Obesity and Viral Infections

Jaisinghani, Priya

doi:10.1016/j.gtc.2023.03.012

Cited by 4 publications

(4 citation statements)

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“…The higher risk of thrombosis and respiratory dysfunction due to altered respiratory mechanisms contributed to increased risk in obese patients. 35 Moreover, it had been proposed that obesity is a pro-inflammatory disease, and inflammatory markers in COVID-19 admitted patients had been significantly associated with serious illness and mortality. 32 , 35 , 36 Similarly, it was unsurprising that immunocompromised, CKD, and chronic respiratory diseases patients were at high risk.…”

Section: Discussionmentioning

confidence: 99%

“… 35 Moreover, it had been proposed that obesity is a pro-inflammatory disease, and inflammatory markers in COVID-19 admitted patients had been significantly associated with serious illness and mortality. 32 , 35 , 36 Similarly, it was unsurprising that immunocompromised, CKD, and chronic respiratory diseases patients were at high risk. A persistent pro-inflammatory state, elevated expression of ACE2 and TMPRSS2, airflow limitation, and use of corticosteroids would lead to an increased risk of hospitalization and severe illness.…”

Section: Discussionmentioning

confidence: 99%

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Impact of COVID-19 vaccination status on hospitalization and disease severity: A descriptive study in Nagasaki Prefecture, Japan

Cai,

Liu,

et al. 2024

Human Vaccines & Immunotherapeutics

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Coronavirus disease 2019 (COVID-19) was extraordinarily harmful, with high rates of infection and hospitalization. This study aimed to evaluate the impact of COVID-19 vaccination status and other factors on hospitalization and disease severity, using data from Nagasaki Prefecture, Japan. Confirmed cases of COVID-19 infection with vaccination status were included and the differences in characteristics between different vaccination statuses, hospitalization or not, and patients with varying levels of disease severity were analyzed. Furthermore, logistic regression was used to calculate odds ratio (ORs) and 95% confidence intervals (CI) to evaluate the association of various factors with hospitalization and disease severity. From March 14, 2020 to August 31, 2022, 23,139 patients were unvaccinated 13,668 vaccinated the primary program with one or two doses, and 4,575 completed the booster. Vaccination reduced the risk of hospitalization with an odd ratio of 0.759 (95% CI: 0.654–0.881) and the protective effect of completed booster vaccination was more pronounced (OR: 0.261, 95% CI: 0.207–0.328). Similarly, vaccination significantly reduced the risk of disease severity (vaccinated primary program: OR: 0.191, 95% CI: 0.160–0.228; completed booster vaccination: OR: 0.129, 95% CI: 0.099–0.169). Overall, unvaccinated, male, elderly, immunocompromised, obese, and patients with other severe illness factors were all risk factors for COVID-19-related hospitalization and disease severity. Vaccination was associated with a decreased risk of hospitalization and disease severity, and highlighted the benefits of completing booster.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Impact of COVID-19 vaccination status on hospitalization and disease severity: A descriptive study in Nagasaki Prefecture, Japan

Cai,

Liu,

et al. 2024

Human Vaccines & Immunotherapeutics

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“…These cut-off values are based on statistical analysis, and it has been shown that living at the extremes of appropriate nutrition, thinness, and overweight/obesity increases the likelihood of acquiring chronic illnesses with serious negative effects on the general public health [30]- [33]. Given that obesity is linked to greater rates of infectious complications, more severe viral infections, and increased death rates owing to subpar vaccination responses, it may have a negative impact on immunological responses [34]- [39].…”

Section: Introductionmentioning

confidence: 99%

Relationship between BMI and CD4 cell counts among people living with HIV on ART attending Infectious Disease Hospital, Kano State

David

Isyaku²,

Etukudo³

et al. 2023

Preprint

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Background There are currently an estimated 38 million people living with HIV (PLWHIV) in the globe. The aim of the present study was to examine the relationship between Body mass index (BMI) and CD4 cell counts among people living with HIV attending Infectious Disease Hospital, Kano State. Method Two hundred HIV-positive and non-HIV positive above 18 years of age were recruited for the study. Blood samples were collected from both categories for the determination of CD4 count. The relationship between the height, weight, BMI, and CD4 cell counts was examined using Pearson correlation, and a p-value less than 0.05 was considered statistically significant. Result Mean heights of among male HIV subject (1.66 ± 0.07) was significantly higher (p < 0.001) compared to female HIV subjects (1.54 ± 0.09). BMI was significantly higher (p < 0.001) in female HIV subjects (24.74 ± 4.95) when compared to male HIV subjects (21.78 ± 2.73). There was a moderate positive correlation (r = 0.280, p = 0.006) between CD4 cell count and height in non-HIV males; however, there was no significant correlation between CD4 count and BMI in HIV and non-HIV individuals. Conclusion The study concludes that there exists sexual dimorphism in HIV subjects among people living with HIV. There was no significant relationship between CD4 cell count and BMI in HIV and non-HIV individuals.

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“…Estudiar la salud y la enfermedad en los grupos humanos implica abordar el consumo de alimentos. Basta observar la relación consistente entre los patrones alimentarios y la prevención, ocurrencia o agravamiento de patologías de gran prevalencia mundial tales como la diabetes tipo II, el cáncer y las enfermedades cardiovasculares (Wang et al, 2023); o bien, advertir cómo entre 1975 y 2016 la alimentación fue el factor fundamental en la triplicación de la prevalencia mundial de obesidad (OMS, 2021) y que esta morbilidad propicia otras enfermedades crónicas e incrementa la vulnerabilidad y virulencia en infecciones como la COVID-19 (Jaisinghani & Kumar, 2023;Tadayon et al, 2023).…”

Section: Introductionunclassified

La Subordinación Real del Consumo bajo el Capital como teoría específica para estudiar los fenómenos alimentarios contemporáneos

Hernández Ramírez

2023

pacha

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La teoría de la Subordinación Real del Consumo bajo el Capital formulada por Jorge Veraza explica cómo la extensión del capitalismo hacia la producción, distribución y comercialización de los alimentos ha determinado la configuración de las dietas actuales. Si bien existen otras teorías ampliamente usadas para dar cuenta de los fenómenos alimentarios contemporáneos, su poder explicativo es insuficiente porque, en el contexto del mercado capitalista mundial, evitan analizar la forma capitalista de producir alimentos y sus implicaciones directas en el deterioro del valor de uso alimentario. Así, el objetivo de este artículo es caracterizar el modelo teórico de la Subordinación Real del Consumo bajo el Capital (modelo SRCC) y examinar su claridad y poder explicativo respecto a los fenómenos alimentarios contemporáneos. Se describen los elementos principales del modelo SRCC, aplicados al ámbito de la alimentación humana; asimismo, se examinan su claridad (definiciones conceptuales) y poder explicativo (grado de confirmación empírica y profundidad de los enunciados), recurriendo eventualmente a comparaciones con el modelo teórico de las plantas de civilización formulado por Braudel y con el de la transición nutricional propuesto por Popkin. El modelo SRCC está ligado a la teoría del desarrollo capitalista de Karl Marx, a la cual enriquece y desarrolla con hipótesis específicas sobre el dominio fáctico del consumo y con aportes del psicoanálisis y del estudio de la cultura; asimismo, se adecua suficientemente a las evidencias disponibles sobre patrones de alimentación en contextos eminentemente capitalistas y permite realizar inferencias lógicas profundas para explicar los respectivos mecanismos subyacentes.

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Obesity and Viral Infections

Cited by 4 publications

References 66 publications

Impact of COVID-19 vaccination status on hospitalization and disease severity: A descriptive study in Nagasaki Prefecture, Japan

Impact of COVID-19 vaccination status on hospitalization and disease severity: A descriptive study in Nagasaki Prefecture, Japan

Relationship between BMI and CD4 cell counts among people living with HIV on ART attending Infectious Disease Hospital, Kano State

La Subordinación Real del Consumo bajo el Capital como teoría específica para estudiar los fenómenos alimentarios contemporáneos

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