Nutrient and food intake in relation to serum leptin concentration among young Japanese women

Murakami, Kentaro; Sasaki, Satoshi; Takahashi, Yoshiko; Uenishi, Kazuhiro; Yamasaki, Mitsuyo; Hayabuchi, Hitomi; Goda, Toshinao; Oka, Jun; Baba, Keiko; Ohki, Kohji; Watanabe, Reiko; Sugiyama, Yoshiko

doi:10.1016/j.nut.2007.04.006

Cited by 40 publications

(44 citation statements)

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“…The total polyphenol content of dried F. sycomorus leaves (12.33±0.26 mg gallic acid equivalent /g) [38] may also add another cause for such effect since polyphenols can prevent obesity via several mechanisms including suppression of fat absorption from the gut, uptake of glucose by skeletal muscles, suppression of anabolic pathways, stimulation of catabolic pathways in adipose, liver and other tissues, inhibition of angiogenesis in adipose tissues, inhibition of differentiation of pre-adipocytes to adipocytes and stimulation of apoptosis of mature adipocytes [39]. Because circulating leptin concentrations are commensurate with overall adipose mass [40] and there is a significant inverse association between dietary fibers and serum leptin concentration [41,42], FSLs -supplemented HFD diet, in the present study, had a lowering effect on serum leptin compared with HFD alone. This effect, in turn, resulted in a significant increase in daily feed intake.…”

Section: Discussionmentioning

confidence: 99%

Effect of Ficus sycomorus L. Leaves on High Fat Diet-Fed Rats: Possible Mechanisms behind the Prevention of Obesity and Its Related Disorders

El-Hashash¹

2014

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Section: Discussionmentioning

confidence: 99%

Effect of Ficus sycomorus L. Leaves on High Fat Diet-Fed Rats: Possible Mechanisms behind the Prevention of Obesity and Its Related Disorders

El-Hashash¹

2014

IOSRJESTFT

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“…It has been shown that consumption of dietary fibre is inversely associated with plasma leptin concentrations (Kuroda et al 2010;Murakami et al 2007), and results from clinical studies indicate that there is a positive correlation between plasma leptin and the concentration of TC (Kastarinen et al 2009). Several studies demonstrate that the rs7799039 polymorphism is associated with altered leptin levels (Ali et al 2009;Yiannakouris et al 2003).…”

Section: Discussionmentioning

confidence: 99%

Polymorphisms in LEP and NPY genes modify the response to soluble fibre Plantago ovata husk intake on cardiovascular risk biomarkers

et al. 2012

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The satiating effect of fibre consumption has been related to gut hormones, such as peptide YY and leptin. These peptides may also influence cardiovascular (CVD) risk biomarkers. Nevertheless, there is wide interindividual variation in metabolic responses to fibre consumption. The objective was to investigate differences in the effects of soluble fibre, in the form of Plantago ovata husk (Po-husk) treatment, on CVD risk biomarkers according to selected polymorphisms in genes related to satiety. The study was a multi-centred, double-blind, placebo-controlled, parallel and randomised trial in mildmoderate hypercholesterolaemic patients (age range: 43-67 years). Eight polymorphisms in three genes related to satiety (LEP, NPY and PYY) were identified in 178 participants; 88 patients in the placebo (microcrystalline cellulose 14 g/day) group and 90 in the Po-husk (14 g/day) group, which had added to a low-saturated-fat diet for 8 weeks. The CVD biomarkers measured included the following: lipid profile, blood pressure (BP), glucose, insulin, hs-CRP, oxidised LDL and IL-6. Relative to the placebo, Po-husk consumption lowered the plasma total cholesterol concentration by 3.3 % according to rs7799039 polymorphism in the LEP gene (p \ 0.05). Furthermore, the Po-husk reduced systolic BP (mean [95 % CI]) by -8 mmHg (-14.16; -1.90) and hs-CRP by 24.9 % in subjects with the AA genotype of the rs16147 polymorphism in the NPY gene (32 % of our total population; p \ 0.05), which remained significant after Bonferroni correction. In conclusion, polymorphisms in the LEP and NPY genes potentiate the response to Po-husk, particularly the effects on systolic BP and the hs-CRP plasma concentration.

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“…The high-fiber content of the 'Traditional' pattern ma y contribute to the inverse association with LEP. In two population samples of Japanese adults, a high total fiber intake was associated with low circulating LEP [51,52]. In one of these samples, an independent negative association was also found for legumes intake, such as beans, and serum LEP among women [52].…”

Section: Discussionmentioning

confidence: 84%

“…In two population samples of Japanese adults, a high total fiber intake was associated with low circulating LEP [51,52]. In one of these samples, an independent negative association was also found for legumes intake, such as beans, and serum LEP among women [52]. In Brazil, despite the reduction in household availability of beans observed in the last decades [53], these foods are important dietary sources of total fiber [54], and the most consumed vegetable protein-rich food, with their average usual consumption of about 87 grams (equivalent to 1 serving) in the population evaluated (data not shown).…”

Section: Discussionmentioning

confidence: 94%

“…The Goodness-of-fit of the model was assessed by different indexes namely the adjusted chi-squared test (²/degrees of freedom) 30 , the comparative fit index (CFI) 50 , the Tucker-Lewis index (TLI) 51 , the residual mean square error of approximation (RMSEA) 52 and its 90% confidence interval (90% CI), and the standardized root mean square residual (SRMR) 53,54 . , and SRMR (0.08) 53,54 .…”

Section: Foods Groupingmentioning

confidence: 99%

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Dieta e fatores de riscos metabólicos para doença cardiovascular em adultos e idosos residentes no município de São Paulo: uma análise por modelos de equações estruturais

Castro¹

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São Paulo 2015É expressamente proibida a comercialização deste documento, tanto na sua forma impressa como eletrônica. Sua reprodução total ou parcial é permitida exclusivamente para fins acadêmicos e científicos, desde que na reprodução figure a identificação do autor, título, instituição e ano da tese/dissertação. À Deus, pelas oportunidades e por seu infinito amor e bondade... À minha família, por todo apoio e amor incondicional! Agradecimentos À Profa. Assoc. Regina Mara Fisberg, minha querida e estimada orientadora, com sua competência, carisma e seu inquestionável bom-humor. Agradeço pela confiança e pelo apoio, carinho e respeito nesses quase nove anos de trabalho, amizade e convivência.Aos membros da banca examinadora, pela disponibilidade, leitura da tese e, sobretudo, pelas valiosas considerações. À Profa. Assoc. Dirce Maria Lobo Marchioni, pelo carinho, incentivo e pela sugestão do tema de pesquisa.À querida Valéria Troncoso Baltar, pela amizade, parceira, contribuições e pelas constantes tentativas de levar-me para a "cidade maravilhosa"! Ao Professor Marcelo Bulgarelli, meu querido mestre de língua portuguesa, jamais poderia deixar de agradecê-lo pelo aprendizado e incentivo! Ao Professor Michael Zellner, pelos ensinamentos de língua inglesa, pelas divertidas aulas e pelas revisões dos manuscritos. Thank you very much! À minha querida amiga Soraya Sant'Anna de Castro Selem, que mesmo distante, fez-se muito presente! À Bartira Mendes Gorgulho, pela grande e duradoura amizade, incentivo, companheirismo e pelos momentos de descontração nas viagens e passeios! À minha divertidíssima amiga Diva Aliete, por tonar o trabalho na 'salinha' muito mais alegre! À Jaqueline Lopes Pereira, exemplo fiel de doçura e serenidade que conquista e contagia a todos! (estudo ISA Capital -2008). Na primeira fase do estudo, 1.102 adultos e idosos, de ambos os sexos, foram entrevistados no domicílio, por meio da aplicação de questionário estruturado e do recordatório alimentar de 24 horas. Na segunda fase, 642 indivíduos adultos e idosos foram reavaliados quanto ao consumo alimentar por meio da aplicação, por telefone, do segundo recordatório alimentar, e, destes, 592 participaram da coleta domiciliar de amostras de sangue venoso, da medição antropométrica e da aferição da pressão arterial por técnico de enfermagem. Os alimentos relatados em ambos os recordatórios foram agrupados segundo a similaridade do valor nutricional e hábitos alimentares da população, e corrigidos pela variância intrapessoal da ingestão por procedimentos estatísticos da plataforma online Multiple Source Method. Os grupos de alimentos foram analisados por meio de análise fatorial exploratória e confirmatória (manuscrito 1) e por modelos de equações estruturais exploratórios (manuscrito 3), a fim de obter os padrões de dieta.O modelo conceitual da relação entre os fatores de risco metabólicos (leptina sérica, proteína C-reativa de alta sensibilidade sérica, pressão arterial sistólica e diastólica, razão colesterol total/lipoproteína de alta densidade, ...

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Nutrient and food intake in relation to serum leptin concentration among young Japanese women

Cited by 40 publications

References 18 publications

Effect of Ficus sycomorus L. Leaves on High Fat Diet-Fed Rats: Possible Mechanisms behind the Prevention of Obesity and Its Related Disorders

Effect of Ficus sycomorus L. Leaves on High Fat Diet-Fed Rats: Possible Mechanisms behind the Prevention of Obesity and Its Related Disorders

Polymorphisms in LEP and NPY genes modify the response to soluble fibre Plantago ovata husk intake on cardiovascular risk biomarkers

Dieta e fatores de riscos metabólicos para doença cardiovascular em adultos e idosos residentes no município de São Paulo: uma análise por modelos de equações estruturais

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