Obesity and asthma at school entry: Co‐morbidities and temporal trends

James, Santhamma; Pezic, Angela; Ponsonby, Anne–Louise; Lafferty, Antony; Glasgow, Nicholas; Ciszek, Karen; Kljakovic, Marjan; Douglas, Kirsty

doi:10.1111/jpc.12160

Cited by 9 publications

(3 citation statements)

References 31 publications

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“…The mean asthma prevalence across the seven years included in the present analysis was 11%, with a higher prevalence evident in boys and overweight/obese participants relative to girls and normal weight participants, respectively. This association between obesity and asthma is in accord with previous studies (Black et al 2012;Figueroa-Muñoz et al 2001;Gennuso et al 1998;Luder et al 1998), as is the gender difference (Anthracopoulos et al 2011;Hansen et al 2013;James et al 2013).…”

Section: Discussionsupporting

confidence: 92%

The relationship between body mass index, aerobic performance and asthma in a pre-pubertal, population-level cohort

2013

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Section: Discussionsupporting

confidence: 92%

The relationship between body mass index, aerobic performance and asthma in a pre-pubertal, population-level cohort

2013

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“…A total of 1473 studies were identified whereof 355 were duplicates and 1025 were excluded on titles and abstract, leaving 93 papers for full text evaluation. Of these, 24 original studies, two meta‐analyses and one additional study from the manual search of references were included 8,14‐39 (Figure ).…”

Section: Resultsmentioning

confidence: 99%

Association between childhood asthma and attention deficit hyperactivity or autism spectrum disorders: A systematic review with meta‐analysis

Kaas

Vinding

Stokholm

et al. 2020

Clin Experimental Allergy

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Background: Children with asthma are at risk of depression and anxiety and growing evidence suggest they may also be at risk of attention deficit hyperreactivity disorder (ADHD) and autism spectrum disorder (ASD). Here, we conducted a systematic review with meta-analysis of studies investigating association between asthma and ADHD or ASD in children. Methods: A comprehensive search using PubMed, EMBASE and Cochrane Library databases was completed in March 2019. Observational human studies published in English, clinic-based or population-based with a healthy comparator group, evaluating asthma-ADHD or asthma-ASD overlap in children 18 years or younger using categorical diagnoses (yes/no) were considered for inclusion. Random effects metaanalysis models were used to analyse data. The Newcastle Ottawa Scale was used to evaluate risk of bias. Results: A total of 25 asthma-ADHD studies were included of which 17 showed significant positive associations and one a negative association: 17/25 studies were population-based, 19/25 were cross-sectional or cohort studies and 7/25 had a low risk of bias. We performed a meta-analysis of 23 of the studies, which showed a significant association between asthma and ADHD: odds ratio (OR) 1.52 (1.42-1.63), P < .001, I2 = 60%. All studies were adjusted for age and sex and a large proportion; that is, 19/23 were further adjusted for relevant confounders. Seventeen asthma-ASD studies were included, whereof 7 showed a positive association and 3 a negative association; 8/17 were population-based with a cross-sectional study design and 4/17 had a low risk of bias. We performed a meta-analysis of 14 of the studies, which did not show a significant association between asthma and ASD: OR 1.12 (0.93-1.34), P = .24, I2 = 89%. All studies were adjusted for age and sex and 10/14 were further adjusted for relevant confounders. Conclusions: This systematic review with meta-analyses shows a significant overlap between asthma and ADHD, but not between asthma and ASD in children. Clinicians taking care of children with asthma or ADHD should be aware of such association to aid an early diagnosis and treatment of such comorbidity. | 229 KAAS et Al.

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“…After review of the titles and abstracts, 536 articles did not meet our inclusion criteria, and 12 were excluded 31-42 for a lack of data for the frequency of AD/eczema or BMI classification. In total, 30 studies 26,33, were included in the review, of which 20 had valid data that could be pooled to assess for the effects of overweight, 26,43,47,50,[53][54][55][56][57][59][60][61][62][63][64][65][66][67][68][69] 23 for obesity, 26,33,43,45,47,50,[52][53][54][55][56][57][59][60][61][62][63][64][65][66][67][68][69] and 26 for overweight/obesity. 26,43,44,[46]…”

Section: Literature Searchmentioning

confidence: 99%

Association of atopic dermatitis with being overweight and obese: A systematic review and metaanalysis

Zhang

Silverberg

2015

Journal of the American Academy of Dermatology

241

213

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Obesity and asthma at school entry: Co‐morbidities and temporal trends

Cited by 9 publications

References 31 publications

The relationship between body mass index, aerobic performance and asthma in a pre-pubertal, population-level cohort

The relationship between body mass index, aerobic performance and asthma in a pre-pubertal, population-level cohort

Association between childhood asthma and attention deficit hyperactivity or autism spectrum disorders: A systematic review with meta‐analysis

Association of atopic dermatitis with being overweight and obese: A systematic review and metaanalysis

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