Obesity and Clozapine use in Schizophrenia

O Retinoblastoma é um tumor maligno característico da infância, o que antes era sinal de enucleação, desde 2005 vem sendo aplicado um tratamento inovador com a quimioterapia intra-arterial que constatou ser efetivo, trazendo bom controle do tumor e complicações sistêmicas mínimas. Pesquisas apresentam resultados de efetividade e segurança desta terapêutica utilizada em alguns países, assim como os principais fármacos utilizados e os resultados positivos no tratamento do retinoblastoma. As informações foram obtidas através de um estudo de revisão na literatura científica, onde se verificou que os fármacos mais utilizados na quimioterapia intra-arterial são o melfalano, a carboplatina e o topotecano. A partir destes resultados podemos concluir que o fármaco de primeira escolha é o melfalano, que pode ser usado em monoterapia ou combinado com carboplatina ou topotecano. Atualmente ainda há estudos em andamento que avaliam a efetividade e segurança do topotecano e da carboplatina na pediatria, sejam em monoterapia ou terapia combinada com outros antineoplásicos.

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A Closed Form Solution for a One-Dimensional Multi-Layered Neutron Transport Problem by Analytical Discrete Ordinates Method

Filho

Rodrigues

2017

DDF

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In this work, the Analytical Discrete Ordinates Method (ADO method) is used to provide a closed form solution for a class of one-dimensional neutron transport problems in Cartesian geometry, considering heterogeneous media with linearly anisotropic scattering effects. In this context, the mathematical model will describe a steady-state phenomenon, with neutron sources located inside and on the boundaries of the domain of interest. In the process, the integro-differential transport equation is transformed into an ODE system by the SN angular discretization, which homogeneous solution is obtained with a quadratic eigenvalues problem with reduced order. A particular solution in terms of constants is used. To validate the code, the method and provide benchmark results, test problems will be treated and results will be discussed.

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Obesity and Clozapine use in Schizophrenia

Cited by 8 publications

References 13 publications

Mental Health Nurses' Knowledge of Clozapine

Mental Health Nurses' Knowledge of Clozapine

Estudo de revisão de efetividade e segurança dos fármacos utilizados na Quimioterapia Intra-arterial no Tratamento do Retinoblastoma

A Closed Form Solution for a One-Dimensional Multi-Layered Neutron Transport Problem by Analytical Discrete Ordinates Method

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