Objective evaluation of through-focus optical performance of presbyopia-correcting intraocular lenses using an optical bench system

Kim, Myoung Joon; Zheleznyak, Len; MacRae, Scott; Tchah, Hungwon; Yoon, Geunyoung

doi:10.1016/j.jcrs.2011.03.033

Cited by 77 publications

(67 citation statements)

References 30 publications

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“…Maxwell et al 6 and Kim et al 7 presented the imaging of a USAF target through multifocal IOLs. Such characterization is more representative for the quality of the patient's retinal image than MTF measurement alone and crosscorrelation curves.…”

Section: Resultsmentioning

confidence: 99%

Clinically Relevant Optical Properties of Bifocal, Trifocal, and Extended Depth of Focus Intraocular Lenses

Gatinel¹,

Loicq

2016

J Refract Surg

121

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ultifocal intraocular lenses (IOLs) with two or more foci can be used to replace the opacified natural lens during routine cataract surgery. They are recommended by cataract surgeons as the replacement lenses of choice when patients wish to avoid wearing spectacles. However, some patients implanted with multifocal IOLs report glare and halos at night, and the assessment of the objective optical quality of these lenses deserves interest.Differences in the design of diffractive IOLs translate into differences in optical quality at their foci, through-focus performance, and halo features, which can offer further information to surgeons when selecting which IOL to implant. In addition to being objective and patient independent, optical bench testing of multifocal IOLs has the ability to control factors that are difficult to address in clinical essays such as pupil diameter, lens alignment and tilt, and level of corneal spherical aberration on the multifocal IOL.The International Organization for Standardization (ISO) standards 11979-2 and 11979-9 define the guidelines for the in vitro measurement of the optical quality of an IOL. Optical bench evaluation of the modulation transfer function (MTF) provides valuable information about the optical quality of IOLs. [1][2][3] The correlations existing between a trifocal IOL, a varifocal IOL, and a monofocal IOL using the "ex vivo" optical bench through-focus image quality analysis and the clinical visual performance in real patients by study of the defocus curve were investigated. Significant correlations were found between logMAR visual acuity and image quality metric for the multifocal and monofocal IOLs analyzed. Ex vivo find-M ABSTRACT PURPOSE: To experimentally compare the optical performance of three types of hydrophobic intraocular lenses (IOLs): extended depth of focus, bifocal, and trifocal. METHODS:The tested IOLs were: TECNIS ZMB00 (bifocal; Abbott Medical Optics, Abbott Park, IL), TECNIS Symfony ZXR00 (extended depth of focus; Abbott Medical Optics), and FineVision GFree hydrophobic (trifocal; PhysIOL, Liège, Belgium). Their surface topography was analyzed by optical microscopy. Modulation transfer function (MTF) and spherical aberrations were determined on optical bench for variable pupil apertures and with two cornea models (0 µm and +0.28 µm). United States Air Force target imaging was analyzed for different focal points (near, intermediate, and far). Point spread function (PSF) and halos were quantified and compared. RESULTS:The three lenses presented step-like optic topography. For a pupil size of 3 mm or greater, clearly distinctive MTF peaks were observed for all lenses: two peaks for the extended depth of focus and bifocal lenses with +1.75 and +4.00 diopters (D) addition, respectively, and three peaks for the trifocal lens with +1.75 and +3.50 addition for intermediate and near vision, respectively. The extended depth of focus and bifocal lens had slightly higher MTF at best focus with the +0.28 µm cornea model than with the 0 µm model, whereas the tri...

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Section: Resultsmentioning

confidence: 99%

Clinically Relevant Optical Properties of Bifocal, Trifocal, and Extended Depth of Focus Intraocular Lenses

Gatinel¹,

Loicq

2016

J Refract Surg

121

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“…Multifocal optical corrections are becoming popular solutions for compensation of presbyopia, aiming at providing the patient with a range of focus for functional vision at near without compromising far vision (Cochener, Lafuma, Khoshnood, Courouve, & Berdeaux, 2011;Kim, Zheleznyak, Macrae, Tchah, & Yoon, 2011;Lichtinger & Rootman, 2012). In the current study we have evaluated, optically (ideal observer) and psychophysically, the quality provided by six radial and angularly segmented multiple zone multifocal phase patterns.…”

Section: Discussionmentioning

confidence: 99%

Testing vision with angular and radial multifocal designs using Adaptive Optics

et al. 2017

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Multifocal vision corrections are increasingly used solutions for presbyopia. In the current study we have evaluated, optically and psychophysically, the quality provided by multizone radial and angular segmented phase designs. Optical and relative visual quality were evaluated using 8 subjects, testing 6 phase designs. Optical quality was evaluated by means of Visual Strehl-based-metrics (VS). The relative visual quality across designs was obtained through a psychophysical paradigm in which images viewed through 210 pairs of phase patterns were perceptually judged. A custom-developed Adaptive Optics (AO) system, including a Hartmann-Shack sensor and an electromagnetic deformable mirror, to measure and correct the eye's aberrations, and a phase-only reflective Spatial Light Modulator, to simulate the phase designs, was developed for this study. The multizone segmented phase designs had 2-4 zones of progressive power (0 to +3D) in either radial or angular distributions. The response of an "ideal observer" purely responding on optical grounds to the same psychophysical test performed on subjects was calculated from the VS curves, and compared with the relative visual quality results. Optical and psychophysical pattern-comparison tests showed that while 2-zone segmented designs (angular & radial) provided better performance for far and near vision, 3-and 4-zone segmented angular designs performed better for intermediate vision. AO-correction of natural aberrations of the subjects modified the response for the different subjects but general trends remained. The differences in perceived quality across the different multifocal patterns are, in a large extent, explained by optical factors. AO is an excellent tool to simulate multifocal refractions before they are manufactured or delivered to the patient, and to assess the effects of the native optics to their performance.

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“…The 2-D image correlation coefficient is equal to unity when the two compared images are identical. This metric is known to be reliable in evaluating the visual performance [10].…”

Section: Through-focus Optical Quality Metricsmentioning

confidence: 99%

Temporal multiplexing to simulate multifocal intraocular lenses: theoretical considerations

Akondi

Dorronsoro

Gambra

et al. 2017

Biomed. Opt. Express

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Fast tunable lenses allow an effective design of a portable simultaneous vision simulator (SimVis) of multifocal corrections. A novel method of evaluating the temporal profile of a tunable lens in simulating different multifocal intraocular lenses (M-IOLs) is presented. The proposed method involves the characteristic fitting of the through-focus (TF) optical quality of the multifocal component of a given M-IOL to a linear combination of TF optical quality of monofocal lenses viable with a tunable lens. Three different types of M-IOL designs are tested, namely: segmented refractive, diffractive and refractive extended depth of focus. The metric used for the optical evaluation of the temporal profile is the visual Strehl (VS) ratio. It is shown that the time profiles generated with the VS ratio as a metric in SimVis resulted in TF VS ratio and TF simulated images that closely matched the TF VS ratio and TF simulated images predicted with the M-IOL. The effects of temporal sampling, varying pupil size, monochromatic aberrations, longitudinal chromatic aberrations and temporal dynamics on SimVis are discussed.

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Objective evaluation of through-focus optical performance of presbyopia-correcting intraocular lenses using an optical bench system

Cited by 77 publications

References 30 publications

Clinically Relevant Optical Properties of Bifocal, Trifocal, and Extended Depth of Focus Intraocular Lenses

Clinically Relevant Optical Properties of Bifocal, Trifocal, and Extended Depth of Focus Intraocular Lenses

Testing vision with angular and radial multifocal designs using Adaptive Optics

Temporal multiplexing to simulate multifocal intraocular lenses: theoretical considerations

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