prior to bone cement application, inconsistent PTVs were found in group D8 depending on the measurement direction. Bone cement increased the implant stability. Conclusion Peri-implant bone deficits measuring around 50% of the implant surface compromised implant stability. Clinically, PTVs should be cautiously interpreted in implants with large peri-implant defects due to inconsistent recordings with respect to the measurement direction.

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“…In one study, the granule type of PolyBone® was more effective than the powder type in the obliteration of bullae in guinea pigs [28]. They commented that the granule type produced relatively low inflammatory reactions and obvious new bone formation with biodegraded graft materials.…”

Section: Discussionmentioning

confidence: 99%

Clinical Significance of β-Tricalcium Phosphate and Polyphosphate for Mastoid Cavity Obliteration during Middle Ear Surgery: Human and Animal Study

Lee

Lim

Cho

et al. 2013

Clin Exp Otorhinolaryngol

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ObjectivesMastoid obliteration is used to obliterate the mastoid cavity following a mastoidectomy or to prevent the formation of a retraction pocket. This study evaluated the effectiveness of β-tricalcium phosphate and polyphosphate (β-TPP) for mastoid obliteration in middle ear surgeries in prospective human and animal studies.MethodsTwenty patients with chronic otitis media underwent mastoid obliteration using β-TPP after a intact canal wall mastoidectomy or simple mastoidectomy. The clinical data were prospectively evaluated including: the diagnosis, temporal bone computed tomography (TBCT), otoscopic findings, pure tone audiogram, and complications. In the animal experiment, β-TPP was applied into the right bulla in five rats, and the opposite bulla was used as the control in the non-obliterated state. The skulls of five other rats were drilled out and the holes were obliterated with β-TPP. TBCT were obtained at 3, 6, and 9 months after the obliteration and histologic analysis was done at 3 and 9 months after surgery.ResultsIn the human study, fourteen TBCTs were obtained at 12 months after the surgery. All demonstrated no bone resorption in the obliterated mastoids. Among the 15 cases displaying retracted tympanic membranes preoperatively, 11 showed no retraction, 2 showed retraction postoperatively, 1 was lost to follow-up and 1 was a case of postoperative wound infection. Among 20 cases, one case developed a postoperative infection that necessitated a second operation. Sixteen underwent ossiculoplasty; hearing improvements were obtained in 15 cases and 1 case showed decreased hearing. In the animal study, new bone formation without significant bone resorption in the radiologic and histologic findings were noted in both the skull and bulla groups.ConclusionAlthough β-TPP is a foreign material having the possibility of infection, mastoid obliteration with it can be a treatment option in middle ear surgeries to prevent retraction pockets or the recurrence of diseases.

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Obliteration of temporal dorsal bulla in guinea pigs using different types of calcium phosphate

Cited by 6 publications

References 27 publications

Bone cement grafting increases implant primary stability in circumferential cortical bone defects

Bone cement grafting increases implant primary stability in circumferential cortical bone defects

Primary stability of implants with peri-implant bone defects of various widths: an in vitro investigation

Clinical Significance of β-Tricalcium Phosphate and Polyphosphate for Mastoid Cavity Obliteration during Middle Ear Surgery: Human and Animal Study

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