Nutritional profile and pharmacological aspect of Houttuynia cordata Thunb. and their therapeutic applications

Pradhan, Srimay; Rituparna, Swati; Dehury, Haripriya; Dhall, Monalisa; Singh, Yengkhom Disco

doi:10.1016/j.prmcm.2023.100311

Cited by 4 publications

(1 citation statement)

References 124 publications

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“…The aqueous HC extract emerges as a source of natural antioxidants, promoting health benefits, and is widely consumed as a beverage in China. Pradhan et al observed that limonene, bornyl acetate, and methylnonyl ketone within the HC extract exhibited antibacterial effects against Gram-positive bacteria [45]. Although results from antioxidant assays indicate that the as-prepared Houttuynia cordata leaf extract possesses substantial antioxidant activity, this plant extract has shown negligible antibacterial activity toward all the tested bacterial strains based on antimicrobial susceptibility testing [46].…”

Section: Discussionmentioning

confidence: 99%

Evaluating Antioxidant Performance, Biosafety, and Antimicrobial Efficacy of Houttuynia cordata Extract and Microwave-Assisted Synthesis of Biogenic Silver Nano-Antibiotics

Moorthy,

Chang,

Huang

et al. 2023

Antioxidants

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From the traditional Chinese medicine point of view, although Houttuynia cordata extract (HCE) possesses an incredible amount of phytonutrients and exhibits antioxidant activities, excessive doses of HCE can cause danger to organisms and lead to death. In this study, we first examine HCE’s overall phenolic and flavonoid content, antioxidant efficacy, and antibacterial activity. Results show that HCE is suitable as a bio-reducing agent for the microwave-assisted synthesis of silver nanoparticles (HCE-AgNPs) with enhanced antioxidant and antimicrobial performance. Under an optimized microwave condition (i.e., 100 °C for 10 min), the HCE-stabilized AgNPs were confirmed with a UV-visible peak at 430 nm and 19.7 ± 4.2 nm in size. Physicochemical properties of HCE-AgNPs were extensively characterized by zeta-potential, FT-IR, XRD, and XPS measurements. Compared to the HC extract counterpart, HCE-AgNPs display superior antioxidant activity, higher DPPH scavenging efficiency, and enhanced broad-spectrum bactericidal activity to inhibit the growth of all tested bacterial strains at doses of 2 μg/mL. Biosafety evaluation indicated that HCE-AgNPs are noncytotoxic on human red blood cells. These data show that the microwave synthesis of AgNPs exhibits a great antioxidant ability, superior antibacterial activity, and a trivial hemolytic effect, providing another bactericidal therapy strategy to address the increasing healthcare-associated infections.

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Section: Discussionmentioning

confidence: 99%

Evaluating Antioxidant Performance, Biosafety, and Antimicrobial Efficacy of Houttuynia cordata Extract and Microwave-Assisted Synthesis of Biogenic Silver Nano-Antibiotics

Moorthy,

Chang,

Huang

et al. 2023

Antioxidants

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Nutritional, anti-nutritional and morphological characterization of wild edible species of Solanum found in North East India

Ningthoujam,

Deo,

Phurailatpam

et al. 2023

Genet Resour Crop Evol

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The outcome of this study shows that S. species are considerably variate in nutritional, anti-nutritional and morphological characters. Maximum plant height (161.16±5.67 cm) and number of owers per in orescence (12.49±1.55) was obtained from S. torvum while S. nigrumattained minimum fruit length (6.08±0.43 mm) and girth (6.48±0.55 mm). Among all the berries, S. macrocarpon has wider girth than length. So, it perceived maximal fruit girth (73.65±0.65 mm) and lowest number of owers per in orescence (2.04±0.43). Being a short period plant, S. nigrum also recorded least number of days to rst owering (19.94±3.63) and no. of days taken for fruit development (31.27±2.99). Regarding nutritional composition, highest amount of total carbohydrates (47.44±1.75 mg/g) and starch (8.76±0.16 mg/g) was recorded in S. macrocarpon whereas it has least value of cellulose (0.75±0.007 mg/g). S. ferox achieved maximal amount of total sugar (7.33±0.78 mg/g) and reducing sugar (3.86±0.40 mg/g). Likewise, S. spirale recorded minimum amount of total sugar (2.37±0.12 mg/g) and reducing sugar (0.23±0.03 mg/g) while S. torvum obtained highest quantity of cellulose (2.04±0.08 mg/g). Total soluble protein was observed from S. villosum with an amount of 1.54±0.03 mg/g whereas S. gilo (white) obtained lowest 0.74±0.03 mg/g soluble protein. As for anti-nutritional highest quantity of phytic acid was recorded in S. spirale (5.34 ±0.18 mg/g) while least amount was obtained from S. ferox(0.72 ±0.01 mg/g). However, maximal amount of cyanogen i.e., 54.24 ±0.59 µg/g was attained from S. violaceum(spineless) and lowest quantity of cyanogen at 12.72 ±0.56 µg/g was recorded in S. gilo (green).

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Identification of phytoconstituents from Houttuynia cordata Thunb. as dipeptidyl peptidase-IV and sodium glucose cotransporter 2 inhibitors guided by molecular docking

Pakyntein,

Thabah,

Rai

et al. 2024

Phytomedicine Plus

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Nutritional profile and pharmacological aspect of Houttuynia cordata Thunb. and their therapeutic applications

Cited by 4 publications

References 124 publications

Evaluating Antioxidant Performance, Biosafety, and Antimicrobial Efficacy of Houttuynia cordata Extract and Microwave-Assisted Synthesis of Biogenic Silver Nano-Antibiotics

Evaluating Antioxidant Performance, Biosafety, and Antimicrobial Efficacy of Houttuynia cordata Extract and Microwave-Assisted Synthesis of Biogenic Silver Nano-Antibiotics

Nutritional, anti-nutritional and morphological characterization of wild edible species of Solanum found in North East India

Identification of phytoconstituents from Houttuynia cordata Thunb. as dipeptidyl peptidase-IV and sodium glucose cotransporter 2 inhibitors guided by molecular docking

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