Nutriential Hazards: Macronutrients: Essential Fatty Acids

Wilson, Belinda; Pollard, Ricquita D.; Ferguson, DavidL .

doi:10.1016/b978-0-12-378612-8.00250-x

Cited by 5 publications

(4 citation statements)

References 11 publications

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“…Vegetable oils, a major source of edible lipids, are an indispensable component of human diet, and appear to protect body tissues carrying liposoluble vitamins and containing a significant source of fatty acids, especially those essential fatty acids. Essential fatty acids (the omega-3 family α-linolenic acid and the omega-6 linoleic acid) constitute building blocks of longer chain fatty acids and have the role of mediants that regulate biological processes but are not synthesized endogenously and, therefore, have to be obtained in the diet [ 66 ]. Furthermore, to provide healthy food and, consequently, to create good quality food, especially including high quality vegetable oil, is one of society’s major challenges in terms of diet [ 67 ].…”

Section: Resultsmentioning

confidence: 99%

“…These metabolites can be classified into many groups and are commonly referred to as pro-resolving mediators (SPMs). Since fatty acids (FAs) can be stored as triglycerides, destroyed by oxidation, or utilized in the formation of phospholipids, the primary constituent of cellular membranes, they are frequently linked to structural and metabolic roles [ 66 ]. It has been demonstrated that these lipids act as regulators in several cell types.…”

Section: Resultsmentioning

confidence: 99%

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The In Vitro, Ex Vivo, and In Vivo Effect of Edible Oils: A Review on Cell Interactions

Tsamesidis

Kalogianni

2023

Pharmaceutics

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Consumption of edible oils is a significant part of the dietary pattern in the developed and developing world. Marine and vegetable oils are assumed to be part of a healthy food pattern, especially if one takes into account their potential role in protecting against inflammation, cardiovascular disease, and metabolic syndrome due to the presence of polyunsaturated fatty acids and minor bioactive compounds. Exploring the potential effect of edible fats and oils on health and chronic diseases is an emerging field worldwide. This study reviews the current knowledge of the in vitro, ex vivo, and in vivo effect of edible oils in contact with various cell types and aims to demonstrate which nutritional and bioactive components of a variety of edible oils present biocompatibility, antimicrobial properties, antitumor activity, anti-angiogenic activity, and antioxidant activity. Through this review, a wide variety of cell interactions with edible oils and their potential to counteract oxidative stress in pathological conditions are presented as well. Moreover, the gaps in current knowledge are also highlighted, and future perspectives on edible oils and their health benefits and potential to counteract a wide variety of diseases through possible molecular mechanisms are also discussed.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

The In Vitro, Ex Vivo, and In Vivo Effect of Edible Oils: A Review on Cell Interactions

Tsamesidis

Kalogianni

2023

Pharmaceutics

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“…Linoleic acid (LA, 18:2ω6) and α-linolenic acid (ALA, 18:3ω3) are considered the precursors of many PUFAs, such as docosahexaenoic acid (DHA, 22:6ω3) and eicosapentaenoic acid (EPA, 20:5ω3), which are produced from ALA (Figure 9). However, their bioconversion rate is low, ranging between 10 and14%, and thus insufficient to cover the nutritional needs of humans [157]. Subsequently, they should be provided directly through dietary sources.…”

Section: Polyunsaturated Fatty Acidsmentioning

confidence: 99%

Innovative Bioactive Products with Medicinal Value from Microalgae and Their Overall Process Optimization through the Implementation of Life Cycle Analysis—An Overview

Papadaki,

Tricha,

Panagiotopoulou

et al. 2024

Marine Drugs

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Microalgae are being recognized as valuable sources of bioactive chemicals with important medical properties, attracting interest from multiple industries, such as food, feed, cosmetics, and medicines. This review study explores the extensive research on identifying important bioactive chemicals from microalgae, and choosing the best strains for nutraceutical manufacturing. It explores the most recent developments in recovery and formulation strategies for creating stable, high-purity, and quality end products for various industrial uses. This paper stresses the significance of using Life Cycle Analysis (LCA) as a strategic tool with which to improve the entire process. By incorporating LCA into decision-making processes, researchers and industry stakeholders can assess the environmental impact, cost-effectiveness, and sustainability of raw materials of several approaches. This comprehensive strategy will allow for the choosing of the most effective techniques, which in turn will promote sustainable practices for developing microalgae-based products. This review offers a detailed analysis of the bioactive compounds, strain selection methods, advanced processing techniques, and the incorporation of LCA. It will serve as a valuable resource for researchers and industry experts interested in utilizing microalgae for producing bioactive products with medicinal properties.

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“…Edible vegetable oil contains ω‐6 linoleic acid (LA, C18:2) and ω‐3 α‐linolenic acid (ALA, C18:3), which are indispensable nutritional resources for human health (Ramsden et al., 2013; Swedberg, 2011). Indeed, ω‐6 LA and ω‐3 ALA are required for the function of multiple physiological systems, and both are essential in that they cannot be de novo synthesized by mammals; instead, they must be obtained from dietary sources (Galili et al., 2016; Wilson et al., 2014). A review of randomized controlled trials indicated that higher intake of ω‐6 polyunsaturated fatty acids (PUFAs), of which 80% to 90% contain ω‐6 LA, rather than SFAs, is inversely associated with the development of cardiovascular disease, coronary artery disease, and diabetes as well as death caused by cardiovascular disease (Maki et al., 2018).…”

Section: Introductionmentioning

confidence: 99%

Multi‐omics‐driven advances in the understanding of triacylglycerol biosynthesis in oil seeds

Li,

Che,

Zhu

et al. 2023

The Plant Journal

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SUMMARYVegetable oils are rich sources of polyunsaturated fatty acids and energy as well as valuable sources of human food, animal feed, and bioenergy. Triacylglycerols, which are comprised of three fatty acids attached to a glycerol backbone, are the main component of vegetable oils. Here, we review the development and application of multiple‐level omics in major oilseeds and emphasize the progress in the analysis of the biological roles of key genes underlying seed oil content and quality in major oilseeds. Finally, we discuss future research directions in functional genomics research based on current omics and oil metabolic engineering strategies that aim to enhance seed oil content and quality, and specific fatty acids components according to either human health needs or industrial requirements.

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Nutriential Hazards: Macronutrients: Essential Fatty Acids

Cited by 5 publications

References 11 publications

The In Vitro, Ex Vivo, and In Vivo Effect of Edible Oils: A Review on Cell Interactions

The In Vitro, Ex Vivo, and In Vivo Effect of Edible Oils: A Review on Cell Interactions

Innovative Bioactive Products with Medicinal Value from Microalgae and Their Overall Process Optimization through the Implementation of Life Cycle Analysis—An Overview

Multi‐omics‐driven advances in the understanding of triacylglycerol biosynthesis in oil seeds

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