Nutritional Strategies to Optimize Outcomes among Infants with Congenital Heart Disease

Miller, Audrey N.; Naples, Angelo

doi:10.1542/neo.24-8-e492

Cited by 2 publications

(2 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite the existence of numerous practice guidelines aimed at guiding nutritional care in recent years, this variability persists. The implementation of standardized feeding protocols has been proven to reduce this problem and improve outcomes for CHD patients [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Association between type of congenital heart disease with child growth and development status: A cross-sectional study in Medan, Indonesia

Amelia,

Yosephine,

Tobing

et al. 2023

Narra J

View full text Add to dashboard Cite

Congenital heart disease (CHD) is a congenital disorder primarily affecting newborns and children. Children with CHD have a greater risk of experiencing growth delays or disorders compared to healthy children. CHD also affects various aspects of a child’s development. The aim of this study was to determine the association of CHD types (cyanotic and acyanotic) with the growth and development status of children. A cross-sectional study was conducted among CHD patients at a national reference hospital in Sumatra, H. Adam Malik General Hospital in Medan, Indonesia. The children's growth status was assessed using the WHO growth chart, and the developmental condition was evaluated through the Denver Developmental Screening Test-II. Chi-squared test and Fisher’s exact test were used to assess the association between the type of CHD with growth and development status in children. Using a consecutive sampling method, a total of 53 individuals were included in this study. Almost half of CHD patients (48.1%) were within the age group of 0–2 years and more than half (61.1%) were girls. Acyanotic CHD (74.1%) was more prevalent than cyanotic CHD (25.9%), with ventricular septum defect (VSD) as the most common diagnosis. A total of 37% of children with CHD suffered from malnutrition, whereas the remaining 62.9% had good nutrition. The Denver Developmental Screening Test-II indicated that 81.4% of the children were normal, whereas 18.5% had developmental disorders. Our data suggested a significant association between cyanotic CHD and poor growth status in children based on weight-for-age, weight-for-length, and body mass index (BMI)-for-age. However, there was no association between the type of CHD and developmental status in children. This study highlights that the type of CHD is significantly associated with the growth status of children, but not with their developmental status.

show abstract

Section: Discussionmentioning

confidence: 99%

Association between type of congenital heart disease with child growth and development status: A cross-sectional study in Medan, Indonesia

Amelia,

Yosephine,

Tobing

et al. 2023

Narra J

View full text Add to dashboard Cite

show abstract

“…Feeding intolerance, gastric mucosal hypertrophy, and NEC were reported as associated with feeding newborns with ductal-dependent heart defects preoperatively, while receiving PGE1 treatment [ 23 , 24 ]. However, adequate nutrition is crucial for infants with congenital heart defects, as many infants are considered malnourished at the time of cardiac surgery, more so infants with cyanotic heart defects [ 25 , 26 , 27 ]. Malnutrition in these infants is multifactorial, and is due to both decreased intake, as nutritional practices have great variability between centers, and increased energy expenditure, due to their basic disease [ 28 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

Cumulative Dose of Prostaglandin E1 Determines Gastrointestinal Adverse Effects in Term and Near-Term Neonates Awaiting Cardiac Surgery: A Retrospective Cohort Study

Ofek Shlomai,

Lazarovitz,

Koplewitz

et al. 2023

Children

View full text Add to dashboard Cite

Objective: This study aimed to assess the association between treatment characteristics of prostaglandin E1 including initiation time and duration, maximal and cumulative doses, and adverse effects. Design: A retrospective cohort study in which medical records of neonates with duct-dependent lesions were studied for treatment parameters and adverse effects. Multivariable logistic regression model was applied for testing the effect PGE1 variables on outcomes. Main outcome measures: The primary outcomes of this study were association of adverse effects of PGE1 treatment with maximal dose, cumulative dose, and treatment duration. The secondary outcomes included safety of feeding in infants treated with PGE1. Results: Eighty-two infants with duct-dependent lesions receiving PGE1 were included. Several infants who received early PGE1 treatment required ventilation support. Feeds were ceased more often as the cumulative dose and duration of PGE1 treatment increased. Gastrointestinal adverse effects were significantly associated with the cumulative dose of PGE1 and treatment duration. Apneas, hyperthermia, and tachycardia were associated with maximal dose. Our data did not demonstrate a difference in the incidence of NEC associated with characteristics of PGE1 treatment. Conclusion: Cumulative PGE1 dose is associated with gastrointestinal adverse effects in neonates. Lower doses should be considered in neonates expecting prolonged PGE1 treatment.

show abstract

Nutritional Strategies to Optimize Outcomes among Infants with Congenital Heart Disease

Cited by 2 publications

References 72 publications

Association between type of congenital heart disease with child growth and development status: A cross-sectional study in Medan, Indonesia

Association between type of congenital heart disease with child growth and development status: A cross-sectional study in Medan, Indonesia

Cumulative Dose of Prostaglandin E1 Determines Gastrointestinal Adverse Effects in Term and Near-Term Neonates Awaiting Cardiac Surgery: A Retrospective Cohort Study

Contact Info

Product

Resources

About