Obesity, reproduction and oxidative stress

Abstract

The prevalence of obesity and overweight is one of the most pressing problems nowadays. Obesity as a comorbid condition affects all body systems. Obesity has been reported to be a risk factor not only for cardiovascular diseases and oncopathology, but also for fertility problems, many obstetric and perinatal complications worsening the maternal and infant health. The balance between the oxidative and antioxidant system is one of the indicators of the state of human homeostasis. Today it is proved that obesity is associated with an increase in oxidative stress and a decrease in antioxidant protection. This review reveals a close relationship between obesity, oxidative stress and reproductive problems.

Oxidative Stress in Endometrial Pathology in Women of Reproductive Age

“…Накопление эндотоксинов в организме взаимосвязано с дисбалансом в активности свободнорадикального перекисного окисления липидов (ПОЛ) и системы их обезвреживания -антиоксидантной защиты (АОЗ) [6,9,13]. Если эти процессы уравновешены сложным комплексом регуляции, организм остается здоровым, а при поломке этой системы регуляции развивается так называемый окислительный стресс (ОС) [15,17,18].…”