Obesity: Its Relationship to Osteoarthritis of the Knee

Objective. To evaluate the cardiovascular fitness of a group of patients with severe osteoarthritis (OA).Methods. Thirty-seven patients with end-stage OA were evaluated just before hip or knee replacement surgery. Severity of arthritis was evaluated using standardized techniques. Patients and age-and sex-matched controls underwent a single, maximal, symptomlimited, cardiopulmonary exercise test using arm or leg ergometry and a metabolic cart to measure expired respiratory gases.Results. Severe musculoskeletal disability and deformity was confirmed in the OA patient group. During exercise testing, OA patients were able to perform physiologically maximal cardiopulmonary exercise. Arthritis patients were noted to be severely deconditioned, with reduced peak oxygen consumption (OA hips mean f SD 14.9 f 4.2 versus control hips 19.0 f 4.6, P < 0.0001; OA knees 12.8 f 3.7 versus control knees 17.6 2 5.2 ml/kg/minute, P < 0.0005). A trend for more frequent manifestations of coronary heart disease in OA patients than in controls (27% versus 13%; P > 0.05) was also noted.Conclusion. Patients with end-stage lower extremity OA are severely deconditioned. This may place them at incremental risk for the development of coronary heart disease.Previous studies have shown that patients with chronic osteoarthritis (OA) and rheumatoid arthritis ~-Supported by grants from the Stephen C. Clark Foundation (grants 261-91 and 282-92), the E.

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“…17.6 kg versus 70.0 5 12.5 kg; P < 0.001). This finding is consistent with the known relationship between obesity and OA (35)(36)(37).…”

Section: Resultssupporting

confidence: 92%

Cardiovascular fitness and health in patients with end‐stage osteoarthritis

Philbin

Groff

Ries

et al. 1995

Arthritis & Rheumatism

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“…7,10,33 By comparison, little or no attention has been given to the influence of body weight on the foot and ankle. Hartz et al 34 suggested that mechanical stress resulting from obesity was the principal cause for the strong link between obesity and osteoarthritis.…”

Section: Discussionmentioning

confidence: 99%

Plantar pressure differences between obese and non-obese adults: a biomechanical analysis

et al. 2001

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OBJECTIVE:To investigate plantar pressure differences between obese and non-obese adults during standing and walking protocols using a pressure distribution platform. SUBJECTS: Thirty-five males (age 42.4 AE 10.8 y; 67 -179 kg) and 35 females (age 40.0 AE 12.6 y; 46 -150 kg) divided into obese (body mass index (BMI) 38.75 AE 5.97 kg=m 2 ) and non-obese (BMI 24.28 AE 3.00 kg=m 2 ) sub-groups, respectively. MEASUREMENTS: Data collection was performed with a capacitive pressure distribution platform with a resolution of 2 sensors=cm 2 (Emed F01, Novel GmbH, München). The measurement protocol included half and full body weight standing on the left, right and both feet, respectively, and walking across the platform, striking with the right foot. Pressures were evaluated for eight anatomical sites under the feet. RESULTS: For both men and women, the mean pressure values of the obese were higher under all anatomical landmarks during half body weight standing. Significant increases in pressure were found under the heel, mid-foot and metatarsal heads II and IV for men and III and IV for women. Foot width during standing was also significantly increased in obese subjects. For walking, significantly higher peak pressures were also found in both obese males and females. CONCLUSION: Compared to a non-obese group, obese subjects showed increased forefoot width and higher plantar pressures during standing and walking. The greatest effect of body weight on higher peak pressures in the obese was found under the longitudinal arch of the foot and under the metatarsal heads. The higher pressures for obese women compared to obese men during static weight bearing (standing) may be the result of reduced strength of the ligaments of the foot.

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“…This is because a number of studies have reported that obesity is related to a variety of musculoskeletal disorders ranging from osteoarthritis (in both the knee and hip) to joint pain (Bray, 1985;Colditz, 1992;Jung, 1997;Pi-Sunyer, 1993). For example, the greater prevalence of osteoarthritis with increasing body weight has been reported in several cross-sectional studies (Goldin et al, 1976;Leach et al, 1973). It has been reported that a 6-10 kg weight loss in morbidly obese subjects is associated with a relief from pain in the lower back, ankles, and feet (McGoey et al, 1990).…”

Section: Significance Of Musculoskeletal Disordersmentioning

confidence: 99%

The association between musculoskeletal disorders and obesity

Kortt

Baldry²

2002

Aust. Health Review

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The aim of this study was to examine the association between musculoskeletal disorders and the level of obesity (as defined by the body mass index) for a sample of the Australian population aged 20-64. A logistic regression model was used to estimate the association between musculoskeletal disorders and obesity, controlling for a range of socio-demographic characteristics. Individual-level data on obesity, musculoskeletal disorders, and various socio-demographic characteristics were extracted from the Australian Bureau of Statistics (ABS) 1995 National Health Survey (NHS). Individuals with musculoskeletal disorders were identified using ICD-9 codes 710-739 from a sample of 28,376 individuals from the non-institutionalised population. Estimates from the logistic regression equation indicate that there is a statistically significant positive relationship between the probability of having a musculoskeletal disorder and the level of obesity. Socio-demographic variables such as age, sex, origin, income level, employment status and geographic location also had a statistically significant relationship. This information can be used by public health practitioners and educators to identify those at risk and to design health strategies that target at-risk patients.

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Obesity: Its Relationship to Osteoarthritis of the Knee

Cited by 127 publications

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Cardiovascular fitness and health in patients with end‐stage osteoarthritis

Cardiovascular fitness and health in patients with end‐stage osteoarthritis

Plantar pressure differences between obese and non-obese adults: a biomechanical analysis

The association between musculoskeletal disorders and obesity

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