Nutritional habits in functional dyspepsia and its subgroups: a comparative study

Göktaş, Zeynep; Köklü, Seyfettin; Dikmen, Derya; Öztürk, Ömer; Yılmaz, Bülent; Asıl, Mehmet; Korkmaz, Hüseyin Anıl; Tuna, Yaşar; Kekilli, Murat; Aksoy, Evrim Kahramanoğlu; Köklü, Hayretdin; Demir, Aslıhan; Köklü, Gülşah; Arslan, Serab

doi:10.3109/00365521.2016.1164238

Cited by 36 publications

(41 citation statements)

References 27 publications

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“…4,11 People with postprandial distress have unique duodenal pathology, namely increased duodenal identified, including fatty, fried or spicy foods, and carbonated drinks, and avoiding these may be of benefit. 23 …”

Section: Pathophysiologymentioning

confidence: 99%

Functional dyspepsia

Talley¹,

Goodsall²,

Potter³

2017

Aust Prescr

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Section: Pathophysiologymentioning

confidence: 99%

Functional dyspepsia

Talley¹,

Goodsall²,

Potter³

2017

Aust Prescr

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“…Another dietary intervention for the treatment of FD is medical food; defined by the United States Food and Drug Administration as foods which are formulated to be consumed or administered enterally under the supervision of a physician which is intended for the specific dietary management of a disease or condition. 40,41 Medical foods, unlike food supplements, require safety reviews by panels of toxicologists and must be generally recognized as safe for consumption, although phase 1, 2, and 3 trials are not required. 42 Hypnotherapy is more effective than medical treatment or supportive therapy plus placebo medication in both the short-and long-term management of FD.…”

Section: Dietary Management and Medical Foodmentioning

confidence: 99%

Non-pharmacological Approach in the Management of Functional Dyspepsia

Wang

Herndon²,

2020

J Neurogastroenterol Motil

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Functional dyspepsia (FD) is a common functional gastrointestinal disease which bears a significant burden on society and individuals. Despite the high prevalence of FD, its pathophysiology remains poorly understood and the treatment options are limited and unsatisfactory. In the absence of effective pharmacological treatments for FD, non-pharmacological approaches, including: reassurance, lifestyle modification, psychotherapy, dietary interventions, medical food, acupuncture, and electrical stimulation and modulation are sought after by many physicians and FD patients. In this article, we review clinical studies which investigate nonpharmacological therapies for FD. We will also discuss potential mechanisms involved in the therapeutic effects of these nonpharmacological approaches. Though the evidences to support the routine use of the non-pharmacological management is still lacking, the non-invasive nature and potentially minimal side-effects of these therapies may be attractive in the FD management. In order to confirm the clinical effectiveness of these non-pharmacological approaches, more well-conducted, methodologically rigorous, and large-scaled clinical trials are required. (J Neurogastroenterol Motil 2020;26:6-15)

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“…In a randomized controlled trial including 168 patients with FD and 135 healthy controls, high‐fat and fried and spicy foods were more likely to exacerbate symptoms in FD . Entry of meal components into the duodenum may be a key factor in the genesis of symptoms.…”

Section: Pathogenesismentioning

confidence: 99%

Functional dyspepsia and duodenal eosinophilia: A new model

Fan

Talley

2017

J of Digest Diseases

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Functional dyspepsia (FD) is a highly prevalent disorder that affects more than 10% of the population. In the past decade, the theoretical underpinning of the concept of FD has begun to change, in light of new data on the underlying pathophysiological mechanisms of this disorder, with a focus on the duodenum. The Rome IV criteria, published in 2016, note that gastroesophageal reflux disease and irritable bowel syndrome overlap with FD more than expected by chance, suggesting that they may be part of the same disease spectrum. Infection by Helicobacter pylori (H. pylori) may explain a minority of cases of FD and in the Rome IV criteria H. pylori-associated dyspepsia (defined as symptom relief after eradication therapy) is considered a separate entity. Duodenal inflammation characterized by increased eosinophils and in some cases mast cells, may impair the intestinal barrier. Post-infectious gastroenteritis is now an established risk factor for FD. Other risk factors may include atopy, owning herbivore pets and exposure to antibiotics, together with gastroduodenal microbiome disturbances. Small bowel homing T cells and increased cytokines in the circulation occur in FD, correlating with slow gastric emptying, and a possible association with autoimmune rheumatological disease supports background immune system activation. A genetic predisposition is possible. FD has been linked to psychological disorders, but in some cases psychological distress may be driven by gut mechanisms. Therapeutic options are limited and, aside from responders to H. pylori eradication, provide only modest and temporary relief. Advances in understanding FD may alter clinical practice, and the treatment of duodenal inflammation or microbiome alterations may lead to a cure for a subset of these patients in the future.

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Nutritional habits in functional dyspepsia and its subgroups: a comparative study

Abstract: Fatty and spicy foods and carbonated drinks were the most common symptom triggering food items in FD group. In subgroups, carbonated drinks and legumes were more likely to cause a symptom in PS-FD. Removing these food items during the course of treatment might help alleviate the symptoms.

Cited by 36 publications

References 27 publications

Functional dyspepsia

Functional dyspepsia

Non-pharmacological Approach in the Management of Functional Dyspepsia

Functional dyspepsia and duodenal eosinophilia: A new model

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