Obesity and worsening of chronic venous disease and joint mobility

Belczak, Cleusa Ema Quilici; Godoy, José María Pereira de; Belzack, Sergio Quilici; Ramos, Rubiana Neves; Caffaro, Roberto Augusto

doi:10.1177/0268355513492510

Cited by 14 publications

(16 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This group of patients was targeted because they have the highest risk of developing VLUs, especially those with stage 5 CVI. These individuals tend to be older, obese and female; older age and higher BMI are risk factors for developing the disease, with an increased incidence of developing VLUs . Our findings are in contrast; more men developed VLUs than women and were younger.…”

Section: Discussioncontrasting

confidence: 69%

Does cryotherapy improve skin circulation compared with compression and elevation in preventing venous leg ulcers?

Kelechi

Mueller

Madisetti

et al. 2016

International Wound Journal

View full text Add to dashboard Cite

This trial compared skin blood flow, temperature and incidence of venous leg ulcers in patients with chronic venous disease using compression wraps and elevation pillows. Patients with CEAP C4 skin damage and C5 history of ulcers were randomly assigned to a cryotherapy intervention (n = 138) or placebo cuff control (n = 138) applied to the lower legs over 9 months. The time the ulcers healed prior to enrollment in the study for the cryotherapy group ranged from 1 to 2218 days (n = 8, median = 32 days); for the control group, the range was 24 to 489 days (n = 6, median = 390 days). There were no statistically significant blood flow changes measured in perfusion units with a laser Doppler flowmetre within or between the groups; mean difference between the groups was 0·62, P = 0·619. No differences were noted in skin temperature measured with an infrared thermometer within and between the groups; mean difference between the groups was −0·17°C, P = 0·540. Cryotherapy did not improve skin blood flow or temperature and did not show efficacy in preventing ulcers. However, at least 30% of intervention and 50% of control participants were anticipated to develop an ulcer during the study; only ∼7% occurred. These findings suggest that strict adherence to standard of care decreases the incidence of leg ulcers and remains a best practice for leg ulcer prevention.

show abstract

Section: Discussioncontrasting

confidence: 69%

Does cryotherapy improve skin circulation compared with compression and elevation in preventing venous leg ulcers?

Kelechi

Mueller

Madisetti

et al. 2016

International Wound Journal

View full text Add to dashboard Cite

show abstract

“…Part of the difficulty in understanding this relationship stems from the multifaceted nature of the two variables. For instance, the weight of excess adiposity restricts joint and muscle mobility and increases joint pain, which may make it more difficult for people to move (Belczak et al, 2014 ; Muramoto et al, 2014 ). However, weight alone does not appear sufficient to explain physical inactivity in people with obesity.…”

Section: Obesity and Physical Inactivitymentioning

confidence: 99%

Do Dopaminergic Impairments Underlie Physical Inactivity in People with Obesity?

Kravitz

O’Neal

Friend

2016

Front. Hum. Neurosci.

View full text Add to dashboard Cite

Obesity is associated with physical inactivity, which exacerbates the negative health consequences of obesity. Despite a wide consensus that people with obesity should exercise more, there are few effective methods for increasing physical activity in people with obesity. This lack is reflected in our limited understanding of the cellular and molecular causes of physical inactivity in obesity. We hypothesize that impairments in dopamine signaling contribute to physical inactivity in people with obesity, as in classic movement disorders such as Parkinson's disease. Here, we review two lines of evidence supporting this hypothesis: (1) chronic exposure to obesogenic diets has been linked to impairments in dopamine synthesis, release, and receptor function, particularly in the striatum, and (2) striatal dopamine is necessary for the proper control of movement. Identifying the biological determinants of physical inactivity may lead to more effective strategies for increasing physical activity in people with obesity, as well as improve our understanding of why it is difficult for people with obesity to alter their levels of physical activity.

show abstract

“…These factors lead to vein damage, venous insufficiency, and/or CVD. [14][15][16] VLUs are the most common type of lower extremity ulcer, accounting for >70% of all types of ulcers, including those with an arterial or neuropathic/diabetic etiology, or a combination of etiologies. 17 Approximately 50% of VLUs are chronic, failing to proceed through an orderly reparative process for timely healing of the anatomic or functional injury.…”

Section: Pathophysiologymentioning

confidence: 99%

Chronic venous disease and venous leg ulcers: An evidence-based update

Kelechi

Johnson

Yates

2015

Journal of Vascular Nursing

View full text Add to dashboard Cite

Obesity and worsening of chronic venous disease and joint mobility

Abstract: Obesity is associated with deterioration in joint mobility and worsening of chronic venous disease.

Cited by 14 publications

References 12 publications

Does cryotherapy improve skin circulation compared with compression and elevation in preventing venous leg ulcers?

Does cryotherapy improve skin circulation compared with compression and elevation in preventing venous leg ulcers?

Do Dopaminergic Impairments Underlie Physical Inactivity in People with Obesity?

Chronic venous disease and venous leg ulcers: An evidence-based update

Contact Info

Product

Resources

About