Nutritional Importance of Carotenoids and Their Effect on Liver Health: A Review

Elvira-Torales, Laura Inés; García‐Alonso, Javier; Periago, M. J.

doi:10.3390/antiox8070229

Cited by 133 publications

(87 citation statements)

References 149 publications

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“…The total carotenoids content was found to be higher in the AH flower (27.29 μg/g) compared with the AL flower (16.96 μg/g). Carotenoids are metabolized in the liver into vitamin A, which helps protect the body from damage caused by oxidative stress and inflammation [ 33 ]. The TPC and TFC content of AL and AH flowers can vary depending on the solvent used for extraction and the origin of the products [ 34 ].…”

Section: Resultsmentioning

confidence: 99%

Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Gupta

Rather

Jha

et al. 2020

Plants

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Artocarpus heterophyllus Lam. (AH) and Artocarpus lakoocha Roxb. (AL) are two endemic plants that grow on the Asian continent. To date, their applications have been aimed at using their fruit as a food source or for some of their therapeutic virtues. In this study, attention was given to the flowers of AH and AL. Initially, the cytotoxicity of the phytoextracts was assessed, and the content of minerals, phenols, and flavonoids was determined. Furthermore, some antioxidant components were identified by HPLC. Furthermore, the ability of AH and AL extracts to modulate the gene expression of some targets involved in the antioxidant response was studied. The results obtained highlighted the nutritional and antioxidant value of the AH and AL flower extracts. This study will contribute to enhancing the use of AH and AL flowers as potential supplements in human nutrition.

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Section: Resultsmentioning

confidence: 99%

Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Gupta

Rather

Jha

et al. 2020

Plants

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“…Dietary carotenoids are absorbed and accumulated in the liver and other organs, where they exert their beneficial effects. The intake of carotenoids can significantly reduce the risk of suffering from liver diseases, such as nonalcoholic fatty liver disease [55]. Moreover, it has been shown that the consumption of wolfberry, which contains high amount of lutein, attenuates retinal mitochondrial stress [56].…”

Section: Discussionmentioning

confidence: 99%

Chlorella sorokiniana Dietary Supplementation Increases Antioxidant Capacities and Reduces ROS Release in Mitochondria of Hyperthyroid Rat Liver

et al. 2020

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The ability of aerobic organisms to cope with the attack of radicals and other reactive oxygen species improves by feeding on foods containing antioxidants. Microalgae contain many molecules showing in vitro antioxidant capacity, and their food consumption can protect cells from oxidative insults. We evaluated the capacity of dietary supplementation with 1% dried Chlorella sorokiniana strain 211/8k, an alga rich in glutathione, α-tocopherol, and carotenoids, to counteract an oxidative attack in vivo. We used the hyperthyroid rat as a model of oxidative stress, in which the increase in metabolic capacities is associated with an increase in the release of mitochondrial reactive oxygen species (ROS) and the susceptibility to oxidative insult. Chlorella sorokiniana supplementation prevents the increases in oxidative stress markers and basal oxygen consumption in hyperthyroid rat livers. It also mitigates the thyroid hormone-induced increase in maximal aerobic capacities, the mitochondrial ROS release, and the susceptibility to oxidative stress. Finally, alga influences the thyroid hormone-induced changes in the factors involved in mitochondrial biogenesis peroxisomal proliferator-activated receptor-γ coactivator (PGC1-1) and nuclear respiratory factor 2 (NRF-2). Our results suggest that Chlorella sorokiniana dietary supplementation has beneficial effects in counteracting oxidative stress and that it works primarily by preserving mitochondrial function. Thus, it can be useful in preventing dysfunctions in which mitochondrial oxidative damage and ROS production play a putative role.

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“…From the visual perspective, the quality of the fruit is directly related to the amount of carotenoids, mainly lycopene and β-carotene, that accumulate in ripe tomato fruits [59]. In addition, the consumption of carotenoids has beneficial effects on human health, since this can reduce the risk of certain forms of cancer, cardiovascular diseases, macular degeneration, among others [60]. In tomato fruits, ripening involves various morphological, physiological, biochemical, and molecular changes, including the degradation of chlorophyll as well as the synthesis and storage of carotenoids (mainly lycopene) during the transition from the chloroplast to the chromoplast [61].…”

Section: Discussionmentioning

confidence: 99%

Impact of Silicon Nanoparticles on the Antioxidant Compounds of Tomato Fruits Stressed by Arsenic

González-Moscoso

Martínez-Villegas

Cadenas‐Pliego³

et al. 2019

Foods

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Tomato fruit is rich in antioxidant compounds such as lycopene and β-carotene. The beneficial effects of the bioactive compounds of tomato fruit have been documented as anticancer activities. The objective of this research was to determine whether arsenic (As) causes changes in the content of antioxidant compounds in tomato fruits and whether Silicon nanoparticles (SiO2 NPs) positively influence them. The effects on fruit quality and non-enzymatic antioxidant compounds were determined. The results showed that As decreased the oxide-reduction potential (ORP), while lycopene and β-carotene were increased by exposure to As at a low dose (0.2 mg L−1), and proteins and vitamin C decreased due to high doses of As in the interaction with SiO2 NPs. A dose of 250 mg L−1 of SiO2 NPs increased glutathione and hydrogen peroxide (H2O2), and phenols decreased with low doses of As and when they interacted with the NPs. As for the flavonoids, they increased with exposure to As and SiO2 NPs. The total antioxidant capacity, determined by the ABTS (2,2´-azino-bis[3-ethylbenzthiazolin-6-sulfonic acid]) test, showed an increase with the highest dose of As in the interaction with SiO2 NPs. The application of As at low doses induced a greater accumulation of bioactive compounds in tomato fruit; however, these compounds decreased in high doses as well as via interaction with SiO2 NPs, indicating that there was an oxidative burst.

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Nutritional Importance of Carotenoids and Their Effect on Liver Health: A Review

Cited by 133 publications

References 149 publications

Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Chlorella sorokiniana Dietary Supplementation Increases Antioxidant Capacities and Reduces ROS Release in Mitochondria of Hyperthyroid Rat Liver

Impact of Silicon Nanoparticles on the Antioxidant Compounds of Tomato Fruits Stressed by Arsenic

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