Nutrition Interventions Associated With Favorable Growth in Infants With Congenital Diaphragmatic Hernia

Abstract

Nutrition complications are common in survivors of congenital diaphragmatic hernia (CDH). Infants diagnosed with CDH may demonstrate poor growth despite receiving enteral tube feedings and gastroesophageal reflux treatment. This literature review was conducted to determine nutrition interventions resulting in favorable growth, which may improve outcomes in these infants. Results indicate that early nutrition support, including supplemental parenteral nutrition with provisions of ≥125 kcal/kg/d and ≥2.3 g/kg/d protein (which are higher than dietary reference intakes for infants), may have a positive impact on growth, potentially impacting neurological development.

First-year growth trajectory and early nutritional requirements for optimal growth in infants with congenital diaphragmatic hernia: a retrospective cohort study

“…Few studies have attempted to evaluate nutritional needs in infants with CDH. Based on calorimetric studies, Haliburton et al found that a mean caloric intake of 125±20 kcal/kg/day was required to achieve a weight gain of 25–35 g/kg/day 14 28. In the study by Terui et al , the caloric needs to achieve positive WGV at 2 months were estimated to be at least 122 kcal/kg/day in severe cases and 115 kcal/kg/day in others 23.…”

Poststationäre Ernährung bei Kindern mit angeborener Zwerchfellhernie

“…Nach Entlassung hatten 41% der befragten Familien sich wegen Ernährungsproblemen an Spezialisten gewandt; die Mehrheit ambulant (Kinderarzt, spezialisierte Nachsorge-Ambulanz, sonstiger Spezialist), und bei nur 7% war eine stationäre Behandlung wegen Ernährungsproblemen nötig. In insgesamt 64% konnten subjektiv Behandlungserfolge erzielt werden: durch hochkalorische Spezialnahrung (33%), medikamentöse Behandlung (32%), oder eine Magensonde (20%) 1 2 .…”