Purpose To describe the prevalence of overweight and obesity among diVerent occupational groups and sectors in a representative sample of the Dutch working population, and to test whether these diVerences still exist after adjustment for socio-demographic variables. Methods Cross-sectional data among 7,588 working adults were used. Univariate analyses of variance was performed to test diVerences in body mass index (BMI) values between occupational groups (n = 7) and sectors (n = 28). Adjusted analyses were carried out to examine the role of socio-demographic factors in the diVerences in overweight and obesity between occupational groups and sectors. Results On average, the mean BMI was 24.3 kg/m 2 with 31% being overweight and 6% being obese. Those working in trade, industrial, or transportation occupations as well as the legislators and senior managers had the highest BMI and a relatively high prevalence of overweight (36.7 and 35.5%, respectively) and obesity (6.9 and 7.5%, respectively). In contrast, those working in scientiWc and artistic professions had the most favorable BMI proWle with 25.7% being overweight and 4.2% being obese. After adjusting for sex, age, and education, the proportion of variance changed from about 0.01 to 0.10 with age being the main contributor of the diVerences in overweight and obesity. Conclusions BMI proWle and prevalence of overweight and obesity diVers between occupations and sectors.Despite the diVerences are explained partly by socio-demographic factors, based on a given distribution of age, sex, and education within each occupational group and sector, occupational group-and sector-speciWc strategies to prevent and reduce overweight are recommended.