Nutrition in the Elderly

Refai, Wael; Seidner, Douglas L.

doi:10.1016/s0749-0690(18)30051-x

Cited by 14 publications

(6 citation statements)

References 80 publications

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“…These findings are in agreement with general nutritional recommendations for elderly people to have a balanced diet with a high proportion of fruits and vegetables -the 'prudent diet' [99]. At present, there is not enough evidence that promoting specific dietary habits may reduce the occurrence of dementia and AD.…”

Section: Resultssupporting

confidence: 81%

Nutritional Factors in Cerebral Aging and Dementia: Epidemiological Arguments for a Role of Oxidative Stress

Deschamps

Barberger‐Gateau

Peuchant³

et al. 2001

Neuroepidemiology

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There is increasing evidence that oxidative stress is involved in cerebral aging and dementia. The objective of this review is to give a progress report on the more recent results of the various epidemiologic cohorts studied for the association between nutrition of older people, the evolution of cognitive performances and the risk of later occurrence of dementia or stroke. The oxidative theory of pathological brain ageing is supported by animal laboratory experiments. Furthermore, experimental research has consistently suggested that diet-related factors play an important role in cognitive functions in ageing. In humans, a number of epidemiological case-control and prospective studies analyzed the association between nutrition, particularly fatty acids and antioxidant molecules (vitamins A, E, C, β-carotene and polyphenols) and cognition. In the context of evidence already available, further studies are needed to identify the specific role of various nutrients, their interactions and the influence of genetic factors and living habits on cerebral aging and dementia. Vascular dementia and Alzheimer’s disease, that share several risk factors, might be targets for primary prevention through nutritional recommendations and/or supplementation.

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Section: Resultssupporting

confidence: 81%

Nutritional Factors in Cerebral Aging and Dementia: Epidemiological Arguments for a Role of Oxidative Stress

Deschamps

Barberger‐Gateau

Peuchant³

et al. 2001

Neuroepidemiology

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“…Also, vitamin B12 deficiency is expected to be higher in elder Indians owing to high prevalence of Helicobacter pylori infection. The atrophic gastritis may also be implicated in the impaired B12 adsorption in the elderly population [31]. Thus, Hyperhomocysteinemia in Indians living in India is more attributable to low concentrations of vitamin B12 [32].…”

Section: Discussionmentioning

confidence: 99%

Levels of Plasma Homocysteine,Serum Vitamin B12 and Folic Acid in Primary Open Angle Glaucoma – A Case Control Study

2016

J Ocul Biol

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Purpose: To study the levels of Plasma homocysteine and serum vitamin B12 and folic acid in cases of Primary Open Angle Glaucoma (POAG).Method: It was a case-control cross sectional observational study for duration of one year. Calculated sample size was 28. The cases were randomly selected among all POAG patients >=40 yrs attending glaucoma clinic. Age and sex matched healthy individuals were recruited in the control group. Assay of homocysteine was carried out using the Human homocysteine, serum vitamin B12 and folic acid was carried out in both the groups statistical analysis was done using SPSS 20.0 version. The results were presented in mean ± SD and percentages. Unpaired t-test was used to compare the study parameters between cases and controls (CI= 95%; p<0.05significant). Pearson Correlation coefficient was used to find the correlation among the study parameters. Linear regression analysis was carried out to find the strength of the correlation between the study parameters.Results: Level of Vitamin B12 was significantly lower and homocysteine was significantly higher in the patients of advanced glaucoma than moderate and mild. There was poor negative correlation between vitamin B12 and homocysteine, vitamin B12 and Cup Disc Ratio (CDR). There was significant moderate correlation between CDR and homocysteine (r=0.47, p=0.01). Conclusion:Elevated homocysteine level may act as a pathological link on the progression of POAG. Understanding and characterizing its role in the pathogenesis POAG of could help in identifying novel target to combat this blinding disease which is the major cause of blindness in adults. Age in yearsNo.(n=28) %

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“…It is unclear if these normal physiological changes contribute to decreased food intake (Refai and Seidner 1999; Westenhoefer 2005). Other gastrointestinal changes occur with age and may affect oral intake.…”

Section: Issues In Nutrition Relevant To Frail Elderly Patientsmentioning

confidence: 99%

“…Oral and dental issues, esophageal motility, and atrophic gastritis may also affect nutritional status. The latter may be implicated in impaired vitamin B12 and iron adsorption (Refai and Seidner 1999). Dental problems (including poorly-fitting dentures) are often associated with nutrition problems (Morais et al 2003).…”

Section: Issues In Nutrition Relevant To Frail Elderly Patientsmentioning

confidence: 99%

Nutrition and aging: assessment and treatment of compromised nutritional status in frail elderly patients

Wells

Dumbrell²

2006

Clinical Interventions in Aging

114

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Nutrition is an important determinant of health in persons over the age of 65. Malnutrition in the elderly is often underdiagnosed. Careful nutritional assessment is necessary for both the successful diagnosis and development of comprehensive treatment plans for malnutrition in this population. The purpose of this article is to provide clinicians with an educational overview of this essential but often underecognized aspect of geriatric assessment. This article will review some common issues in nutrition for the elderly in both hospital and community settings. The complexity and impact of multiple comorbidities on the successful nutritional assessment of elderly patients is highlighted by using case scenarios to discuss nutritional issues common to elderly patients and nutritional assessment tools. Three case studies provide some context for an overview of these issues, which include the physiology of aging, weight loss, protein undernutrition, impaired cognition, malnutrition during hospitalization, screening procedures, and general dietary recommendations for patients 65 years of age and older.

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Nutrition in the Elderly

Cited by 14 publications

References 80 publications

Nutritional Factors in Cerebral Aging and Dementia: Epidemiological Arguments for a Role of Oxidative Stress

Nutritional Factors in Cerebral Aging and Dementia: Epidemiological Arguments for a Role of Oxidative Stress

Levels of Plasma Homocysteine,Serum Vitamin B12 and Folic Acid in Primary Open Angle Glaucoma – A Case Control Study

Nutrition and aging: assessment and treatment of compromised nutritional status in frail elderly patients

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