O-GlcNAcylation: Crosstalk between Hemostasis, Inflammation, and Cancer
Itzel Patricia Vásquez Martínez,
Eduardo Pérez-Campos,
Laura Pérez-Campos Mayoral
et al.
Abstract:O-linked β-N-acetylglucosamine (O-GlcNAc, O-GlcNAcylation) is a post-translational modification of serine/threonine residues of proteins. Alterations in O-GlcNAcylation have been implicated in several types of cancer, regulation of tumor progression, inflammation, and thrombosis through its interaction with signaling pathways. We aim to explore the relationship between O-GlcNAcylation and hemostasis, inflammation, and cancer, which could serve as potential prognostic tools or clinical predictions for cancer pa… Show more
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