Nutritional Support in Inflammatory Bowel Disease

Heatley, R. V.; Harries, Anthony

doi:10.1159/000171087

Cited by 5 publications

(4 citation statements)

References 25 publications

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“…Others did not confirm this relationship [ 15]. Therefore a fiber-rich diet is considered useful for long time treatment of UC by some authors, who think that the passage of hard stools could provoke bleeding from the inflamed mucosa [1], and unfavorable by others [16]. In the group of patients of our study, the intake of a diet rich in fruit and vegetables significantly reduced the risk of relapse of the disease.…”

Section: Discussioncontrasting

confidence: 51%

Ulcerative Colitis in Remission: Is It Possible to Predict the Risk of Relapse?

Leo¹,

Leandro²,

Matteo

et al. 1989

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A series of anamnestic, clinical, endoscopic and histologic parameters was evaluated in 64 patients with ulcerative colitis in remission to assess whether any of these had predictive value of relapse. All patients with quiescent disease were followed for at least 6 months. The statistical analysis was carried out by means of likelihood χ² test, receiver operating characteristic curve, Youden index and stepwise logistic regression. Eighteen patients out of 64 (28 %) had a relapse, in a mean period of 9 months after the beginning of the study. The findings of our study suggest that only three factors were useful in selecting a subpopulation with a higher risk of recurrence: (a) a fiber-poor diet; (b) a number of previous episodes of relapse higher than 10, and (c) the presence of extraintestinal manifestations.

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Section: Discussioncontrasting

confidence: 51%

Ulcerative Colitis in Remission: Is It Possible to Predict the Risk of Relapse?

Leo¹,

Leandro²,

Matteo

et al. 1989

Digestion

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“…Nicht selten dauert es Jahre ron den ersten Symptomen bis zur Erstdiagnose. Chronisch rezidivierende Diarrh6en, Gewichtsverlust, Schmerzzust~inde, Mangelerscheinungen und allgemeine Abgeschlagenheit k6nnen zu erheblicher Beeintr~ichtigung ira taglichen Leben fª [11]. 10 bis 20% der Patienten mit Morbus Crohn haben einen manifesten Calciummangel [17].…”

Section: Ti C Rath Et Alunclassified

“…Wie bei einer Erh6hung der "yGT muf3 man bei erh6hter alkalischer Phosphatase an cine Erkrankung der Gallenwege denken, wie zum Beispiel cine Pericholangitis oder prim~ sklerosierende Cholangitis. Differentialdiagnostisch kommen bei erh6hter alkalischer Phosphatase noch Knochenerkrankungen wie Osteomalazie in Frage, ein Mangelsymptom, das bis zu 30% der Crohn-Patienten betrifft [11]. Erh/3hte yGT-Werte wie ein Anstieg der Transaminasenaktivit~it ira Serum k/3nnen aber auch auf cine Leberzellsch~idigung im Sinne einer chronischen Hepatitis oder Zirrhose hinweisen.…”

Section: Abbildung 2 Hdufigkeit Erhohter Aktivitgit Und Konzentra~iounclassified

Mangelzustände und Komplikationen bei chronisch entzündlichen Darmerkrankungen

et al. 1998

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Deficiencies and Complications in Inflammatory Bowel DiseaseSummary. Deficiencies of vitamins and trace elements ate frequent in inflammatory bowel disease. Airo of this study was to evaluate retrospectively the prevalence of these deficiencies and of liver complications in a large population. The records from 392 out-patients, 279 with Crohn's disease (160 female, 119 male) and 113 with ulcerative colitis (56 female, 57 male) were analyzed. Deficiencies were found in 85% of patients with Crohn's disease vs. 68% with ulcerative colitis during the course of the disease, predominantIy a deficiency of iron and of calcium. Less frequently deficiencies of zinc, protein, cyanocobalamin, and folic acid were found. Elevated liver enzymes were seen in 38% of patŸ with Crohn's disease vs. 27% with ulcerative colitis. In order of frequency: y-glutamyl-transferase, ALAT, AP, ASAT, and bilirubin. Gallstones were present in t2% of patients with Crohn's disease and 4% with ulcerative colitis. 6% of patients with Crohn's disease and 4% with ulcerative colitis had kidney Klinik und Potiklinik fª Innere Medizia 1. Klinikum der Unive¡ Regensburg.

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“…Betroffen ist etwa jeder tausendste Einwohner der Bundesrepublik Deutschland, wobei die Zahl der Patienten mit Colitis ulcerosa seit l~ingerer Zeit stabil ist, w~ihrend die Zahl der Patienten mit Morbus Crohn bis vor wenigenJahren zugenommen hat [21]. Differentialdiagnostisch kommen bei er-h6hter alkalischer Phosphatase noch Knochenerkrankungen wie Osteomalazie in Frage, ein Mangelsymptom, das bis zu 30% der Crohn-Patienten bet¡ [11]. Dies deckt sich mit unseren Beobachtungen, dafl pathologische Funktionsparameter bei Crohn-Patienten zwar h~iufiger sind, die Serumaktivit?iten der alkalischen Phosphatase bei Patienten mit Colitis ulcerosa aber im Schnitt h6her lagen.…”

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