Nutritional status variation and intestinal and extra intestinal symptomatology in patients with celiac disease and non-celiac gluten sensitivity given specialized dietary advice

Abstract

Objective: To investigate the nutritional status variation and symptomatology of patients with celiac disease and non-celiac gluten sensitivity after specialized dietary advice Methods: This prospective study included 80 patients with celiac disease and non-celiac gluten sensitivity. Clinical, metabolic, and nutritional variables were collected from medical records, and the symptomatology was investigated by the Metabolic Screening Questionnaire. The variables were assessed on two occasions (T1 - before dietary advice and T2 - after dietary advice) with an interval of three months between T1 and T2 Results: The median age was 42 years. The prevalences of celiac disease and non-celiac gluten sensitivity were 66.2% and 33.8%, respectively. Normal weight prevailed at T1 (58.8%) and T2 (56.3%), but 30.0% of the patients at T1 and 34.9% of the patients at T2 had excess weight. The two conditions had similar symptomatology. The most frequent signs and symptoms on both occasions involved the gastrointestinal tract, followed by energy/activity and emotions. All symptoms decreased significantly after the introduction of a proper diet Conclusion: The patients were normal weight on both study occasions (T1 and T2), and the symptoms improved after dietary advice. Thus, we reinforce the importance of proper dietary management in both clinical conditions to make dietary adjustments that improve these individuals' symptomatology.

Self-Reported Non-Celiac Gluten Sensitivity in Brazil: Translation, Cultural Adaptation, and Validation of Italian Questionnaire

“…Researchers have been attempting to characterize the NCGS rates in different countries [2,8,12,13,14,15,16,17,18]. In Latin America, there are few data about the prevalence or characterization of NCGS [15,19,20,21,22].…”

“…In Brazil, only one study evaluated NCGS [19], in which the authors aimed to differentiate CD and NCGS symptoms in 80 Brazilian patients. However, there is no study evaluating NCGS in the Brazilian population nationwide due to the lack of a valid instrument in Brazilian Portuguese.…”

Optimization of nutrient retention in whole flours extruded from cowpea biofortified grain

“…Transforming Biofortified Whole Cowpea Flour (BWCF) into crunchy expanded extrudates or instant flours is a convenient option to consume this nutritious and healthy grain, especially important for those who have reduced nutrient absorption capacity due to intestinal injuries (Ribeiro et al, 2017;García-Manzanares & Lucendo, 2011) and for those who choose not to eat foods containing gluten, whose alternatives are less nutritious, since the functionality of gluten is usually replaced by that of starch (Horstmann et al, 2017;Rai et al, 2018).…”

Estudios clínicos sobre la enfermedad celíaca (2014-2019): revisión sistemática de la prevalencia de la presentación clínica y enfermedades asociadas por edades

“…Síntomas en personas adultas: Los síntomas que pueden presentarse en personas adultas son: diarrea, fatiga, dolor abdominal, pérdida de peso, distensión abdominal, náuseas, vómitos, dispepsia, epigastralgia, pérdida de apetito, esteatorrea, flatulencia, reflujo, irritabilidad, estreñimiento, anemia ferropénica, dermatitis herpetiforme, aftas orales, alteraciones óseas (osteopenia y osteoporosis), alteraciones psiquiátricas (ansiedad, depresión, tendencia al suicidio), alteraciones neurológicas (cefalea, epilepsia, neuropatía periférica, ataxia) y alteraciones ginecológicas (amenorrea, abortos recurrentes, menopausia precoz, infertilidad) [22][23][24]26,28,29,31,32 .…”

“…La depresión, osteoporosis y fibromialgia son más frecuentes en mujeres 23,24 . Alrededor del 30% de los pacientes con EC presentan sobrepeso y el 12,5% obesidad en el momento del diagnóstico 24,25,29 . La desnutrición y el sobrepeso son dos estados muy frecuentes de la celiaquía, por lo que no debemos olvidarlos, sobre todo la obesidad/ sobrepeso que podríamos no asociar a la EC.…”