Nutritional Muscular Dystrophy in Calves. II. Addition of Selenium and Tocopherol to a Basal, Dystrophogenic Diet Containing Cod-Liver oil

Maplesden, D. C.; Loosli, J. K.

doi:10.3168/jds.s0022-0302(60)90215-0

Cited by 19 publications

(5 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These findings were established in experiments with chicks, but may well be valid for non-avian species too. Previous reports that MD induced by unsaturated fats in lambs (Welch et al 1960), calves (Maplesden & Loosli 1960), rabbits (Draper 1957) and pigs (Grant) cannot be prevented by selenium administration are in good agreement with the findings in the present experiments. In the investigation of Tanhuanpiiii upon the influence of dietary methyl linolate on experimental MD, the correlation between the amounts of dietary tocopherol and dietary unsaturated fats was clearly demonstrated, but a possible effect of selenium in this connection was not studied.…”

Section: Muscle Degenerationsupporting

confidence: 93%

The Vitamin E-Deficiency Syndrome in Pigs

Nafstad¹,

Tollersrud²

1970

Acta Vet Scand

View full text Add to dashboard Cite

Section: Muscle Degenerationsupporting

confidence: 93%

The Vitamin E-Deficiency Syndrome in Pigs

Nafstad¹,

Tollersrud²

1970

Acta Vet Scand

View full text Add to dashboard Cite

“…Between these two extremes lie the degenerative diseases of muscle in chicks and cattle, and probably other conditions, against which only one of the two nutrients is an effective protective agent, the other being partially so. Thus Dam & Smdergaard (1957) Maplesden & Loosli, 1960). It seems that the naturally occurring dystrophies in both lambs and calves may be primarily Se deficiency, whereas the dystrophies induced in these animals by cod-liver oil are mainly vitamin E deficiency (in this connexion, see also Welch, Hoekstra, Pope & Phillips, 1960).…”

Section: Discussionmentioning

confidence: 99%

The effect of tocopherol, vitamin A, selenium and anti-oxidants on ubiquinone in the rat

Diplock¹,

Edwin²,

Bunyan³

et al. 1961

Br J Nutr

View full text Add to dashboard Cite

“…However, advancements in developing definitive requirements were slow, mostly because of inadequate knowledge regarding proper response variables. During this period, the value of dietary Se to dairy cattle was demonstrated (Maplesden and Loosli, 1960). Selenium would become one of the most, if not the most, researched trace mineral for dairy cattle, and that research would lead to a major change in the way we evaluated trace mineral adequacy (discussed later).…”

Section: -1971mentioning

confidence: 99%

A 100-Year Review: From ascorbic acid to zinc—Mineral and vitamin nutrition of dairy cows

Weiss

2017

Journal of Dairy Science

View full text Add to dashboard Cite

Mineral and vitamin nutrition of dairy cows was studied before the first volume of the Journal of Dairy Science was published and is still actively researched today. The initial studies on mineral nutrition of dairy cows were simple balance experiments (although the methods available at the time for measuring minerals were anything but simple). Output of Ca and P in feces, urine, and milk was subtracted from intake of Ca and P, and if values were negative it was often assumed that cows were lacking in the particular mineral. As analytical methods improved, more minerals were found to be required by dairy cows, and blood and tissue concentrations became primary response variables. Those measures often were poorly related to cow health, leading to the use of disease prevalence and immune function as a measure of mineral adequacy. As data were generated, mineral requirements became more accurate and included more sources of variation. In addition to milk yield and body weight inputs, bioavailability coefficients of minerals from different sources are used to formulate diets that can meet the needs of the cow without excessive excretion of minerals in manure, which negatively affects the environment. Milk, or more accurately the lack of milk in human diets, was central to the discovery of vitamins, but research into vitamin nutrition of cows developed slowly. For many decades bioassays were the only available method for measuring vitamin concentrations, which greatly limited research. The history of vitamin nutrition mirrors that of mineral nutrition. Among the first experiments conducted on vitamin nutrition of cows were those examining the factors affecting vitamin concentrations of milk. This was followed by determining the amount of vitamins needed to prevent deficiency diseases, which evolved into research to determine the amount of vitamins required to promote overall good health. The majority of research was conducted on vitamins A, D, and E because these vitamins have a dietary requirement, and clinical and marginal deficiencies became common as diets for cows changed from pasture and full exposure to the sun to stored forage and limited sun exposure. As researchers learned new functions of fat-soluble vitamins, requirements generally increased over time. Diets generally contain substantial amounts of B vitamins, and rumen bacteria can synthesize large quantities of many B vitamins; hence, research on water-soluble vitamins lagged behind. We now know that supplementation of specific water-soluble vitamins can enhance cow health and increase milk production in certain situations. Additional research is needed to define specific requirements for many water-soluble vitamins. Both mineral and vitamin research is hampered by the lack of sensitive biomarkers of status, but advanced molecular techniques may provide measures that respond to altered supply of minerals and vitamins and that are related to health or productive responses of the cow. The overall importance of proper mineral and vitamin nutrition is known,...

show abstract

Nutritional Muscular Dystrophy in Calves. II. Addition of Selenium and Tocopherol to a Basal, Dystrophogenic Diet Containing Cod-Liver oil

Cited by 19 publications

References 22 publications

The Vitamin E-Deficiency Syndrome in Pigs

The Vitamin E-Deficiency Syndrome in Pigs

The effect of tocopherol, vitamin A, selenium and anti-oxidants on ubiquinone in the rat

A 100-Year Review: From ascorbic acid to zinc—Mineral and vitamin nutrition of dairy cows

Contact Info

Product

Resources

About