Nutrition could prevent or promote non-alcoholic fatty liver disease: an opportunity for intervention

Abstract

Manuel Romero-Gómez and colleagues discuss how diet and modifiable factors can help prevent of non-alcoholic fatty liver disease and the importance of engaging all society through awareness, education, and policy change

Challenges of obesity and type 2 diabetes require more attention to food environment

“…Population level drivers, and consequently opportunities for improved nutrition and prevention of disease outcomes, are also discussed by Romero-Gómez and colleagues in the context of non-alcoholic fatty liver disease. 12 They evaluate the evidence for the role of diet in the development of the disease and for prevention through promotion of dietary approaches such as the Mediterranean diet. Piernas and Merino also lay out the potential benefits of a healthy diet in lowering covid-19 risk and severity, especially for disadvantaged communities.…”

Mapping global research trends: Nutrition associations with nonalcoholic fatty liver disease - a Scopus bibliometric analysis

“…Consuming a diet abundant in saturated fatty acids (found in full-fat dairy products, ultra-processed foods, coconut and palm oils, and red meat) and sugars inundates the liver with fatty acids, exacerbating liver damage and promoting enlargement, dysfunction, systemic inflammation, and dysbiosis of adipose tissue. In contrast, achieving a 10% reduction in body weight through lifestyle changes, including the adoption of a low-fat hypocaloric diet in conjunction with regular exercise, facilitates the improvement of steatosis and inflammation and the reversal of fibrosis in patients with NAFLD[ 6 ].…”

Adherence to a Traditional Mexican Diet Is Associated with Lower Hepatic Steatosis in US-Born Hispanics of Mexican Descent with Overweight or Obesity

“…Dietary composition modulates the pathogenesis and trajectory of NAFLD [12,13]. A high intake of caloric-dense diets, particularly those rich in total fat and added sugars, has been implicated in the development and exacerbation of NAFLD [14].…”

“…A high intake of caloric-dense diets, particularly those rich in total fat and added sugars, has been implicated in the development and exacerbation of NAFLD [14]. Diets high in saturated and trans fats can contribute to lipid accumulation in the liver, leading to hepatic steatosis, a hallmark of NAFLD [13,15]. Furthermore, the excessive intake of sugars, especially fructose, has been associated with insulin resistance and lipogenesis in the liver [16,17].…”