Nutrition and psoriasis: is there any association between the severity of the disease and adherence to the Mediterranean diet?

Barrea, Luigi; Balato, Nicola; Somma, Carolina Di; Macchia, Paolo Emidio; Napolitano, Maddalena; Savanelli, Maria Cristina; Esposito, Katherine; Colao, Annamaria; Savastano, Silvia

doi:10.1186/s12967-014-0372-1

Cited by 122 publications

(114 citation statements)

References 46 publications

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“…Recent evidence has confirmed that adherence to a healthy diet over time reduces the risk of long-term inflammation [28]. The antioxidants present in the diet, such as omega-3 from fish oil, some vitamins (A, E, and C), and oligoelements (iron, copper, manganese, zinc, and selenium), which decrease oxidative stress and the production of reactive oxygen species, might be of particular relevance mainly in a chronic systemic inflammatory diseases, like psoriasis [29]. The Mediterranean diet is a healthy diet it is characterized by a high intake of fruit and vegetables, legumes, grains and cereals, fish and seafood, and nuts; a low intake of dairy products, meat and meat products; and a moderate ethanol intake mainly in the form of wine and during meals.…”

Section: Fish Oil and Psoriasismentioning

confidence: 93%

“…The Mediterranean diet is a healthy diet it is characterized by a high intake of fruit and vegetables, legumes, grains and cereals, fish and seafood, and nuts; a low intake of dairy products, meat and meat products; and a moderate ethanol intake mainly in the form of wine and during meals. Extra virgin olive oil (EVOO) is the main added lipid and its increased consumption is reflected in the high monounsaturated to saturated fatty acid intake [28,29]. However, there are few studies that relate to the Mediterranean diet with psoriasis.…”

Section: Fish Oil and Psoriasismentioning

confidence: 99%

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n-3 polyunsaturated fatty acids supplementation in psoriasis: a review

Mari

Simão

Dichi

2017

Nutrire

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Psoriasis is an immune mediated chronic inflammatory disease of unknown etiology and characterized by epidermal hyperplasia and inappropriate immune activation, which affects the skin and joints as well.The immunopathogenesis of psoriasis involves changes in the innate and acquired (T lymphocytes) immune system. The cells of the innate immune system when activated produce growth factors, cytokines, and chemokines that act on cells of the acquired immune system and vice versa, being characterized as atype 1 immune response disease. Fish oil n-3 polyunsaturated fatty acids, mainly eicosapentaenoic (EPA), and docosahexaenoic acids (DHA), reduce symptoms in many inflammatory skin diseases. The mechanism of action of fish oil in the treatment of psoriasis is widely based on the alteration of epidermal and blood cell membrane lipid composition. In the present study, we performed a review of the several studies, which analyzed the action of n-3 polyunsaturated fatty acids in patients with psoriasis. Taken together, the majority of the studies showed that n-3 polyunsaturated fatty acids, mainly from marine origin, have beneficial effects and can be utilized as adjuvant therapy in psoriasis treatment. Both oral and intravenous administration of fish oil n-3 polyunsaturated fatty acids had positive effects. However, further studies are warranted to answer many intriguing questions, for instance, the ideal quantity of fish oil to be utilized, the effect on different forms and severity of psoriasis and last, but not least, the consequences of using fish oil n-3 polyunsaturated fatty acids on the cardiovascular features of patients with psoriasis.

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Section: Fish Oil and Psoriasismentioning

confidence: 93%

Section: Fish Oil and Psoriasismentioning

confidence: 99%

n-3 polyunsaturated fatty acids supplementation in psoriasis: a review

Mari

Simão

Dichi

2017

Nutrire

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“…Several studies have evaluated the role of individual nutrients on psoriasis. Only a few of them have evaluated the benefits of healthy dietary patterns (Barrea et al, ) (Phan et al, ), and the effect of the Mediterranean diet on psoriasis with promising results.…”

Section: Introductionmentioning

confidence: 99%

Adherence to Mediterranean diet in Spanish patients with psoriasis: Cardiovascular benefits?

Molina-Leyva

Cuenca‐Barrales

Vega-Castillo

et al. 2019

Dermatologic Therapy

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Several studies have evaluated the role of individual nutrients on psoriasis. Only a few of them have evaluated the benefits of healthy dietary patterns and the effect of the Mediterranean diet on psoriasis with promising results. Moderate–severe psoriasis is associated with chronic systemic inflammation and increased cardiovascular risk. In this study the present authors measure the adherence to the Mediterranean diet to determine the grade of association with severity of psoriasis, a cardiovascular profile, and systemic inflammation. Our aim was to determine a cut‐off point that approximates the real clinical practice by differentiating patients with systemic or biological treatment.

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“…In patients with type 2 diabetes, diets based on low GI are associated with reductions in glycated hemoglobin (HbA1c) and fructosamine blood levels, two biomarkers used as key monitoring factors in diabetes management [52,53]. …”

Section: Dietary Patternsmentioning

confidence: 99%

Dietary Strategies Implicated in the Prevention and Treatment of Metabolic Syndrome

Iglesia

Loria-Kohen

Zulet

et al. 2016

IJMS

131

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Metabolic syndrome (MetS) is established as the combination of central obesity and different metabolic disturbances, such as insulin resistance, hypertension and dyslipidemia. This cluster of factors affects approximately 10%–50% of adults worldwide and the prevalence has been increasing in epidemic proportions over the last years. Thus, dietary strategies to treat this heterogenic disease are under continuous study. In this sense, diets based on negative-energy-balance, the Mediterranean dietary pattern, n-3 fatty acids, total antioxidant capacity and meal frequency have been suggested as effective approaches to treat MetS. Furthermore, the type and percentage of carbohydrates, the glycemic index or glycemic load, and dietary fiber content are some of the most relevant aspects related to insulin resistance and impaired glucose tolerance, which are important co-morbidities of MetS. Finally, new studies focused on the molecular action of specific nutritional bioactive compounds with positive effects on the MetS are currently an objective of scientific research worldwide. The present review summarizes some of the most relevant dietary approaches and bioactive compounds employed in the treatment of the MetS to date.

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Nutrition and psoriasis: is there any association between the severity of the disease and adherence to the Mediterranean diet?

Cited by 122 publications

References 46 publications

n-3 polyunsaturated fatty acids supplementation in psoriasis: a review

n-3 polyunsaturated fatty acids supplementation in psoriasis: a review

Adherence to Mediterranean diet in Spanish patients with psoriasis: Cardiovascular benefits?

Dietary Strategies Implicated in the Prevention and Treatment of Metabolic Syndrome

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