Nutrition management in acute pancreatitis: Clinical practice consideration

Lakananurak, Narisorn; Gramlich, Leah

doi:10.12998/wjcc.v8.i9.1561

Cited by 45 publications

(51 citation statements)

References 70 publications

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“…26 Hyperglycemia is often found in patients with pancreatitis and results from insulin resistance, increased glucose production in the liver, and impaired insulin secretion caused by beta-cell damage. 4 Hypocalcemia may be related to saponification of calcium, hypomagnesemia, decreased parathyroid hormone release, and an increased calcitonin concentration. 4 In our patient, the first signs of RFS were the onset of hypophosphatemia, hypocalcemia, and hyperglycemia.…”

Section: Discussionmentioning

confidence: 99%

“…4 Hypocalcemia may be related to saponification of calcium, hypomagnesemia, decreased parathyroid hormone release, and an increased calcitonin concentration. 4 In our patient, the first signs of RFS were the onset of hypophosphatemia, hypocalcemia, and hyperglycemia. However, her compromised condition was also delineated by a BMI of 17.8 kg/m 2 and the presence of hypertension.…”

Section: Discussionmentioning

confidence: 99%

“…4 Hypocalcemia may be related to saponification of calcium, hypomagnesemia, decreased parathyroid hormone release, and an increased calcitonin concentration. 4…”

Section: Discussionmentioning

confidence: 99%

“…3 No specific treatments are available for AP; management is focused on supportive interventions such as fluid resuscitation and nutritional intervention with the aim of reducing complications and modifying the course of the disease. 4 A potential risk associated with nutritional therapy in undernourished patients is the development of refeeding syndrome (RFS), a lethal clinical complication caused by metabolic disturbances and electrolyte shifts that occur during early nutritional rehabilitation. 5 Notably, RFS reflects the change from catabolic to anabolic metabolism and involves severe electrolyte imbalances (low serum concentrations of phosphate, magnesium, and potassium) as well as metabolic abnormalities in malnourished patients during refeeding by oral, enteral, or parenteral routes.…”

Section: Introductionmentioning

confidence: 99%

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Refeeding syndrome in a woman with pancreatitis: a case report

et al. 2021

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Refeeding syndrome can occur in malnourished patients with acute pancreatitis who have electrolyte imbalances. Refeeding syndrome is characterized by severe electrolyte imbalances (mainly hypophosphatemia, hypomagnesemia, and hypokalemia), vitamin deficiency (mainly thiamine deficiency), fluid overload, and salt retention resulting in organ dysfunction and cardiac arrhythmias. We herein report a case involving a patient with severe pancreatitis and gallbladder stones who developed refeeding syndrome with shock and loss of consciousness. The patient was treated by opportune vitamin and electrolyte supplementation therapy and showed substantial improvement after 2 weeks of hospitalization, gaining the ability to eat small bites of solid food orally. Early diagnosis and treatment of refeeding syndrome may reduce morbidity and mortality in patients with acute pancreatitis. Patients should be fasted only if alimentation is contraindicated, and electrolyte values must be closely monitored.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…4 Hypocalcemia may be related to saponification of calcium, hypomagnesemia, decreased parathyroid hormone release, and an increased calcitonin concentration. 4…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Refeeding syndrome in a woman with pancreatitis: a case report

et al. 2021

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“…The disease leads to undernutrition and disturbances of water/electrolyte and acid-base balance. Therefore, energy and protein requirements are higher in patients with SAP [ 17 , 18 , 19 ]. The pancreatic damage and infectious complications are associated with hyperglycemia which must be controlled, is induced by damage to beta cells, insulin resistance, and infectious complications.…”

Section: Introductionmentioning

confidence: 99%

Nutritional Support in Patients with Severe Acute Pancreatitis-Current Standards

Jabłońska

Mrowiec

2021

Nutrients

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Severe acute pancreatitis (SAP) leads to numerous inflammatory and nutritional disturbances. All SAP patients are at a high nutritional risk. It has been proven that proper nutrition significantly reduces mortality rate and the incidence of the infectious complications in SAP patients. According to the literature, early (started within 24–48 h) enteral nutrition (EN) is optimal in most patients. EN protects gut barrier function because it decreases gastrointestinal dysmotility secondary to pancreatic inflammation. Currently, the role of parenteral nutrition (PN) in SAP patients is limited to patients in whom EN is not possible or contraindicated. Early versus delayed EN, nasogastric versus nasojejunal tube for EN, EN versus PN in SAP patients and the role of immunonutrition (IN) in SAP patients are discussed in this review.

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Nutritional Support

Barrie,

Lobo

2024

Acute Pancreatitis

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Nutrition management in acute pancreatitis: Clinical practice consideration

Cited by 45 publications

References 70 publications

Refeeding syndrome in a woman with pancreatitis: a case report

Refeeding syndrome in a woman with pancreatitis: a case report

Nutritional Support in Patients with Severe Acute Pancreatitis-Current Standards

Nutritional Support

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