O078 : The prevalence and mortality of acute-on-chronic liver failure defined by APASL vs. EASL-CLIF Consortium: A multicenter, retrospective cohort study in Korea (kaclif study)

Clinical assessments of health status as a potential marker to identify patients who are too sick to undergo transplantation

“…However, if a patient's physiological reserve is insufficient to withstand an acute decompensation event, acute decompensation often leads to acute‐on‐chronic liver failure with high short‐term mortality . In our multicenter retrospective study, 28‐day mortality was 32% in patients with acute‐on‐chronic liver failure . In this respect, incorporation of a standardized clinician assessment of health into the MELD score will help to screen patients with cirrhosis who are very frail that have a low likelihood of benefit from LT, improving waitlist mortality and providing an opportunity for appropriate interventions.…”