Nutritional Management of Liver Disease

Michel, Kathryn E.

doi:10.1016/s0195-5616(95)50038-5

Cited by 6 publications

(1 citation statement)

References 32 publications

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“…ALP may be raised up to three times in normal dogs under six months old due to increased production of the bone isoenzyme (Willard and Twedt 1994), so an increase in ALP, unless very marked, is of doubtful significance in animals presenting younger than six months. Most dogs in this study were managed with antibiotics, lactulose and a low protein diet to ameliorate encephalopathy, as described by Michel (1995), Taboada and Dimski (1995) and Watson (1996). It is important to avoid reducing dietary protein excessively as protein malnutrition may contribute to hepatic degeneration and increase the need to break down body protein.…”

Section: Prognostic Indicatorsmentioning

confidence: 99%

Medical management of congenital portosystemic shunts in 27 dogs—a retrospective study

Watson

Herrtage

1998

J of Small Animal Practice

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Case records of 27 dogs with medically managed congenital portosystemic shunts were reviewed. Fourteen were followed up by telephone questionnaires to the owners. Age, breed, sex, clinical signs and blood results were similar to previous studies. Weight and quality of life were stable or improved on treatment in all cases. Total serum protein concentration and alanine aminotransferase and alkaline phosphatase activities fell significantly during treatment. Fourteen dogs were euthanased, four were lost to follow-up and nine remained alive. Mean survival time for the dogs euthanased was 9.9 months. Mean follow-up period for the dogs still alive was 56.9 months and all had survived more than 36 months from diagnosis. Surviving dogs with intrahepatic shunts had a significantly shorter follow-up period than dogs with extrahepatic shunts. Two prognostic indicators were identified, age at initial signs and blood urea concentration on presentation, both correlating with survival time. It was demonstrated that a significant proportion of dogs with portosystemic shunts managed medically have a good prognosis.

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Section: Prognostic Indicatorsmentioning

confidence: 99%