O Acometimento Orovalvar Em Pacientes Com Lúpus Eritematoso Sistêmico: Uma Revisão Sistemática

Abstract

BACKGROUNDThe systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple organs being, between the systemic diseases, the one with the greatest cardiovascular impact. The cardiac involvement can involve the valves, pericardium, myocardium and predisposition to coronary artery disease. The orovalvar alterations are caused by the deposition of immunoglobulins and the complement occurs at the end of the clinical curse of the disease and the absent of active states. The objective of this study was to verify the prevalence of valvar diseases in patients with SLE. METHODSSystematic revision of literature realized between June and July 2021, in the databases of PubMed, LILACS and Google Scholar. The health sciences descriptors were "aortic valve diseases" and "lupus erythematosus", cross-checked by the Boolean operator AND. According to the PRISMA guidelines, this study included transversals works that approached the prevalence of valve diseases and that was published between 2016 and 2021.