Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer’s disease: A focus on human studies

Pistollato, Francesca; Iglesias, Rubén Calderón; Ruíz, R.; Aparicio, Silvia; Crespo, Jorge; López, Luís Alonso Dzul; Manna, Piera Pia; Giampieri, Francesca; Battino, Maurizio

doi:10.1016/j.phrs.2018.03.012

Cited by 172 publications

(110 citation statements)

References 209 publications

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“…The diet pattern plays an essential role in the composition of gut microflora and affects psychiatric conditions such as depression and anxiety [75,76]. Diets rich in fruits, whole grains, vegetables, and fish have been proved to be beneficial to brain function such as the lower risk of dementia by reducing gut inflammation and neurodegeneration [77]. By far, several well-known "Mediterranean-like" dietary patterns have shown neuroprotective effects, i.e., Mediterranean diet (MeDi), Dietary Approach to Stop Hypertension (DASH) diet, and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet [77,78].…”

Section: Food and Food-derived Metabolitesmentioning

confidence: 99%

“…Diets rich in fruits, whole grains, vegetables, and fish have been proved to be beneficial to brain function such as the lower risk of dementia by reducing gut inflammation and neurodegeneration [77]. By far, several well-known "Mediterranean-like" dietary patterns have shown neuroprotective effects, i.e., Mediterranean diet (MeDi), Dietary Approach to Stop Hypertension (DASH) diet, and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet [77,78]. Patients with Alzheimer's disease (AD) and atherosclerosis benefit from these "Mediterranean-like" diets [79].…”

Section: Food and Food-derived Metabolitesmentioning

confidence: 99%

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The progress of gut microbiome research related to brain disorders

Zhu

Jiang

et al. 2020

J Neuroinflammation

277

202

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There is increasing evidence showing that the dynamic changes in the gut microbiota can alter brain physiology and behavior. Cognition was originally thought to be regulated only by the central nervous system. However, it is now becoming clear that many non-nervous system factors, including the gut-resident bacteria of the gastrointestinal tract, regulate and influence cognitive dysfunction as well as the process of neurodegeneration and cerebrovascular diseases. Extrinsic and intrinsic factors including dietary habits can regulate the composition of the microbiota. Microbes release metabolites and microbiota-derived molecules to further trigger host-derived cytokines and inflammation in the central nervous system, which contribute greatly to the pathogenesis of host brain disorders such as pain, depression, anxiety, autism, Alzheimer's diseases, Parkinson's disease, and stroke. Change of blood-brain barrier permeability, brain vascular physiology, and brain structure are among the most critical causes of the development of downstream neurological dysfunction. In this review, we will discuss the following parts: Overview of technical approaches used in gut microbiome studies Microbiota and immunity Gut microbiota and metabolites Microbiota-induced blood-brain barrier dysfunction Neuropsychiatric diseases ■ Stress and depression ■ Pain and migraine ■ Autism spectrum disorders Neurodegenerative diseases ■ Parkinson's disease ■ Alzheimer's disease ■ Amyotrophic lateral sclerosis ■ Multiple sclerosis

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Section: Food and Food-derived Metabolitesmentioning

confidence: 99%

Section: Food and Food-derived Metabolitesmentioning

confidence: 99%

The progress of gut microbiome research related to brain disorders

Zhu

Jiang

et al. 2020

J Neuroinflammation

277

202

View full text Add to dashboard Cite

show abstract

“…Older adults who maintain a high-quality diet with adequate protein intake have reduced health abnormalities related to muscle and fat mass [6]. The Dietary Approaches to Stop Hypertension (DASH) dietary pattern is a high-quality therapeutic diet known to improve health status in various diverse and at-risk populations resulting in improved heart health, maintained cognitive function, and reductions in metabolic diseases such as diabetes, metabolic syndrome, and nonalcoholic fatty liver disease [8][9][10][11][12]. The primary protein recommendations of the DASH diet are poultry and fish, and it is recommended to decrease red meats from the diet.…”

Section: Introductionmentioning

confidence: 99%

A Calorie-Restricted DASH Diet Reduces Body Fat and Maintains Muscle Strength in Obese Older Adults

et al. 2019

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This study examined the effect of the Dietary Approaches to Stop Hypertension (DASH) diet containing lean red meat on measures of body composition and muscle strength in a cohort of obese adults 65 and older; 36 males (n = 15) and females (n = 21) consumed 1800 kcal/day for 12 weeks under controlled feeding conditions. The study diet included daily intakes of 126 g of meat. Measures of body composition and muscle strength were obtained at weeks 0, 3, 6, 9, and 12. Breakfast, lunch, and dinner were provided every day for 12 weeks, and equal portions of meat were distributed at each meal. Significant effects of the study diet were detected across time for total body weight, body mass index (BMI), waist circumference, hip circumference, body fat percentage, absolute fat mass (AFM), and blood pressure such that a decrease (p < 0.001) was observed over 12 weeks. Significant effects of the study diet were detected across time for sit/stand (p < 0.001) such that an increase was observed. From baseline to study end, total body weight decreased by 6.3% (p < 0.001), body fat percentage decreased by 2.5% (p < 0.001), and absolute fat mass (AFM) decreased by 4.4 kg (p < 0.001). By the study end, skeletal muscle mass (SMM) was positively correlated with handgrip strength (R2 = 0.75; p = 0.001) and resting energy expenditure (REE) (R2 = 0.29; p = 0.001). Handgrip strength, gait, balance, and resting energy expenditure (REE) were well maintained (p > 0.05) throughout the study. These findings suggest that the DASH diet has the potential to be a tool to preserve muscle strength while reducing fat mass in obese older adults.

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“…Based on our understanding of nutritional requirements and their likely health impacts as described above, healthy dietary patterns can be generally described as those that are rich in healthpromoting foods, including plant-based foods, fresh fruits and vegetables, antioxidants, soya, nuts, and sources of omega-3 fatty acids, and low in saturated fats and trans fats, animal-derived proteins, and added/refined sugars [48]. Patterns such as these are naturally occurring in certain regions of the world and rooted in local/regional tradition and food sources, as is the case for the traditional Mediterranean and Asian diets.…”

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confidence: 99%

Defining a Healthy Diet: Evidence for the Role of Contemporary Dietary Patterns in Health and Disease

2020

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The definition of what constitutes a healthy diet is continually shifting to reflect the evolving understanding of the roles that different foods, essential nutrients, and other food components play in health and disease. A large and growing body of evidence supports that intake of certain types of nutrients, specific food groups, or overarching dietary patterns positively influences health and promotes the prevention of common non-communicable diseases (NCDs). Greater consumption of health-promoting foods and limited intake of unhealthier options are intrinsic to the eating habits of certain regional diets such as the Mediterranean diet or have been constructed as part of dietary patterns designed to reduce disease risk, such as the Dietary Approaches to Stop Hypertension (DASH) or Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diets. In comparison with a more traditional Western diet, these healthier alternatives are higher in plant-based foods, including fresh fruits and vegetables, whole grains, legumes, seeds, and nuts and lower in animal-based foods, particularly fatty and processed meats. To better understand the current concept of a “healthy diet,” this review describes the features and supporting clinical and epidemiologic data for diets that have been shown to prevent disease and/or positively influence health. In total, evidence from epidemiological studies and clinical trials indicates that these types of dietary patterns reduce risks of NCDs including cardiovascular disease and cancer.

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Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer’s disease: A focus on human studies

Cited by 172 publications

References 209 publications

The progress of gut microbiome research related to brain disorders

The progress of gut microbiome research related to brain disorders

A Calorie-Restricted DASH Diet Reduces Body Fat and Maintains Muscle Strength in Obese Older Adults

Defining a Healthy Diet: Evidence for the Role of Contemporary Dietary Patterns in Health and Disease

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