Nutritional disorders among elderly and senile patients depending on the state of renal function

Borkhanova, E.G. Borkhanova; Maksudova, A.N. Maksudova; Alaskari, S. Alaskari; Derbali, M. Derbali; Konyukhov, E.A. Konyukhov

doi:10.18565/nephrology.2022.2.19-24

Cited by 2 publications

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“…Полученные нами данные по распространенности вероятной ССА среди исследуемой популяции не противоречат данным литературы -17,4%. У этой категории лиц нами выявлен достоверно более высокий уровень коморбидности и риска неблагоприятных исходов, а также кровотечений, что согласуется с данными других исследователей [11]. Пациенты с неблагоприятным исходом достоверно чаще имели в анамнезе перенесенный ИМ (p=0,001) и СД (p=0,014), при поступлении на ЭКГ регистрировался чаще подъем ST (p=0,042) или блокады левой ножки пучка Гиса (p=0,001), ФП или трепетание предсердий (p=0,005).…”

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“…При наборе 0-2 баллов по шкале "Возраст не помеха" у пациента определяют отсутствие ССА, 3-4 баллов -диагностируется преастения, ≥5 баллов -ССА [4,5]. Распространенность ССА среди лиц старше 65 лет составляет ~10,7%, увеличиваясь до 52% среди лиц старше 85 лет [11].…”

Section: материал и методыunclassified

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Effect of senile asthenia syndrome on cardiovascular mortality within 12 months in patients over 70 years of age with myocardial infarction

2023

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Aim. This study aims to investigate the effect of senile asthenia syndrome (SAS) on the cardiovascular mortality risk within 12 months in patients over 70 years of age with myocardial infarction.Material and methods. We performed a retrospective study of 92 patients over 70 years of age with myocardial infarction, who agreed to participate. To detect senile asthenia syndrome, we used the questionnaire "Age is not a hindrance". We estimated the anamnestic data, and also laboratory and instrumental parameters. The follow-up period was 12 months. As an end-point, the onset of an adverse event — cardiovascular death was chosen. Statistical nonparametric methods, ROC analysis, Kaplan-Meier survival analysis (p<0,05) were used.Results. In 12 months, 19 patients (20,65%) met the end-point. The median (25%; 75%-quartile) of the numbers of points according to the questionnaire "Age is not a hindrance" was significantly higher in the group of dead patients than in the group without adverse outcomes — 4 (3; 5) and 2 (1; 4) points (p<0,001). When gaining 3 or more points according to the questionnaire "Age is not a hindrance", risk ratio of cardiovascular death within 12 months was 1,72; 95% confidence interval: 1,28-2,30 (p=0,001). In conduction of ROC analysis to predict adverse outcome when gaining 3 or more points according to the questionnaire "Age is not a hindrance", the area under the curve (AUC) was 0,78 (p<0,001), sensitivity — 89%, specificity — 60%.Conclusion. The risk of cardiovascular death within 12 months after myocardial infarction in patients over 70 years of age with SAS increases by 72%. The inclusion of the results from the questionnaire "Age is not a hindrance" into prognostic models, and the SAS estimation in this cohort of patients will improve the risk stratification.

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Effect of senile asthenia syndrome on cardiovascular mortality within 12 months in patients over 70 years of age with myocardial infarction

2023

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Nutritional disorders and survival rate of elderly and geriatric patients with CKD 3B-5 stage

Zaripova,

Almukhametova,

Maksudova

2024

Nefrologiâ (St.-Peterbg.)

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BACKGROUND. The prevalence of CKD in the population of the elderly and geriatric patients is varies from 23.4% to 35.8%. Nutritional status was recognized as an important factor of CKD prognosis. One of the factors affecting their survival is nutritional status. There have not been many studies on the effect of eating disorders on the survival of elderly and senile patients with CKD.THE AIM: to assess the impact of nutritional status on the survival of elderly patients with CKD stages 3b-5.PATIENTS AND METHODS. We’ve studied 190 people with CKD stages 3b-5 (eGFR<45 ml/min/m2) with an average age of 76 [67;86]. Exclusion criteria’s: dialysis, acute cardiovascular disorders, oncology, and psychiatric disorders. Nutritional status was assessed by Subjective Global Assessment scale, the 5-year risk of the death was evaluated absolute by the Bansal scale. The duration of study - 36 month.RESULTS. In the group of elderly and geriatric patients with CKD stages 3b-5, normal nutritional status was determined in 40.1% of patients, mild to moderate malnutrition in 54.7%, and protein-energy wasting (PEW) in 5.2%; up to 2.8% of patients were underweight. The best 3-year survival rate was observed in patients with normal nutritional status, mild nutritional status disorders and obesity, the worst survival rate - in patients with PEW and underweight (p<0,001). In the group of patients with CKD stage 4 the average Bansal score scale was 8 points, which corresponds to 69% of the absolute risk of death within 5 years; in patients with CKD stage 5, the average score was also 8 [7, 8]. CONCLUSION. In the group of elderly and geriatric patients with CKD stage 3b-5 and PEW survival rate was significantly lower than in patients without nutritional disorders and mild nutritional disorders; we didn’t find correlation between the estimated absolute risk of death according to the Bansal scale and actual survival in 3-year observation period.

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Nutritional disorders among elderly and senile patients depending on the state of renal function

Cited by 2 publications

References 0 publications

Effect of senile asthenia syndrome on cardiovascular mortality within 12 months in patients over 70 years of age with myocardial infarction

Effect of senile asthenia syndrome on cardiovascular mortality within 12 months in patients over 70 years of age with myocardial infarction

Nutritional disorders and survival rate of elderly and geriatric patients with CKD 3B-5 stage

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