Objective Assessment of Venous Pulse Wave Velocity in Healthy Humans

Ermini, Leonardo; Ferraresi, Carlo; Benedictis, Carlo De; Roatta, Silvestro

doi:10.1016/j.ultrasmedbio.2019.11.003

Cited by 13 publications

(16 citation statements)

References 19 publications

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“…Edge tracking algorithms can be applied to peripheral veins to investigate, by ultrasound, the mechanical response to changes in transmural pressure, e.g., by venous occlusion, for the assessment of venous compliance (47,48) and characterize the filling condition and the expanding capacity of the peripheral reservoir, a major pathway for venous return. Assessment of venous compliance could also be used to validate another recently proposed index of peripheral vascular filling, the venous pulse wave velocity (49,50). Combining these methods with the IVC assessment might increase the understanding of the underlying mechanisms of fluid distribution and displacements across different body regions and compartments in various clinical contexts (28,29).…”

Section: Current and Future Applicationsmentioning

confidence: 99%

Assessment of Phasic Changes of Vascular Size by Automated Edge Tracking-State of the Art and Clinical Perspectives

Mesin

Albani

Policastro

et al. 2022

Front. Cardiovasc. Med.

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Assessment of vascular size and of its phasic changes by ultrasound is important for the management of many clinical conditions. For example, a dilated and stiff inferior vena cava reflects increased intravascular volume and identifies patients with heart failure at greater risk of an early death. However, lack of standardization and sub-optimal intra- and inter- operator reproducibility limit the use of these techniques. To overcome these limitations, we developed two image-processing algorithms that quantify phasic vascular deformation by tracking wall movements, either in long or in short axis. Prospective studies will verify the clinical applicability and utility of these methods in different settings, vessels and medical conditions.

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Section: Current and Future Applicationsmentioning

confidence: 99%

Assessment of Phasic Changes of Vascular Size by Automated Edge Tracking-State of the Art and Clinical Perspectives

Mesin

Albani

Policastro

et al. 2022

Front. Cardiovasc. Med.

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“…Nowadays, the estimation of volaemic status (or volaemia) of a patient through a noninvasive method is not trivial but its development could be of great utility, given that interest in the patient's volaemic spans across several different hospital departments [1]. An innovative method for assessing the volaemic status of patients has recently been proposed: pulse wave velocity in veins, termed venous pulse wave velocity (vPWV) [2,3]. The relation among vPWV, venous pressure, and changes in blood volume was first observed in the 1970s [4,5], but the methodology was subsequently abandoned, possibly due to the difficulty of achieving reliable measurements.…”

Section: Introductionmentioning

confidence: 99%

“…The incremental elastic modulus is proportional to the filling of the vessel. In case of veins, their filling should be a good proxy of the volaemic status of the subject, with veins being the capacitance vessels that are used as a blood volume reservoir [2]. PWV measurement is considerably easier in the arteries than in the veins due to higher blood pressure in the arteries and the presence of a natural cardiac pulsatility that is absent in veins.…”

Section: Introductionmentioning

confidence: 99%

“…In some subjects, backward pulsatility related to right atrium contractions can be observed; in others flow, is almost constant. Sending an exogenous compression synchronised with cardiac and respiratory activity allows for the measurement to be applicable and repeatable over a large pool of subjects, regardless of whether they have inherent pulsatility [2,3]. It was thus possible to measure vPWV with reasonable reliability and to confirm linear correlation between vPWV and venous pressure [2].…”

Section: Introductionmentioning

confidence: 99%

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A Portable Device for the Measurement of Venous Pulse Wave Velocity

et al. 2022

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Pulse wave velocity in veins (vPWV) has recently been reconsidered as a potential index of vascular filling, which may be valuable in the clinic for fluid therapy. The measurement requires that an exogenous pressure pulse is generated in the venous blood stream by external pneumatic compression. To obtain optimal measure repeatability, the compression is delivered synchronously with the heart and respiratory activity. We present a portable prototype for the assessment of vPWV based on the PC board Raspberry Pi and equipped with an A/D board. It acquires respiratory and ECG signals, and the Doppler shift from the ultrasound monitoring of blood velocity from the relevant vein, drives the pneumatic cuff inflation, and returns multiple measurements of vPWV. The device was tested on four healthy volunteers (2 males, 2 females, age 33±13 years), subjected to the passive leg raising (PLR) manoeuvre simulating a transient increase in blood volume. Measurement of vPWV in the basilic vein exhibited a low coefficient of variation (3.6±1.1%), a significant increase during PLR in all subjects, which is consistent with previous findings. This device allows for carrying out investigations in hospital wards on different patient populations as necessary to assess the actual clinical potential of vPWV.

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“…Lower extremity venous pulsed-wave Doppler already has been shown to correlate with central venous pressure. 6 Femoral vein Doppler is not without its nuances and challenges. Invasive monitors and lines, mechanical support devices, and extracorporeal membrane oxygenation cannulae occupying the patient's femoral vessels can make vein assessment technically impossible.…”

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confidence: 99%