Nutritional indices in cirrhotic patients

Piquet, Marie-Astrid; Ollivier, Isabelle; Gloro, Romain; Castel, Hélène; Tiengou, Laurent-Eric; Dao, Thông

doi:10.1016/j.nut.2005.06.004

Cited by 19 publications

(8 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Álvares-da-Silva et al (6) observe that the method presents the capacity to detect 100% of the malnutrition cases and, according to Norman et al (31) , identifies the nutritional risk before the serious state of malnutrition. In the evaluation of cirrhotic patients hospitalized, HGS presents the best relation with the nutritional state progress of the cirrhotic patient, as in the study, 89% of the malnourished patients were classified as Child-Pugh B and C (34) . This study demonstrated that HGS does not present statistically significant relation with the Child-Pugh classification, described here as a parameter for the clinical condition of the patient with chronic hepatic disease.…”

Section: Discussionmentioning

confidence: 83%

Nutritional assessment in patients with cirrhosis

Fernandes

Bassani

Nunes

et al. 2012

Arq. Gastroenterol.

View full text Add to dashboard Cite

-Context -Malnutrition in cirrhotic patients with end-stage disease is common, and the degree of nutritional debilitation can play an important role in the pathogenesis of complications and cause a negative impact on prognosis. However, it involves difficulties and controversies regarding the identification of the best nutritional assessment method. Objective -To identify a method that provides a safe and effective nutritional diagnosis. Methods -Cross-sectional study with 129 cirrhotic patients. Anthropometric measurements, subjective global assessment, hand grip strength and bioelectrical impedance. Results -Through phase angle of bioelectrical impedance analysis (BIA) method, significant associations with Child-Pugh (P = 0.008), age group and gender were observed. The ROC (receiver operator characteristic) curve was generated to determine the best cutoff point of the phase angle of cirrhotic patients, serving as one of the reference parameters for the nutritional assessment with bioimpedance in this study, considering the classification through Child-Pugh score as the reference standard for the clinical conditions of patients with cirrhosis. Conclusions -The assessment through bioelectrical impedance presented a statistically significant correlation with Child-Pugh score. The identification of phase angle of 5.44º is the new parameter suggested for the classification of the nutritional conditions of cirrhotic patients.

show abstract

Section: Discussionmentioning

confidence: 83%

Nutritional assessment in patients with cirrhosis

Fernandes

Bassani

Nunes

et al. 2012

Arq. Gastroenterol.

View full text Add to dashboard Cite

show abstract

“…Regarding the protein metabolism assessment, some authors report negative correlation between the albumin levels and CTP score, morbidity and mortality rates (23,29) , while others show that patients classified as CTP-A presented albumin levels within the reference normality rate (23) . Increase in uric acid serum levels in patients with higher TNM classification (Classification of Malignant Tumours (37) has been observed, in addition to positive correlation with mortality in liver cirrhosis patients (1,22) .…”

Section: Discussionmentioning

confidence: 99%

Biochemical Nutritional Profile of Liver Cirrhosis Patients With Hepatocellular Carcinoma

Port

Oliveira

Soldera

et al. 2014

Arq. Gastroenterol.

View full text Add to dashboard Cite

-Context -Liver cirrhosis patients with hepatocellular carcinoma present nutritional alterations and metabolic disorders that negatively impact the prognosis. Objective -The objective is to identify alterations in the metabolism of macro and micronutrients among liver cirrhosis patients with and without hepatocellular carcinoma and their relation to the Child-Turcote-Pugh score and Barcelona Clinic Liver Cancer staging. Methods -Analytical transversal study, with 31 hepatocellular carcinoma patients and 48 liver cirrhosis patients. Laboratorial exams were carried out. The existence of an association between the biochemical parameters and the disease severity as well as the presence of hepatocellular carcinoma was assessed. Results -The metabolic-nutritional profile of liver cirrhosis patients caused by the hepatitis C virus and hepatocellular carcinoma showed alterations, specifically the lipid (total cholesterol, HDL and triglycerides), protein (albumin, creatinine and uric acid), iron (transferrin, iron and ferritin saturation), hematocrit and hemoglobin, zinc and B12 vitamin profiles. There is a relation between nutritional biochemical markers and the Child-Turcote-Pugh, as well as Barcelona Clinic Liver Cancer staging. Conclusion -Considering the existence of alterations in the metabolism of nutrients in liver cirrhosis patients with and without hepatocellular carcinoma, and also that conventional nutritional assessment methods present limitations for this population, the biochemical laboratorial exams are valid to complement the diagnosis of the nutritional state in a quick and practical manner.

show abstract

“…Some authors use albumin as a nutritional index (34, 35), but Piquet et al. (36) found that the decrease in albumin in patients with cirrhosis is related to liver function and not to nutritional indices. In this study, low values of plasma albumin were associated with the severity of disease by Child‐Pugh criteria, a result also found in the work of Roongpisuthipong et al.…”

Section: Discussionmentioning

confidence: 99%

“…The use of biochemical tests for nutritional assessment in individuals with liver disease is questioned, because it may represent liver dysfunction and does not necessarily represent changes in nutritional status. Some authors use albumin as a nutritional index (34,35), but Piquet et al (36) found that the decrease in albumin in patients with cirrhosis is related to liver function and not to nutritional indices. In this study, low values of plasma albumin were associated with the severity of disease by Child-Pugh criteria, a result also found in the work of Roongpisuthipong et al (34), which showed 100.0% of malnutrition in patients with Child-Pugh C. That, surely, is because of the fact that albumin is one of the variables included in the Child-Pugh score.…”

Section: Discussionmentioning

confidence: 99%

Assessment of nutritional status of patients waiting for liver transplantation

Ferreira

Anastácio

Lima

et al. 2011

Clinical Transplantation

View full text Add to dashboard Cite

Patients with advanced liver disease have several risk factors to develop nutritional deficiencies. Accurate nutritional assessment is a real challenge because many of the traditionally measured parameters of nutritional status vary with severity of liver disease independently of nutritional status. The objective of this study was to compare different tools used to assess the nutritional status of patients waiting for a liver transplant. Patients were nutritionally assessed by SGA, anthropometry, handgrip dynamometry and biochemical tests. Clinical variables were cross analyzed with the nutritional assessment methods. There were 159 patients followed. Malnutrition ranged from 6.3% to 80.8% according to the different methods used. Agreement among all the methods was low (K < 0.26). Malnutrition prevalence according to different nutritional assessment tools did not differ among this group of patients in relation to the etiology of liver disease (p > 0.05) but increased with the more advanced stages of disease according to the Child-Pugh score. Only SGA showed significant relationships with clinical variables (Child-Pugh scores, p < 0.05; presence of ascites and/or edema, p < 0.01; and encephalopathy, p < 0.01). The various methods used showed great variability of results, lack agreement among them, and only SGA showed correlation with the progression of liver disease.

show abstract

Nutritional indices in cirrhotic patients

Cited by 19 publications

References 10 publications

Nutritional assessment in patients with cirrhosis

Nutritional assessment in patients with cirrhosis

Biochemical Nutritional Profile of Liver Cirrhosis Patients With Hepatocellular Carcinoma

Assessment of nutritional status of patients waiting for liver transplantation

Contact Info

Product

Resources

About