Nutritional Status, Growth and Development in Children Undergoing Intensive Treatment for Cystic Fibrosis

Gaskin, K. J.; Waters, Donna; Baur, Louise A.; Soutter, Velencia; Gruca, Margaret

doi:10.1111/j.1651-2227.1990.tb11610.x

Cited by 19 publications

(7 citation statements)

References 13 publications

(4 reference statements)

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“…Meeting the increased energy requirements in CF is very difficult and many studies demonstrate that energy intakes are often sub‐optimal, and aggressive intervention, such as enteral feeding are required to optimise energy intakes 25 –37 . Higher fat intakes have been linked with greater energy intakes and improved growth and nutritional status 8 , 23 , 38 .…”

Section: Pert Dosage Guidelinesmentioning

confidence: 99%

Pancreatic enzyme replacement therapy in cystic fibrosis: Australian guidelines

Anthony

Collins

Davidson

et al. 1999

J Paediatrics Child Health

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Pancreatic enzyme replacement therapy (PERT) is a major factor associated with achieving optimum growth and nutritional status in cystic fibrosis (CF) patients with pancreatic insufficiency and consequent malabsorption. Currently in Australian CF clinics policies for the usage of PERT vary considerably. This paper highlights the current issues related to fat absorption and use of PERT in CF. It also provides evidence to support the recommendation of a PERT dose based on a standard ratio of lipase units per gram of dietary fat consumed for individual patients. A consistent approach to PERT doses will facilitate identification of patients whose PERT intake increases their risk of fibrosing colonopathy and for whom gastroenterological review is warranted. Recent reports indicate that PERT intake can be reduced with a secondary improvement in growth and nutrition status as a consequence of increased dietetic input. These Australian guidelines for the judicious use of PERT in CF should lead not only to a refinement in nutritional management of patients with CF but should also facilitate an improvement in compliance with therapy due to sophistication in patient education materials. The Australian guidelines for the use of PERT in CF if correctly applied, will also provide patients and their families with a better understanding of the relationship between PERT and nutritional status.

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Section: Pert Dosage Guidelinesmentioning

confidence: 99%

Pancreatic enzyme replacement therapy in cystic fibrosis: Australian guidelines

Anthony

Collins

Davidson

et al. 1999

J Paediatrics Child Health

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“…Poor weight gain is often encountered in patients with cystic fibrosis (Schwachman & Kulczycki, 1958; Sprout & Huang, 1965; Mitchell Heggs et al ., 1976) as it can arise as a consequence of inadequate nutritional intake, malabsorption, and increased energy expenditure (Soutter et al ., 1986; Corey et al ., 1988; Shepherd et al ., 1988; Buchdahl et al ., 1989). Although aggressive nutritional therapy has contributed to improvements in pulmonary function, growth and survival, weight loss may still occur during intercurrent infection (Levy et al ., 1985; Gaskin et al ., 1990; Steinkamp et al ., 1990).…”

mentioning

confidence: 99%

The relationship between insulin, IGF‐I and weight gain in cystic fibrosis

Taylor

Thomson

Bruce-Morgan

et al. 1999

Clinical Endocrinology

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“…Todavia, no grupo (4-16 anos) em que foi introduzida a dieta noturna por gastrostomia foi verificado melhora significante nos indicadores nutricionais, após 18 meses de intervenção 41 . O'Loughin et al somente observaram melhora significante no peso, massa magra e gorda após a intervenção por sonda nasoenteral por 6 meses, em pacientes (7-27 anos) que não obtiveram melhora com a suplementação via oral 42 .…”

Section: Discussionunclassified

Resultado de intervenção nutricional em crianças e adolescentes com fibrose cística

Gaspar¹,

Chiba²,

Gomes³

et al. 2002

J. Pediatr. (Rio J.)

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ResumoObjetivo: poucos estudos têm verificado longitudinalmente a evolução do estado nutricional de pacientes com fibrose cística. O objetivo deste estudo foi acompanhar a evolução do estado nutricional, composição corporal e consumo de energia, macro e micronutrientes ingeridos por crianças e adolescentes, mediante intervenção nutricional, no Ambulatório de Fibrose Cística/Pneumologia Pediátrica, do Departamento de Pediatria da UNIFESP.Métodos: a casuística constituiu-se de 18 pacientes, sendo 13 do sexo masculino e 5 do feminino, faixa etária de 0,3 a 18,4 anos. Realizaram-se 3 avaliações: no momento 1 (M1: pré-intervenção nutricional), no M2, após 6 meses, e no M3, após 12 meses. Foram analisados nos 3 momentos: o escore Z de peso/idade (P/I), peso/ estatura (P/E) e estatura/idade (E/I) e o cálculo do registro alimentar de 3 dias. No M1 e M3, verificou-se a composição corporal (antropometria). A conduta nutricional foi hipercalórica, hiperprotéica e houve adequação de macro e micronutrientes.Resultados: observou-se aumento significante do escore Z de E/I (M1=-1,07; M2=-0,69; M3=-0,50) e de massa magra após a intervenção nutricional, sem melhora no escore Z de P/E e massa gorda. Verificou-se aumento no consumo energético nos M2 (139%) e M3 (132%) em relação ao M1 (106%). Houve considerável aumento no consumo de proteína, cálcio, ferro e vitamina C pelos pacientes. A presença de anemia ocorreu em 44,4% (8/18) dos pacientes.Conclusão: o aumento no escore Z de E/I e massa magra ocorreu devido a adequação no consumo de energia, após a intervenção nutricional. Não houve melhora significante no escore Z de P/E e massa gorda, em função do ganho de estatura e de massa magra.J Pediatr (Rio J) 2002; 78 (2): 161-70: fibrose cística, intervenção nutricional, energia e nutrientes, estado nutricional, composição corporal. AbstractObjective: few studies have verified longitudinally the evolution of the nutritional status of patients with cystic fibrosis. The objective of this study is to follow the evolution of the nutritional status, body composition and energy consumption, macronutrients and micronutrients ingested by children and adolescents by means of nutritional interventions at the Clinic of Cystic Fibrosis/Pediatric Pneumology of the Department of Pediatrics of Universidade Federal de São Paulo.Methods: 18 patients were involved in this study, thirteen males and five females with ages ranging from 0.3 to 18.4 years. We performed three evaluations: evaluation 1 (M1-prenutritional intervention), M2 after 6 months, and M3 after 12 months. In these three instances we verified: the z score for weight/age, weight/height and height/age and the calculation of a 3-day diet record. We verified the body composition (anthropometry) in M1 and M3. The nutritional interventions were hypercaloric, hyperproteic, with adequate amount of ingested macronutrients and micronutrients.Results: we observed an increase in the z score for height/age (M1=-1.07; M2=-0.69; M3=-0.50) and fat-free mass after the nutritional interventions, without i...

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Nutritional Status, Growth and Development in Children Undergoing Intensive Treatment for Cystic Fibrosis

Cited by 19 publications

References 13 publications

Pancreatic enzyme replacement therapy in cystic fibrosis: Australian guidelines

Pancreatic enzyme replacement therapy in cystic fibrosis: Australian guidelines

The relationship between insulin, IGF‐I and weight gain in cystic fibrosis

Resultado de intervenção nutricional em crianças e adolescentes com fibrose cística

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