Water is an indispensable resource for the maintenance of life; however, the available volume for consumption has decreased over a period of life, as a result of which, the availability of water that is inferior in quality has increased. In this context, we aimed to evaluate the growth and yield of okra (Santa Cruz cultivar) under different nitrogen rates and irrigation facilities using post-treated domestic wastewater through sand filter with intermittent flow in a Brazilian semiarid region. The experiment was performed in the Pombal region of the Paraíba state, Brazil using a randomized block design with six nitrogen Rates (N 1 = 0, N 2 = 40, N 3 = 80, N 4 = 120, N 5 = 160, and N 6 = 200 kg ha -1 ) and irrigation by using wastewater. The water was added to the treatment with 100% (160 kg ha -1 ) using nitrogen fertilization recommendation and irrigation water supply. The effects of treatments on the growth and production variables of okra plants were evaluated.