Objective Measures of Visual Function in Papilledema

Moss, Heather E.

doi:10.1016/j.yaoo.2016.03.004

Cited by 5 publications

(3 citation statements)

References 34 publications

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“…3 Again, this was one of the reasons that motivated the name change from VIIP to SANS. To gain more insight, electrophysiological testing targeting the pattern electroretinogram 4 and photopic negative response 5 of the ganglion cell are planned as part of future NASA-funded research studies. Thus, as NASA has limited experience with long-duration space missions, it may take some time to understand if there are any long-term functional changes to astronaut vision.…”

Section: Sansmentioning

confidence: 99%

Gravitational Influence on Intraocular Pressure: Implications for Spaceflight and Disease

Huang

Stenger

Macias

2019

Journal of Glaucoma

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Spaceflight-associated neuro-ocular syndrome (SANS) describes a series of morphologic and functional ocular changes in astronauts first reported by Mader and colleagues in 2011. SANS is currently clinically defined by the development of optic disc edema during prolonged exposure to the weightless (microgravity) environment, which currently occurs on International Space Station (ISS). However, as improvements in our understanding of the ocular changes emerge, the definition of SANS is expected to evolve. Other ocular SANS signs that arise during and after ISS missions include hyperopic shifts, globe flattening, choroidal/retinal folds, and cotton wool spots. Over the last 10 years, ~1 in 3 astronauts flying long-duration ISS missions have presented with ≥1 of these ocular findings. Commensurate with research that combines disparate specialties (vision biology and spaceflight medicine), lessons from SANS investigations may also yield insight into ground-based ocular disorders, such as glaucomatous optic neuropathy that may have the potential to lessen the burden of this irreversible cause of vision loss on Earth.

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Section: Sansmentioning

confidence: 99%

Gravitational Influence on Intraocular Pressure: Implications for Spaceflight and Disease

Huang

Stenger

Macias

2019

Journal of Glaucoma

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“…In IIH, Demyelination of the optic nerve may be a more likely mechanism similar to compression neuropathy that occurs in the peripheral nerves. (11) . Our findings come in agreement with that reported by Sureda et al and Kesler et al, who reported abnormally delayed VEP latencies in IIH patients with normal amplitudes and attributed the optic nerve dysfunction in IIH to demyelination except in cases with secondary axonal loss.…”

Section: Discussionmentioning

confidence: 99%

Small check size pattern reversal visual evoked potentials (VEPs) in patients with chronic idiopathic intracranial hypertension

Alim

Elhabashy

Hussein

et al. 2022

ijhs

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The condition known as idiopathic intracranial hypertension is characterized by elevated intracranial pressure. The most feared complication of IIH is visual loss due to papilledema and optic nerve atrophy. Visual evoked potentials are sensitive and non-invasive method. They are considered an important objective test in investigating suspected optic nerve disease. This study aims to clarify the effect of chronic increased ICP on the optic nerve. Methods: This case-control study was performed at Beni-Suef University Hospital on 60 female patients divided into two equal groups; Group (I): thirty female patients with chronic idiopathic hypertension and Group (II): thirty age and sex-matched healthy controls. All subjects were subjected to full neuro-ophthalmological assessment by PVEP, a lumbar puncture to measure CSF pressure, and radiological assessment using MRI. SPSS version 20 was used for the statistical analysis. Results: Right Pattern reversed VEP; for the check size 15min, the mean value of P100 latencies of chronic IIH was 109.88±10.46 and for controls was 97.35±4.23. The mean value of P100 amplitudes of chronic IIH was 11.73±5 and for controls was 11.95±3.3. Left pattern reversed VEP; for the check size 15min, the mean value of P100 latencies of chronic IIH was 111.42±11.5 and for controls was 97.13±4.32.

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“…Dynamic visual field testing (eg, Goldmann kinetic visual fields) is useful in patients who are unable to fully cooperate with automated perimetry testing, such as younger children or those with neurological deficits 31. If formal visual field testing is not possible, there are other objective measures of visual function which have been proposed as techniques to monitor vision in patients with papilledema 32. These tests include visual evoked potentials (VEP), pattern electroretinogram (ERG), and full-field ERG.…”

Section: Neuro-ophthalmological Manifestationsmentioning

confidence: 99%

<p>Neuro-ophthalmological manifestations of tuberous sclerosis: current perspectives</p>

Wan

Chan²,

Jastrzembski

et al. 2019

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Tuberous sclerosis complex (TSC) is a complex, multi-system disorder with a well-described underlying genetic etiology. While retinal findings are common in TSC and important in establishing the diagnosis, TSC also has many potential neuro-ophthalmology manifestations. The neuro-ophthalmology manifestations of TSC can have a significant impact on visual function and are sometimes a sign of serious neurological disease. The purpose of this review is to describe the neuro-ophthalmological manifestations of TSC. These manifestations include optic nerve hamartomas, elevated intracranial pressure, cranial nerve palsies, cortical visual impairment, visual field deficits, and ocular toxicity from vigabatrin treatment of infantile spasms. It is important to be aware of potential neuro-ophthalmological manifestations in these patients in order to detect signs of vision- or life-threatening disease and to optimize visual function and quality-of-life.

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Objective Measures of Visual Function in Papilledema

Cited by 5 publications

References 34 publications

Gravitational Influence on Intraocular Pressure: Implications for Spaceflight and Disease

Gravitational Influence on Intraocular Pressure: Implications for Spaceflight and Disease

Small check size pattern reversal visual evoked potentials (VEPs) in patients with chronic idiopathic intracranial hypertension

<p>Neuro-ophthalmological manifestations of tuberous sclerosis: current perspectives</p>

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