Obesity in the geriatric population – a global health perspective

Malenfant, Jason H; Batsis, John A.

doi:10.29392//001c.11984

Cited by 8 publications

(14 citation statements)

References 7 publications

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“…Obesity trends are also rising, and the increasing prevalence of over the next 20-30 years will place a substantial strain on the finances and resources of the United States healthcare system (2) . These trends have also been observed worldwide (3) . The prevalence of obesity in combination with sarcopenia, the age-related loss of muscle mass and strength, increases in adults aged 65 years and older (4) .…”

Section: Body Composition: Obesity: Older Adults: Sarcopeniasupporting

confidence: 69%

Linking epidemiology and molecular mechanisms in sarcopenic obesity in populations

Bizri

Batsis

2020

Proc. Nutr. Soc.

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Recognising the adverse outcomes that occur to obese adults over the age of 65 years with loss of muscle mass or strength, or sarcopenia is important. We will review the definitions of sarcopenic obesity, and attempt to link the epidemiological data with the molecular pathways. Upon understanding the model of sarcopenic obesity, we will discuss targeted interventions and further challenges to address this geriatric syndrome. As our understanding of this syndrome is growing, more data are emerging to help define sarcopenic obesity across different populations. We now have a better understanding of biological pathways in ageing such as changes in body composition, sex-specific hormones, pro-inflammatory markers and myocellular mechanisms. We will review a comprehensive model that shows the interactions between the different pathways leading to sarcopenic obesity. Such a model will explain the promising interventions in place and invite future ones. Sarcopenic obesity is an important geriatric syndrome with significant clinical and healthcare implications. Further research is needed to harmonise definitions, clarify mechanisms contributing to syndrome and use evidence-based interventions to target biological mechanisms in both research and clinical settings.

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Section: Body Composition: Obesity: Older Adults: Sarcopeniasupporting

confidence: 69%

Linking epidemiology and molecular mechanisms in sarcopenic obesity in populations

Bizri

Batsis

2020

Proc. Nutr. Soc.

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“…7 While there has been a decrease in obesity-related mortality in recent years, likely due to declining cardiovascular mortality, 8 there has been an increase in obesity-related disability. 7 Before this change, obesity rates in older adults, were relatively low and overlooked 9,10 ; thus, less is known about the association between obesity and MM and their impact on function in individuals over age 60 years.…”

Section: Introductionmentioning

confidence: 99%

The relationship between multimorbidity, obesity and functional impairment in older adults

Lynch

Petersen

Fanous

et al. 2022

J American Geriatrics Society

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Background Declining mortality rates and an aging population have contributed to increasing rates of multimorbidity (MM) in the United States. MM is strongly associated with a decline in physical function. Obesity is an important risk factor for the development of MM, and its prevalence continues to rise. Our study aimed to evaluate the associations between obesity, MM, and rates of functional limitations in older adults. Methods We analyzed body mass index (BMI) and self‐reported comorbidity data from 7261 individuals aged ≥60 years from the National Health and Nutrition Examination Surveys 2005–2014. Weight status was defined based on standard BMI categories. MM was defined as 2 or more comorbidities, while functional limitations were self‐reported. Adjusted logistic regression quantified the association between standard BMI categories and MM. We also examined the difference in the prevalence of limitations between those with and without MM. Results The overall proportion of individuals with concomitant MM and obesity was 27.0%. Compared to a normal BMI, older adults with obesity had higher odds of MM (Prevalence odds ratio 1.79, 95% CI 1.49, 2.12). Overall, 67.5% of patients with MM also reported a functional limitation, with rates of functional limitation increasing with increasing BMI. When evaluating functional limitations in those with MM by BMI class, 90% of patients classified as severely obese (BMI ≥40 kg/m2) with MM also had a concomitant functional limitation. Conclusions Compared to normal weight status, obesity is associated with an increased burden of MM and functional limitation among older adults. Our results underscore the importance of identifying and addressing obesity, MM, and functional limitation patterns and the need for evidence‐based interventions that address all three conditions in this population.

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“…7 Both disorders are associated with negative health consequences, such as premature mortality, increased risk of falls, poor physical functioning, comorbidity burden, and reduced quality of life, increasing the risk of loss of independence and institutionalization. [8][9][10] The recommended first-line therapies for (sarcopenic) obesity in older adults are lifestyle interventions aiming at the loss of body weight and fat mass and consist of diet modifications, increasing physical activity or specific exercise training, and behavioural therapy. 11,12 Reviews and guidelines on obesity treatment in older adults have been published suggesting that lifestyle interventions in older adults are effective in reducing body weight and favoring combined interventions including dietary and exercise components.…”

Section: Introductionmentioning

confidence: 99%

Outcomes addressed in randomized controlled lifestyle intervention trials in community‐dwelling older people with (sarcopenic) obesity—An evidence map

et al. 2022

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Obesity and sarcopenic obesity (SO) are characterized by excess body fat with or without low muscle mass affecting bio-psycho-social health, functioning, and subsequently quality of life in older adults. We mapped outcomes addressed in randomized controlled trials (RCTs) on lifestyle interventions in community-dwelling older people with (sarcopenic) obesity. Systematic searches in Medline, Embase, Cochrane Central, CINAHL, PsycInfo, Web of Science were conducted. Two reviewers independently performed screening and extracted data on outcomes, outcome domains, assessment

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Obesity in the geriatric population – a global health perspective

Cited by 8 publications

References 7 publications

Linking epidemiology and molecular mechanisms in sarcopenic obesity in populations

Linking epidemiology and molecular mechanisms in sarcopenic obesity in populations

The relationship between multimorbidity, obesity and functional impairment in older adults

Outcomes addressed in randomized controlled lifestyle intervention trials in community‐dwelling older people with (sarcopenic) obesity—An evidence map

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