NVS and Staphylococci in the Oral Cavity – A Cause of Infective Endocarditis

Ohara‐Nemoto, Yuko; Kimura, Shigenobu; Nemoto, Takayuki

doi:10.5772/29960

Cited by 1 publication

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References 90 publications

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“…The members of genus Staphylococcus are found in normal human microflora of the gastro-intestinal tract, skin and nasal cavity. These microorganisms are isolated from dental plaque and saliva, therefore the oral cavity is considered to be a common habitat for these pathogenic bacteria of infective endocarditis [1]. In addition, S. aureus is a well-defined human pathogenic microorganism which produces many toxins that cause various inflammatory diseases, purulent skin lesion, toxic shock syndrome and food poisoning [2].…”

Section: Introductionmentioning

confidence: 99%

Identification and Protein Fingerprinting of Staphylococcus aureus Species Isolated from Tooth Decay

Çine

Berber

Avşar

2015

Proc. Natl. Acad. Sci., India, Sect. B Biol. Sci.

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Staphylococcus aureus is the most prevalent human pathogenic microorganism worldwide. In the present study, a total of 57 S. aureus strains, including 54 clinical isolates obtained from dental hospitals and three reference strains were characterized by phenotypic characteristics and SDS-PAGE protein profiling. Out of the 132 clinical specimens, 54 S. aureus strains were isolated and identified according to their morphological and physiological characteristics. The strains were tested against 13 standard antibiotics by using disc diffusion procedure. Antibiogram results showed that the highest resistance among the isolates was determined against ampicillin (83.6 %), whereas they were susceptible to sulfamethoxazole/trimethoprim, cefoperazone/sulbactam, vancomycin and imipenem. In addition, multidrug resistance index values of 12 (22.2 %) of the isolates were higher than the reference value of 0.2. The numerical analysis of wholecell protein profiles of S. aureus strains revealed 2 major clusters at similarity levels of 57 % or above. Furthermore, the numerical analysis of extra-cellular protein profiles of S. aureus strains yielded 2 major clusters at similarity levels of 48 % or above. In conclusion, the present findings revealed that use of conventional methods with the numerical analysis of whole-cell and extra-cellular protein profiles might be useful for the more reliable identification of S. aureus strains isolated from tooth decay.

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Section: Introductionmentioning

confidence: 99%