O‐3
Assessment of the tripath focal point™ slide profiler as a quality assurance tool within the cervical screening programme in wales

Abstract

The use of computer assisted screening (CAS) in cervical screening is established in the USA and Europe and is currently undergoing trials in the UK (HTA). Following the introduction of SurePath™ LBC technology to Wales, Cervical Screening Wales (CSW) has implemented a study into applications of CAS within the CSP in Wales, agreed during LBC procurement negotiations. Technological support was provided by TriPath Europe and Medical Solutions UK Ltd. Evaluation centred on the use of CAS in Quality Assurance procedures, comparing it with rapid screening (review and preview), as HTA studies are already established to assess the primary screening role. Assessment included • Evaluation of CAS across a laboratory network – assessing sample identification, tracking processes and transportation • Assessment of Quintile Ranking verses abnormality distribution • Assessment of the NFR (no further review) category as a reliable indicator of sample negativity • Monitoring screener performance using CAS: Focal Point/LGS has the capability to monitor operator/observer functions Three laboratories in North Wales participated in the study. Slides were scanned centrally using Focal Point LGS and returned to laboratories for assessment. Slide assessment followed a twin track protocol. • The ‘manual’ arm assessed slides according to standard laboratory procedures • The ‘CAS’ arm assessed slides using location guidance and screening Data were collected and analysed by CSW. Approximately 12 000 samples were scanned; results were compared for both arms. Results show that the technology has a number of benefits, in supporting and enhancing performance within the screening programme. • CAS compares favourably with rapid screening • Quintile ranking data reflects the distribution of abnormalities • The technology is well suited to shared use through laboratory networks • Variations in screener aptitude were noted.