Nutritional properties and osteogenic activity of simulated digestion components and peptides from Larimichthys crocea

Characterization and preparation of food-derived peptides on improving osteoporosis: A review

“…Integrins belong to the cell adhesion receptor family, which regulates the location and activities of proteases as well as cell adhesion and proliferation ( Hou, Wang, Li, Hao, & Hang, 2021 ). Bioactive peptides, such as osteogenic peptides and integrins, can bind with each other to promote various cell functions, including growth, differentiation, and adhesion ( Lara-Ochoa, Ortega-Lara, & Guerrero-Beltrán, 2021 ; Xu et al, 2022 , Xu et al, 2023 ). As shown in Fig.…”

Editorial: Food-derived polyphenols: functional regulation in chronic diseases

“…Among them, polyphenols show potential antioxidative, anticancer, anti-hypertensive, osteogenic, and anti-inflammatory effects ( 3 ), which are considered functional nutraceuticals in preventing chronic diseases ( Figure 1 ). On the other hand, researches have also revealed that the functional qualities of food-derived components are related to processing, preservation, and digestion procedures ( 4 ). In addition, food-derived polyphenols can be metabolized via different pathways and eventually absorbed in the body to exert their efficacy ( 5 ).…”

Portable and Rapid Fluorescence Turn-On Detection of Total Pepsin in Saliva Based on Strong Electrostatic Interactions

“…Pepsin is present as inactive zymogen in the granulocytes of the main cells of the human stomach lining and is one of the most important digestive enzymes in the human body. − Since the presence of pepsin in the esophagus or more proximal sites indicates reflux, it can be used as a biomarker for the objective assessment of gastroesophageal reflux disease (GERD) . Although the laryngeal mucosa is resistant to acids above pH 4, pepsin poses a threat to human health even under mildly acidic or alkaline conditions. , Relevant studies have shown that the detection of pepsin in saliva can be considered a simple, convenient, and noninvasive method for the diagnosis of the proximal reflux of gastric contents or laryngopharyngeal reflux (LPR). ,, However, current methods for the detection of pepsin in saliva are still limited due to the low concentration, , the complexity of the matrix, and the strong pH-dependent activity .…”