Nutritional Intake and Status in Children With Cystic Fibrosis: Does Age Matter?

White, Helen; Wolfe, Susan; Foy, Jeanette; Morton, Alison; Conway, S.P.; Brownlee, Keith B

doi:10.1097/01.mpg.0000237929.45846.78

Cited by 17 publications

(11 citation statements)

References 24 publications

(39 reference statements)

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“…Some results do not show significant association between the nutritional status 28,29 and food intake 9,28,30 in the presence of delta F508 mutation, which indicates that irrespective of the large existing variability, which is due to the genotype, environmental factors may also have influence (including beneficial and harmful effects of the treatment).…”

Section: Discussionmentioning

confidence: 98%

Nutrional status and dietary factors in cystic fibrosis patients with delta F508 mutation

Santos

Steemburgo

2015

Rev. Nutr.

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Objective To examine the association between nutritional status and dietary factors in children and adolescents with cystic fibrosis that are carriers of delta F508 mutation. Methods Cross-sectional study of cystic fibrosis children and adolescents. Nutritional status (body mass index percentile) and dietary intake (3-day diet records presented as a percentage of estimated energy requirement) were assessed. Results Thirty six patients (median of 8.6; interquartile range 6.8-12.5 years; 50% male). The Poisson regression analysis showed that the carriers for delta F508 mutation had 60% lower prevalence ratio of body mass index ≥25° (PR=0.4; 95%IC=0.2-0.8) and 90% lower prevalence ratio (PR=0.1; confidence interval 95%IC=0.02-0.3) of ≥150% of estimated energy requirement when compared with non-delta F508 mutation carriers. The model was adjusted for lung function, estimated energy requirement, and body mass index. Conclusion Carriers for delta F508 mutation showed lower body mass index percentile and lower daily caloric consumption when compared with patients without this mutation.

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Section: Discussionmentioning

confidence: 98%

Nutrional status and dietary factors in cystic fibrosis patients with delta F508 mutation

Santos

Steemburgo

2015

Rev. Nutr.

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“…Previous studies investigating dietary intake in CF children [13][14][15][16] have shown that few achieve the recommended high fat intake (35-40%). For example, Kawchak et al [16] found a three year mean total fat intake 33% of total energy intake in a North American population.…”

Section: Discussionmentioning

confidence: 99%

A fat lot of good: Balance and trends in fat intake in children with cystic fibrosis

Smith

Winn

Seddon

et al. 2012

Journal of Cystic Fibrosis

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Macronutrient intakes did not change significantly in our population of CF children, but there was a consistent imbalance of fat-sources with over-dependence on saturated fats which, in the context of increased survival in CF may potentially increase risk of cardiovascular disease. Further studies are needed to confirm our findings, investigate consequences of fat imbalance and guide clearer advice regarding appropriate proportions of sources of fat for CF patients.

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“…La estimación de las necesidades de energía mediante fórmulas matemáticas específicas no ha sido suficientemente evaluada en la clínica 18 aunque la fórmu-la propuesta en el consenso de 1992 7 se utiliza con frecuencia en el ámbito clínico (figura 3). Siempre debe considerarse cada paciente individualmente, teniendo presente que aunque los niños con FQ alcancen ingestas elevadas de alimentos, muchas veces no logran las metas propuestas 19 . Por ello, es conveniente asegurar una ingesta suficiente, a la vez que evitar también el aporte excesivo, con el consiguiente sobrepeso y siempre considerar el grado de actividad física que el paciente realiza.…”

Section: Déficits Nutricionalesunclassified

Manejo Nutricional en Niños y Adolescentes con Fibrosis Quística

2009

Rev. chil. pediatr.

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Nutritional Management of Children with Cystic Fibrosis: Review and Practical ApplicationsThe importance of optimal nutrition has been well demonstrated in Cystic Fibrosis patients; it affects their mortality, diminishes morbidity and could decrease the deterioration of pulmonary function. However, success of nutritional treatment depends mostly of its early onset. Assistance by enteral route as well as gastrostomy in early stages becomes important since early detection of nutritional deficits and active support result in better response to treatment and slower deterioration of pulmonary function. With an increased survival, new nutritional challenges appear, like deficits of specific EFA, micronutrients, minerals, and possible antioxidant and anti-inflammatory effects of various nutrients. The object of this article is to update nutritional treatment of children and adolescent CF patients. RESUMENLa importancia de un óptimo estado nutricional ha sido bien demostrada en los pacientes con Fibrosis Quística; incide en la mortalidad, disminuye la morbilidad y podría favorecer un menor deterioro de la función pulmonar. Sin embargo, el éxito del tratamiento nutricional depende en gran medida de la prontitud con que se realice, ya que la detección precoz del déficit nutricional favorece una mejor respuesta al tratamiento, a la vez que una actitud más activa favorece un menor deterioro, de manera que tanto el apoyo por vía enteral como la indicación de gastrostomía en etapas menos tardías cobran mayor relevancia. Con el aumento de la sobrevida se presentan además nuevos desafíos nutricionales, como son déficits específicos de AGE, micronutrientes y minerales, al igual que efectos antioxidantes y antiinflamatorios de diversos nutrientes. En esta revisión se espera haber entregado un conocimiento actualizado y aportado algunas herramientas para el manejo nutricional de los niños con FQ.

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Nutritional Intake and Status in Children With Cystic Fibrosis: Does Age Matter?

Cited by 17 publications

References 24 publications

Nutrional status and dietary factors in cystic fibrosis patients with delta F508 mutation

Nutrional status and dietary factors in cystic fibrosis patients with delta F508 mutation

A fat lot of good: Balance and trends in fat intake in children with cystic fibrosis

Manejo Nutricional en Niños y Adolescentes con Fibrosis Quística

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