Nycthemeral variation in thermal dehydration-induced thirst

Barney, Christopher C.; Vergoth, Carol; Renkema, Lori-ann; Meeuwsen, Kenneth W.

doi:10.1016/0031-9384(95)00059-r

Cited by 5 publications

(5 citation statements)

References 24 publications

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“…Acute heat exposure also caused an increase in feces output as previously reported (Barney et al. ). The increased feces output is a stress response (Bonaz and Taché ; Morrow and Garrick ; Banji et al.…”

Section: Discussionsupporting

confidence: 81%

“…, ; Barney and West ; Barney and Folkerts ; Barney et al. , ) and has been attributed to the removal of the osmotic drive to drink by returning plasma osmolality and sodium concentration to control levels prior to ingestion of water equal to the water losses (Nose et al. , ; Barney and West ; Barney ).…”

Section: Discussionmentioning

confidence: 99%

“…Water intake following heat exposure was increased in the dark phase of the light cycle compared to the light phase (Barney et al. ). In another experiment water intake was increased in spontaneously hypertensive rats compared to their normotensive controls (Barney et al.…”

Section: Introductionmentioning

confidence: 99%

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Heat acclimation and thirst in rats

et al. 2015

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The effects of heat acclimation on water intake and urine output responses to thermal dehydration and other thirst stimuli were studied in male Sprague–Dawley rats. Rats were heat acclimated by continuous exposure to a 34°C environment for at least 6 weeks. Thermal dehydration‐induced thirst was brought about by exposing the heat‐acclimated rats and control rats housed at 24°C to a 37.5°C environment for 4 h without access to food or water. Heat acclimation reduced evaporative and urinary water losses and the increases in plasma sodium and osmolality during thermal dehydration, which led to a reduction in thermal dehydration‐induced thirst. Heat acclimation reduced the rate of rehydration following thermal dehydration but did not alter the final rehydration level, indicating that heat acclimation does not alter the primary control of thermal dehydration‐induced thirst. Heat acclimation did not alter water intake or urine output following administration of hypertonic saline, which selectively stimulates intracellular thirst, but led to greater water intake following administration of angiotensin II, which plays an important role in extracellular/volemic thirst, and following water deprivation, which activates both thirst pathways. Cardiovascular responses to angiotensin II were not altered by heat acclimation. Heat acclimation thus reduces water loss during heat exposure in rats, but does not have major effects on thermal dehydration‐induced or extracellular thirst but does appear to alter volemic thirst.

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Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 99%

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Heat acclimation and thirst in rats

et al. 2015

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“…Heat exposure increased urine output and sodium excretion in both WKY and SH rats as previously shown for Sprague-Dawley strain rats (4,5). The increase in urine output during heat exposure is due to an as-yet-unexplained diuresis that occurs during the first hour of exposure to the heat (5).…”

Section: R1306supporting

confidence: 69%

Thermal dehydration-induced thirst in spontaneously hypertensive rats

Barney

Smith

Folkerts

1999

American Journal of Physiology-Regulatory, Integrative and Comp

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Spontaneously hypertensive (SH) rats and normotensive Wistar-Kyoto (WKY) rats were exposed to either 25 or 37.5°C for 3.5 h, and their thermal and water balance responses were compared. After exposure, either a blood sample was obtained or the rats were allowed to rehydrate for 4 h. SH rats had both higher core temperatures and evaporative water losses during heat exposure. Measurements of hematocrit, hemoglobin concentration, plasma protein and sodium concentrations, and plasma osmolality indirectly showed that the SH rats were dehydrated relative to the WKY rats after exposure to either 25 or 37.5°C. SH rats drank significantly more water but also had significantly higher urine volumes than the WKY rats and thus rehydrated only slightly better than the WKY rats. SH and WKY rats had similar levels of water intake and urine output after 24 h of water deprivation. The elevated thermal response of SH rats to heat exposure does not appear to lead to uncompensatable changes in body water status.

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“…In this study, both groups of rats had low levels of urine output during the recovery period, similar to previous studies (Grace and Stevenson ; Barney and West ; Barney et al. ). It is not clear why the increase in urine output observed during exposure seen in the IH w rats did not continue during the recovery period, since these rats were less dehydrated and presumably had lower AVP levels than the IH w/o rats.…”

Section: Discussionsupporting

confidence: 90%

Intermittent heat exposure and thirst in rats

Barney

Kuhrt

2016

Physiol Rep

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Adequate water intake, supporting both cardiovascular function and evaporative cooling, is a critical factor in mitigating the effects of heat waves, which are expected to increase with global warming. However, the regulation of water intake during periods of intermittent heat exposure is not well understood. In this study, the effects of access to water or no access during intermittent heat exposure were assessed using male Sprague‐Dawley rats exposed to 37.5°C for 4 h/day. After 7 days of intermittent heat exposure, reductions in evaporative water loss were observed in all animals and reductions in water intake following heat exposure occurred as the days of heat exposure increased. Rats that were not allowed water during the 7 days of exposure had decreased rehydration levels, however, rats allowed access to water increased water intake during exposure and exhibited higher overall rehydration levels over the same time period. Peripheral administration of angiotensin II, mimicking activation of volemic thirst, or hypertonic saline solution, activating intracellular thirst, did not result in alteration of water intake in rats exposed to heat with access to water compared to control rats. In contrast, rats exposed to heat without access to water had reduced water intake after administration of hypertonic saline and increased water intake after administration of angiotensin II compared to control rats. These experiments demonstrate that thirst responses to intermittent heat exposure are altered by providing water during heat exposure and that intermittent heat exposure without access to water alters drinking responses to both intracellular and extracellular thirst challenges.

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Nycthemeral variation in thermal dehydration-induced thirst

Cited by 5 publications

References 24 publications

Heat acclimation and thirst in rats

Heat acclimation and thirst in rats

Thermal dehydration-induced thirst in spontaneously hypertensive rats

Intermittent heat exposure and thirst in rats

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