Obesity, Diabetes, and Other Cardiovascular Risk Factors in Native Populations of South America

Ingaramo, Roberto A.

doi:10.1007/s11906-015-0613-6

Cited by 16 publications

(10 citation statements)

References 19 publications

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“…These changes are comparable to those affecting Native Americans in the second half of the 20th century, during which important sociocultural changes led to a dramatic increase in chronic diseases (Young, 1997). In Latin America, other native populations also experienced similar changes, and they currently exhibit a high prevalence of obesity and, in some cases, type 2 diabetes mellitus (Ingaramo, 2016).…”

Section: Discussionmentioning

confidence: 75%

Anthropometric and metabolic profile of a Brazilian Amerindian group: The Xikrin (Mebengôkre)

Barbosa

Sacuena

Pinto

et al. 2019

American J Hum Biol

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Objectives: The purpose of this study was to describe the metabolic and anthropometric profile of the Xikrin (Mebengôkre), an indigenous group. Methods: A total of 363 subjects (55.1% women) aged 18 years or older were evaluated. The variables analyzed were age, body weight and height, waist circumference, blood pressure, fasting blood glucose, triglyceride level, and total cholesterol level. Results: A high prevalence of obesity (36.5%) and central obesity (88.1%), mainly among women (46.9% and 96.2%, respectively), was found among the Xikrin (Mebengôkre). Impaired fasting glycemia and diabetes were found in 4.5% and 3.8% of adults, respectively. Twenty-one percent of adults had dyslipidemia and 9.3% had hypertension. Conclusions: The high prevalence of excess weight (overweight and obesity) and central obesity, especially in women, was the most significant finding of this study among the Xikrin (Mebengôkre).

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Section: Discussionmentioning

confidence: 75%

Anthropometric and metabolic profile of a Brazilian Amerindian group: The Xikrin (Mebengôkre)

Barbosa

Sacuena

Pinto

et al. 2019

American J Hum Biol

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“…Recent studies in human and animal models have suggested that validating ICD coding with imaging data could make a strong study [69,73,80,81], as these studies address the issue of possible coding errors. Second, the obesity-DDD association from this study should be interpreted with caution, since it does not reject the “reverse causality” hypothesis (the spinal conditions could increase the risk for obesity as juvenile disc degeneration was strongly associated with diminished physical functioning [6] and diminished physical functioning could mean less energy expenditure). Moreover, with available evidence suggesting a likely relationship between increased BMI and a variety of pain conditions, the question remains as to whether the link we identified here was specific to spinal conditions [82].…”

Section: Discussionmentioning

confidence: 99%

“…Ogden et al [3] reported that the prevalence of obesity in the U.S. was 36.5% among adults and 17% among children and youth during 2011–2014. Obesity is associated with many prevalent conditions including prostate disease [4], cardiovascular diseases [5], diabetes [6], and osteoarthritis [7,8]. A number of studies have found a consistent association between obesity and low back pain (LBP) [9,10,11,12,13].…”

Section: Introductionmentioning

confidence: 99%

Associations between Obesity and Spinal Diseases: A Medical Expenditure Panel Study Analysis

Sheng

Feng

Zhang

et al. 2017

IJERPH

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Background: The link between body weight status and spinal diseases has been suggested by a number of cross-sectional and cohort studies with a limited range of patient populations. No population-representative samples have been used to examine the link between obesity and spinal diseases. The present study is based on a nationally representative sample drawn from the Medical Expenditure Panel Survey. Methods: Using the cross-sectional sample of the 2014 Medical Expenditure Panel Study, we built four weighted logistic regression analyses of the associations between body weight status and the following four spinal diseases: low back pain, spondylosis, other cervical disorders and intervertebral disc disorder (IDD). Each respondent’s body weight status was used as the key independent variable with three categories: normal/underweight, overweight, and obese. We controlled for marital status, gender, age, smoking status, household income, health insurance coverage, educational attainment and the use of health services for other major categories of diseases. Results: A total sample of 23,048 respondents was used in our analysis. Overweight and obese respondents, as compared to normal/underweight respondents, were more likely to develop lower back problems (Overweight: logged odds = 0.218, p < 0.01; Obese: logged odds = 0.395, p < 0.001) and IDD (Overweight: logged odds = 0.441, p < 0.05; Obese: logged odds = 0.528, p < 0.001). The associations between bodyweight status and spondylitis were statistically insignificant (Overweight: logged odds = 0.281, p = 0.442; Obese: logged odds = 0.680, p = 0.104). The associations between body weight status and other cervical disorders (Overweight: logged odds = −0.116, p = 0.304; Obese: logged odds = −0.160, p = 0.865) were statistically insignificant. Conclusions: As the first study using a national sample to study bodyweight and spinal diseases, our paper supports the hypothesis that obesity adds to the burden of low back pain and IDD. Longitudinal and interventional studies are needed to understand the specific mechanisms behind these positive associations.

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“…Atherosclerosis and associated cardiovascular diseases (CVD) represent the major cause of death and comorbidities in Western and developing countries [ 1 , 2 ]. The Global Burden of Disease Study estimated that about 32% of all deaths worldwide in 2013 were caused by CVD, with about 80% of these deaths occurring in low-and middle-income countries [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Role of the APOE polymorphism in carotid and lower limb revascularization: A prospective study from Southern Italy

et al. 2017

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BackgroundAtherosclerosis is a complex multifactorial disease and the apolipoprotein E (APOE) polymorphism has been associated to vascular complications of atherosclerosis.ObjectivesTo investigate the relationship between the APOE genotypes and advanced peripheral vascular disease.Materials and methods258 consecutive patients (201 males and 57 females, mean age 70.83 ± 7.89 years) with severe PVD were enrolled in a 42-months longitudinal study (mean 31.65 ± 21.11 months) for major adverse cardiovascular events. At follow-up genotypes of the APOE polymorphism were investigated in blinded fashion.ResultsAs compared with ε3/ε3, in ε4-carriers a significant higher incidence of major adverse cardiovascular events (35.58% vs. 20.79%; p = 0.025) and total peripheral revascularization (22.64% vs. 5.06%; p < 0.001) was observed. Prospective analysis, showed that ε4-carriers have an increased hazard ratio for major adverse cardiovascular events (adjusted HR 1.829, 95% CI 1.017–3.287; p = 0.044) and total peripheral revascularization (adjusted HR = 5.916, 95% CI 2.405–14.554, p <0.001).ConclusionsThe ε4 allele seems to be risk factor for major adverse cardiovascular events, and in particular for total peripheral revascularization in patients with advanced atherosclerotic vascular disease.

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Obesity, Diabetes, and Other Cardiovascular Risk Factors in Native Populations of South America

Cited by 16 publications

References 19 publications

Anthropometric and metabolic profile of a Brazilian Amerindian group: The Xikrin (Mebengôkre)

Anthropometric and metabolic profile of a Brazilian Amerindian group: The Xikrin (Mebengôkre)

Associations between Obesity and Spinal Diseases: A Medical Expenditure Panel Study Analysis

Role of the APOE polymorphism in carotid and lower limb revascularization: A prospective study from Southern Italy

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