Nutritional Aspects of Adult Liver Transplantation

Hasse, Jeanette M.

doi:10.1016/b978-0-7216-0118-2.50038-0

Cited by 18 publications

(24 citation statements)

References 81 publications

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“…Standard nutritional assessment instruments use laboratory tests, such as prothrombin time; albumin; prealbumin; transferrin; creatinine height index; and on tests of immune function, such as the delayed-type hypersensitivity reactions. 48-50 Because end-stage liver disease or cirrhosis confound the common measures of nutritional status, their utility in these patients is reduced. Patients with cirrhosis have significant impairment in their hepatic synthetic function that results in low serum albumin, prealbumin, transferrin levels, and prolonged prothrombin time.…”

Section: Methods To Assess Malnutrition In Cirrhosismentioning

confidence: 99%

Malnutrition in Cirrhosis: Contribution and Consequences of Sarcopenia on Metabolic and Clinical Responses

Periyalwar¹,

Dasarathy²

2012

Clinics in Liver Disease

211

232

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Section: Methods To Assess Malnutrition In Cirrhosismentioning

confidence: 99%

Malnutrition in Cirrhosis: Contribution and Consequences of Sarcopenia on Metabolic and Clinical Responses

Periyalwar¹,

Dasarathy²

2012

Clinics in Liver Disease

211

232

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“…PEM has been related to various adverse outcomes like decreased graft and patient survival after LT (8). Malnutrition was associated with prolonged ventilator support, longer intensive care unit and hospital stays (6,9).…”

Section: Introductionmentioning

confidence: 99%

“…Liver disease specifically affects such conventional markers of nutrition like serum proteins levels synthesized by the liver (albumin, transferrin, retinol-binding protein), and immunological dysfunction. Irrespective of these problems in nutrition assessment, diagnosis of malnutrition can be assessed in 20% of patients with compensated liver disease and in >80% with decompensated liver disease (4,8). Despite these findings there is no gold standard for the nutritional status assessment in LT.…”

Section: Introductionmentioning

confidence: 99%

Nutrition assessment and its effect on various clinical variables among patients undergoing liver transplant

Bakshi

Singh

2016

Hepatobiliary Surg. Nutr.

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Background: Malnutrition is highly prevalent in patients undergoing liver transplantation and has been associated to various clinical variables and outcome of the surgery. Methods:We recruited 54 adult patients undergoing living donor liver transplant (LT) as study sample. Results: Assessment of nutrition status represents a major challenge because of complications like fluid retention, hypoalbuminemia and hypoproteinemia. Different nutrition assessment tools show great disparity in the level of malnutrition among ESLD patients. In the present study recipient nutrition status evaluation by different nutrition assessment tools used showed malnutrition ranging from 3.7% to 100%. BMI and anthropometric measurements showed lower prevalence of malnutrition than phase angle and SGA whereas hand grip strength showed 100% malnutrition. Agreement among nutrition assessment methods showed moderate agreement (κ=0.444) of SGA with phase angle of the body. Malnutrition by different assessment tools was significantly associated to various clinical variables except MELD and days (ICU, Ventilator and Hospital). SGA was significantly (P<0.05) associated to majority of the clinical variables like aetiology, child Turcotte Pugh grades, degree of ascites, blood product usage , blood loss during the surgery, BIA (fat mass, FFM, muscle mass and body fat%). Conclusions:The different nutrition assessment tools showed great variability of results. SGA showed moderate agreement with phase angle of the body and was associated with various clinical and prognostic variables of liver transplantation.

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“…When compared with 24 control patients with a sham nasogastric tube, the only signifi cant benefi t seen was a decrease in viral infections (Hasse et al , 1995 ). Nevertheless, nutrition support guidelines have been published for the post -transplant patient (Hasse, 1990 ). For patients who have a longer ICU stay after transplantation, the experience of Reilly et al .…”

Section: Nutrition Support After Liver Transplantationmentioning

confidence: 99%