Nutrigenomics in Lifestyle Disorders: A Review

Manokaran, S.; Binoy, Ashly; Bhat, Dhrithi; Babu, Sarvesha; Bhat, Jahnavi G; H, Manjunatha Reddy A

doi:10.1149/10701.9249ecst

Cited by 2 publications

(3 citation statements)

References 79 publications

(98 reference statements)

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“…The findings show that most professional officers have time to eat in the evening (85.1%). They tend to get more than those who snack before work in the morning (58.1%) [36].…”

Section: Eating Pattern Of Police Personnelmentioning

confidence: 99%

“…A crosssectional study conducted to assess police health issues in Viayawada reported 58 % being average, 35 % being overweight and 7 % being obese. It has also been recorded that 25 % of police personnel were anaemic in agreement, majority (72%) of police personnel in Bangladesh had normal nutritional status, 24% were overweight, 3% were obese, while underweight was negligible [36,37].…”

Section: Nutritional Status Of Police Personnelmentioning

confidence: 99%

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An evaluation of Eating Pattern and Nutritional Status of Police Personnel in the Tamale Metropolis in Ghana

Bansah

2022

OJFN

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Police work is mentally demanding and stressful, which takes a heavy toll on the health of police personnel. This study was conducted to assess the eating pattern, physical activity and nutritional status of police personnel in the Tamale Metropolis. A cross-sectional research design was adopted for the study. The population of this study involved all the 1590 police personnel with two years working experience within the Tamale Metropolis in the Northern Region of Ghana. Simple random sampling technique was used to select three hundred and eighty-four ( 384) respondents for the study. The main instrument for data collection was questionnaire. Data were analyzed using Statistical Package for Social Sciences (SPSS) version 21.0. Chi-square and Fisher's exact tests were used to test associations. Logistic modeling was used to test the strength of the associations. P<0.05 was used to denote significance. The study revealed that the police eat two main meals, skip breakfast or eat in between meals, consume alcohol, ate foods belonging to the meat, soft drinks, fish, grain and eggs groups and their diet were more moderately diverse. The study also concluded the police personnel had normal BMI while was overweight and obese respectively. It is recommended that the police department should institute health education programs on the benefits of good dietary practices to achieve optimal health, to avoid the practice of police eating two main meals, skipping breakfast, consuming more alcohol but rather consumes diet that is moderately diverse to sustain him or her. It is also recommended that police department should institute a health education and screening exercise policy to examine the personals periodically to warrant their good health in the service.

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“…The findings show that most professional officers have time to eat in the evening (85.1%). They tend to get more than those who snack before work in the morning (58.1%) [36].…”

Section: Eating Pattern Of Police Personnelmentioning

confidence: 99%

Section: Nutritional Status Of Police Personnelmentioning

confidence: 99%

An evaluation of Eating Pattern and Nutritional Status of Police Personnel in the Tamale Metropolis in Ghana

Bansah

2022

OJFN

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“…Nevertheless, studies are scarcely comparable and reproducible not only because of the lack of standardized protocols, biological matrix or sample size but mainly because of the heterogeneous population and clinical variability included. Increasing evidence shows that disease-related intrinsic factors altogether with lifestyle factors may influence epigenetic mechanisms and identifying them is crucial to find unbiased reliable factors associated with a specific disease [27][28][29].…”

Section: Introductionmentioning

confidence: 99%

A study of differential microRNA expression profile in migraine: the microMIG exploratory study

et al. 2023

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Background Several studies have described potential microRNA (miRNA) biomarkers associated with migraine, but studies are scarcely reproducible primarily due to the heterogeneous variability of participants. Increasing evidence shows that disease-related intrinsic factors together with lifestyle (environmental factors), influence epigenetic mechanisms and in turn, diseases. Hence, the main objective of this exploratory study was to find differentially expressed miRNAs (DE miRNA) in peripheral blood mononuclear cells (PBMC) of patients with migraine compared to healthy controls in a well-controlled homogeneous cohort of non-menopausal women. Methods Patients diagnosed with migraine according to the International Classification of Headache Disorders (ICHD-3) and healthy controls without familial history of headache disorders were recruited. All participants completed a very thorough questionnaire and structured-interview in order to control for environmental factors. RNA was extracted from PBMC and a microarray system (GeneChip miRNA 4.1 Array chip, Affymetrix) was used to determine the miRNA profiles between study groups. Principal components analysis and hierarchical clustering analysis were performed to study samples distribution and random forest (RF) algorithms were computed for the classification task. To evaluate the stability of the results and the prediction error rate, a bootstrap (.632 + rule) was run through all the procedure. Finally, a functional enrichment analysis of selected targets was computed through protein–protein interaction networks. Results After RF classification, three DE miRNA distinguished study groups in a very homogeneous female cohort, controlled by factors such as demographics (age and BMI), life-habits (physical activity, caffeine and alcohol consumptions), comorbidities and clinical features associated to the disease: miR-342-3p, miR-532-3p and miR-758-5p. Sixty-eight target genes were predicted which were linked mainly to enriched ion channels and signaling pathways, neurotransmitter and hormone homeostasis, infectious diseases and circadian entrainment. Conclusions A 3-miRNA (miR-342-3p, miR-532-3p and miR-758-5p) novel signature has been found differentially expressed between controls and patients with migraine. Enrichment analysis showed that these pathways are closely associated with known migraine pathophysiology, which could lead to the first reliable epigenetic biomarker set. Further studies should be performed to validate these findings in a larger and more heterogeneous sample.

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Nutrigenomics in Lifestyle Disorders: A Review

Cited by 2 publications

References 79 publications

An evaluation of Eating Pattern and Nutritional Status of Police Personnel in the Tamale Metropolis in Ghana

An evaluation of Eating Pattern and Nutritional Status of Police Personnel in the Tamale Metropolis in Ghana

A study of differential microRNA expression profile in migraine: the microMIG exploratory study

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