Abstract:hemorrhagic stroke. In this study, we analyzed protein expression signature in human CCM tissue samples by using highly specific and sensitive multiplexing technique, proximity extension assay (PEA) in Olink platform. Methods Relative expression of 184 biomarkers were analyzed from fresh-frozen CCM lesion samples (n=6; age 3-66 years; male:female ratio 2:4) and brain tissue controls from normal cerebral cortex (n=3; age 34-69 years; male:female ratio 2:1; Amsbio, Abington, UK) using Olink Target 96 Cardiovascu… Show more
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